FI821164L - Nya 2,3,4-trinor-m-inter-fenylen-prostaglandinderivat och foerfarande foer deras framstaellning - Google Patents

Nya 2,3,4-trinor-m-inter-fenylen-prostaglandinderivat och foerfarande foer deras framstaellning

Info

Publication number
FI821164L
FI821164L FI821164A FI821164A FI821164L FI 821164 L FI821164 L FI 821164L FI 821164 A FI821164 A FI 821164A FI 821164 A FI821164 A FI 821164A FI 821164 L FI821164 L FI 821164L
Authority
FI
Finland
Prior art keywords
prostaglandinderivat
trinor
nya
phenylene
inter
Prior art date
Application number
FI821164A
Other languages
English (en)
Other versions
FI821164A0 (fi
FI75156C (fi
FI75156B (fi
Inventor
Istvan Szekely
Krisztina Kekesi
Mariann Lovasz
Sandor Botar
Pal Hadhazy
Istvan Rakoczi
Laszlo Muszbek
Judit Skopal
Istvan Stadler
Karoly Horvath
Gabor Kovacs
Peter Koermoeczy
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HU96281A external-priority patent/HU189974B/hu
Priority claimed from HU96381A external-priority patent/HU188286B/hu
Priority claimed from HU96481A external-priority patent/HU188009B/hu
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of FI821164A0 publication Critical patent/FI821164A0/fi
Publication of FI821164L publication Critical patent/FI821164L/fi
Application granted granted Critical
Publication of FI75156B publication Critical patent/FI75156B/fi
Publication of FI75156C publication Critical patent/FI75156C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI821164A 1981-04-14 1982-04-02 Foerfarande foer framstaellning av nya 2,3,4-trinor-m-inter-fenylen-prosta-cyklinderivat med blodplatteaggregationshaemmande effekt. FI75156C (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
HU96281A HU189974B (hu) 1981-04-14 1981-04-14 Eljárás 2,3,4-trinor-m-iníer-fenilidén-PGI2 származékok előállítására
HU96381A HU188286B (hu) 1981-04-14 1981-04-14 ELJÁRÁS 23,4-TRINOR-M-INTER-FENILIDÉN-PGl! SZÁRMAZÉKOK ELŐÁLLÍTÁSÁRA
HU96481 1981-04-14
HU96481A HU188009B (en) 1981-04-14 1981-04-14 Process for preparing new derivatives of 2,3,4-trinor-1,5-inter-m-phenylene-pgt down 2alpha
HU96281 1981-04-14
HU96381 1981-04-14

Publications (4)

Publication Number Publication Date
FI821164A0 FI821164A0 (fi) 1982-04-02
FI821164L true FI821164L (fi) 1982-10-15
FI75156B FI75156B (fi) 1988-01-29
FI75156C FI75156C (fi) 1988-05-09

Family

ID=27269950

Family Applications (1)

Application Number Title Priority Date Filing Date
FI821164A FI75156C (fi) 1981-04-14 1982-04-02 Foerfarande foer framstaellning av nya 2,3,4-trinor-m-inter-fenylen-prosta-cyklinderivat med blodplatteaggregationshaemmande effekt.

Country Status (12)

Country Link
US (1) US4451483A (fi)
EP (1) EP0062902B1 (fi)
AT (1) AT381494B (fi)
CS (1) CS241102B2 (fi)
DD (1) DD202434A5 (fi)
DE (1) DE3268487D1 (fi)
DK (1) DK165882A (fi)
FI (1) FI75156C (fi)
GR (1) GR76127B (fi)
IL (1) IL65387A0 (fi)
PL (1) PL129427B1 (fi)
SU (1) SU1138020A3 (fi)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU188559B (en) * 1981-12-01 1986-04-28 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu Process for preparing new inter-m-phenylene-prostacyclin derivatives
IL67332A (en) * 1981-12-01 1985-12-31 Chinoin Gyogyszer Es Vegyeszet Inter-m-phenylene-prostacyclin analogues,process for the preparation thereof and pharmaceutical compositions containing them
HU190007B (en) * 1982-05-06 1986-08-28 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu Process for producing new aromatic prostacylin analogues
DE3317159A1 (de) * 1982-05-27 1983-12-01 Grünenthal GmbH, 5190 Stolberg Verfahren zur herstellung von 5z-formen von 2,3,4-trinor-1,5-inter-m-phenylen- prostacyclinderivaten
US4474804A (en) * 1983-09-19 1984-10-02 E. R. Squibb & Sons, Inc. 7-Oxabicyclo substituted prostaglandin phenyl carboxylic acid derivatives useful as cardiovascular agents
DE3408699A1 (de) * 1984-03-08 1985-09-12 Schering AG, 1000 Berlin und 4709 Bergkamen Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
US5661178A (en) * 1995-09-01 1997-08-26 Allergan Method for effecting vasodilation with (1,5-inter)aryl prostaglandin derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE795200A (fr) * 1972-05-10 1973-08-09 Ciba Geigy Nouveaux oxabicyclooctanes et leurs procedes de preparation
HU179001B (en) * 1978-05-29 1982-08-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 5-halo-6,9alpha-oxido-prostaglandin derivatives
US4312810A (en) * 1978-11-22 1982-01-26 The Upjohn Company 2,5-Inter-o-phenylene-3,4-dinor-5,9α-epoxy-9-deoxy-PGF1 compounds
DE3029984C2 (de) * 1980-08-08 1983-12-15 Grünenthal GmbH, 5190 Stolberg 2-Oxabicyclo [3.3.0] octanderivate und diese enthaltende Arzneimittel

Also Published As

Publication number Publication date
FI821164A0 (fi) 1982-04-02
DD202434A5 (de) 1983-09-14
PL235949A1 (en) 1983-01-03
GR76127B (fi) 1984-08-03
EP0062902A1 (de) 1982-10-20
CS256182A2 (en) 1985-07-16
CS241102B2 (en) 1986-03-13
FI75156C (fi) 1988-05-09
DE3268487D1 (en) 1986-02-27
IL65387A0 (en) 1982-05-31
US4451483A (en) 1984-05-29
PL129427B1 (en) 1984-05-31
DK165882A (da) 1982-10-15
SU1138020A3 (ru) 1985-01-30
EP0062902B1 (de) 1986-01-15
FI75156B (fi) 1988-01-29
AT381494B (de) 1986-10-27
ATA139282A (de) 1986-03-15

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Legal Events

Date Code Title Description
MM Patent lapsed
MM Patent lapsed

Owner name: CHINOIN GYOGUSZER ES VEGYESZETI TERMEKEK