FI812808L - Fenylpiperazinderivat med antiagressiv aktivitet - Google Patents
Fenylpiperazinderivat med antiagressiv aktivitetInfo
- Publication number
- FI812808L FI812808L FI812808A FI812808A FI812808L FI 812808 L FI812808 L FI 812808L FI 812808 A FI812808 A FI 812808A FI 812808 A FI812808 A FI 812808A FI 812808 L FI812808 L FI 812808L
- Authority
- FI
- Finland
- Prior art keywords
- phenylpiperazinderivat
- antiagressiv
- aktivitet
- med
- phenylpiperazinderivat med
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/56—Amides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Anesthesiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL8005133A NL8005133A (nl) | 1980-09-12 | 1980-09-12 | Fenylpiperazinederivaten met antiagressieve werking. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FI812808L true FI812808L (fi) | 1982-03-13 |
Family
ID=19835870
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI812808A FI812808L (fi) | 1980-09-12 | 1981-09-09 | Fenylpiperazinderivat med antiagressiv aktivitet |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0048045A1 (fr) |
| JP (1) | JPS5781464A (fr) |
| AU (1) | AU7502981A (fr) |
| CA (1) | CA1155116A (fr) |
| CS (1) | CS228532B2 (fr) |
| DD (1) | DD202152A5 (fr) |
| DK (1) | DK400081A (fr) |
| ES (1) | ES505373A0 (fr) |
| FI (1) | FI812808L (fr) |
| GR (1) | GR75079B (fr) |
| HU (1) | HU184966B (fr) |
| IL (1) | IL63784A0 (fr) |
| NL (1) | NL8005133A (fr) |
| PL (1) | PL232965A1 (fr) |
| YU (1) | YU217381A (fr) |
| ZA (1) | ZA816256B (fr) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA848005B (en) * | 1983-10-17 | 1985-05-29 | Duphar Int Res | Blood-pressure lowering piperazine derivatives |
| EP0185429A1 (fr) * | 1984-12-21 | 1986-06-25 | Duphar International Research B.V | Pipérazines bicycliques |
| US4778796A (en) * | 1985-07-19 | 1988-10-18 | Dainippon Pharmaceutical Co., Ltd. | ω-(3-pyridyl)alkenamide derivatives and anti-allergenic pharmaceutical compositions containing same |
| US5254552A (en) * | 1988-05-24 | 1993-10-19 | American Home Products Corporation | Aryl-and heteroaryl piperazinyl carboxamides having central nervous system activity |
| US5010078A (en) * | 1988-05-24 | 1991-04-23 | American Home Products Corporation | Aryl- and heteroaryl piperazinyl carboxamides having central nervous system activity |
| GB8909209D0 (en) * | 1989-04-22 | 1989-06-07 | Wyeth John & Brother Ltd | Piperazine derivatives |
| US5192779A (en) * | 1989-02-14 | 1993-03-09 | Fujisawa Pharmaceutical Co., Ltd. | Substituted-acetamide compound and a process for the preparation thereof |
| US5066680A (en) * | 1989-02-14 | 1991-11-19 | Fujisawa Pharmaceutical Co., Ltd. | Novel substituted-acetamide compound and a process for the preparation thereof |
| IE950248L (en) * | 1989-04-22 | 1990-10-22 | Wyeth John & Brother Ltd | Piperazine derivatives |
| US5340812A (en) * | 1989-04-22 | 1994-08-23 | John Wyeth & Brother, Limited | Piperazine derivatives |
| US5382583A (en) * | 1989-04-22 | 1995-01-17 | John Wyeth & Brother, Limited | Piperazine derivatives |
| GB2230780B (en) * | 1989-04-22 | 1992-10-21 | American Home Prod | Tertiary alkyl functionalized piperazine derivatives |
| US5939412A (en) * | 1992-06-26 | 1999-08-17 | Smithkline Beecham Corporation | Bicyclic fibrinogen antagonists |
| WO1993000095A2 (fr) * | 1991-06-28 | 1993-01-07 | Smithkline Beecham Corporation | Antagonistes bicycliques de fibrinogene |
| GB9200293D0 (en) * | 1992-01-08 | 1992-02-26 | Wyeth John & Brother Ltd | Piperazine derivatives |
| SE9201138D0 (sv) * | 1992-04-09 | 1992-04-09 | Astra Ab | Novel phthalimidoalkylpiperazines |
| JPH0771521B2 (ja) * | 1992-07-08 | 1995-08-02 | 功司 後藤 | 靴の製法 |
| AU689762B2 (en) * | 1992-12-21 | 1998-04-09 | Smithkline Beecham Corporation | Bicyclic fibrinogen antagonists |
| IT1266582B1 (it) * | 1993-07-30 | 1997-01-09 | Recordati Chem Pharm | Derivati (di)azacicloesanici e diazacicloeptanici |
| US6403578B1 (en) | 1993-12-21 | 2002-06-11 | Smithkline Beecham Corporation | Bicyclic fibrinogen antagonists |
| MA23420A1 (fr) * | 1994-01-07 | 1995-10-01 | Smithkline Beecham Corp | Antagonistes bicycliques de fibrinogene. |
| US6458784B1 (en) | 1994-06-29 | 2002-10-01 | Smithkline Beecham Corporation | Vitronectin receptor antagonists |
| US5661163A (en) * | 1995-06-07 | 1997-08-26 | Merck & Co., Inc. | Alpha-1a adrenergic receptor antagonists |
| US5977101A (en) * | 1995-06-29 | 1999-11-02 | Smithkline Beecham Corporation | Benzimidazoles/Imidazoles Linked to a Fibrinogen Receptor Antagonist Template Having Vitronectin Receptor Antagonist Activity |
| US5807856A (en) * | 1995-11-15 | 1998-09-15 | Merck & Co., Inc. | Alpha 1a adrenergic receptor antagonist |
| ATE229946T1 (de) * | 1996-04-05 | 2003-01-15 | Sod Conseils Rech Applic | Alpha-1 adrenergischer rezeptor antagonisten |
| US6451816B1 (en) | 1997-06-20 | 2002-09-17 | Klinge Pharma Gmbh | Use of pyridyl alkane, pyridyl alkene and/or pyridyl alkine acid amides in the treatment of tumors or for immunosuppression |
| DE19624704A1 (de) * | 1996-06-20 | 1998-01-08 | Klinge Co Chem Pharm Fab | Neue Pyridylalkansäureamide |
| DE19624659A1 (de) | 1996-06-20 | 1998-01-08 | Klinge Co Chem Pharm Fab | Neue Pyridylalken- und Pyridylalkinsäureamide |
| DE19756212A1 (de) | 1997-12-17 | 1999-07-01 | Klinge Co Chem Pharm Fab | Neue, mit einem cyclischen Imid substituierte Pyridylalkan-, alken- und -alkincarbonsäureamide |
| US6903118B1 (en) | 1997-12-17 | 2005-06-07 | Klinge Pharma Gmbh | Piperazinyl-substituted pyridylalkane, alkene and alkine carboxamides |
| DE19756235A1 (de) | 1997-12-17 | 1999-07-01 | Klinge Co Chem Pharm Fab | Neue piperidinylsubstituierte Pyridylalkan- alken- und -alkincarbonsäureamide |
| DE19756236A1 (de) * | 1997-12-17 | 1999-07-01 | Klinge Co Chem Pharm Fab | Neue piperazinylsubstituierte Pyridylalkan-, alken- und -alkincarbonsäureamide |
| DE19756261A1 (de) | 1997-12-17 | 1999-07-01 | Klinge Co Chem Pharm Fab | Neue arylsubstituierte Pyridylalkan-, alken- und alkincarbonsäureamide |
| EP1031564A1 (fr) | 1999-02-26 | 2000-08-30 | Klinge Pharma GmbH | Inhibiteurs de la formation du nicotinamide mononucléotide et leur utilisation dans le traitement du cancer |
| AU2003235442A1 (en) | 2002-04-12 | 2003-10-27 | Sepracor, Inc. | 3-aza- and 1,4-diaza-bicyclo(4.3.0)nonanes, and methods of use thereof |
| JP2005538974A (ja) * | 2002-07-04 | 2005-12-22 | シュバルツ ファルマ アクチェンゲゼルシャフト | 中枢神経系の病気を治療するドーパミン−ｄ３リガンドとして使用するためのヘテロアレーンカルボキサミド |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1088058B (de) * | 1956-08-21 | 1960-09-01 | Davis & Company | Verfahren zur Herstellung von sympatholytisch wirkenden N-o-Halogenphenyl-N'-acylamino-alkylpiperazinen und deren Saeuresalzen |
| GB1166364A (en) * | 1966-11-25 | 1969-10-08 | American Cyanamid Co | N-(Tert-Aminoalkyl) Amide Derivatives and Process for Preparing the Same |
| BE788280A (fr) * | 1971-09-04 | 1973-02-28 | Pfizer | Nouvelles 1-(3-trifluoro-methyl-phenyl)-4-((amido cyclique)- alkyl) piperazines et composition pharmaceutique les contenant |
| AU532411B2 (en) * | 1979-03-01 | 1983-09-29 | Duphar International Research B.V. | Phenyl piperazine derivatives |
-
1980
- 1980-09-12 NL NL8005133A patent/NL8005133A/nl not_active Application Discontinuation
-
1981
- 1981-08-25 EP EP81200929A patent/EP0048045A1/fr not_active Withdrawn
- 1981-09-08 GR GR66001A patent/GR75079B/el unknown
- 1981-09-08 AU AU75029/81A patent/AU7502981A/en not_active Abandoned
- 1981-09-08 HU HU812582A patent/HU184966B/hu unknown
- 1981-09-09 FI FI812808A patent/FI812808L/fi not_active Application Discontinuation
- 1981-09-09 DD DD81233166A patent/DD202152A5/de unknown
- 1981-09-09 PL PL23296581A patent/PL232965A1/xx unknown
- 1981-09-09 ZA ZA816256A patent/ZA816256B/xx unknown
- 1981-09-09 IL IL63784A patent/IL63784A0/xx unknown
- 1981-09-09 YU YU02173/81A patent/YU217381A/xx unknown
- 1981-09-09 DK DK400081A patent/DK400081A/da not_active Application Discontinuation
- 1981-09-09 CS CS816656A patent/CS228532B2/cs unknown
- 1981-09-09 JP JP56141150A patent/JPS5781464A/ja active Pending
- 1981-09-10 ES ES505373A patent/ES505373A0/es active Granted
- 1981-09-11 CA CA000385649A patent/CA1155116A/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AU7502981A (en) | 1982-03-18 |
| YU217381A (en) | 1983-09-30 |
| NL8005133A (nl) | 1982-04-01 |
| JPS5781464A (en) | 1982-05-21 |
| ZA816256B (en) | 1982-08-25 |
| EP0048045A1 (fr) | 1982-03-24 |
| DD202152A5 (de) | 1983-08-31 |
| ES8302681A1 (es) | 1982-12-01 |
| DK400081A (da) | 1982-03-13 |
| IL63784A0 (en) | 1981-12-31 |
| GR75079B (fr) | 1984-07-13 |
| HU184966B (en) | 1984-11-28 |
| CS228532B2 (en) | 1984-05-14 |
| ES505373A0 (es) | 1982-12-01 |
| PL232965A1 (fr) | 1982-10-25 |
| CA1155116A (fr) | 1983-10-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD | Application lapsed |
Owner name: DUPHAR INTERNATIONAL RESEARCH B.V |