FI80273C - Foerfarande foer framstaellning av nya terapeutiskt anvaendbara /3h/-imidazo/5,1-d/-1,2,3,5,-tetrazin-4-on- derivat. - Google Patents
Foerfarande foer framstaellning av nya terapeutiskt anvaendbara /3h/-imidazo/5,1-d/-1,2,3,5,-tetrazin-4-on- derivat. Download PDFInfo
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- FI80273C FI80273C FI832927A FI832927A FI80273C FI 80273 C FI80273 C FI 80273C FI 832927 A FI832927 A FI 832927A FI 832927 A FI832927 A FI 832927A FI 80273 C FI80273 C FI 80273C
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- 238000000034 method Methods 0.000 title claims description 24
- 230000001225 therapeutic effect Effects 0.000 title description 4
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- 238000002360 preparation method Methods 0.000 claims description 46
- 125000000217 alkyl group Chemical group 0.000 claims description 23
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 17
- -1 alkali metal salt Chemical class 0.000 claims description 16
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims description 14
- 125000004432 carbon atom Chemical group C* 0.000 claims description 13
- 229910052757 nitrogen Inorganic materials 0.000 claims description 9
- 125000004397 aminosulfonyl group Chemical group NS(=O)(=O)* 0.000 claims description 8
- 150000004905 tetrazines Chemical class 0.000 claims description 8
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- 125000003884 phenylalkyl group Chemical group 0.000 claims description 5
- 125000005843 halogen group Chemical group 0.000 claims description 4
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- 238000009472 formulation Methods 0.000 claims description 2
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/88—Nitrogen atoms, e.g. allantoin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/91—Nitro radicals
- C07D233/92—Nitro radicals attached in position 4 or 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8223583 | 1982-08-17 | ||
| GB8223580 | 1982-08-17 | ||
| GB8223580 | 1982-08-17 | ||
| GB8223583 | 1982-08-17 | ||
| GB8226169 | 1982-09-14 | ||
| GB8226169 | 1982-09-14 | ||
| GB838306904A GB8306904D0 (en) | 1983-03-14 | 1983-03-14 | Compositions of matter |
| GB8306904 | 1983-03-14 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| FI832927A0 FI832927A0 (fi) | 1983-08-15 |
| FI832927A FI832927A (fi) | 1984-02-18 |
| FI80273B FI80273B (fi) | 1990-01-31 |
| FI80273C true FI80273C (fi) | 1990-05-10 |
Family
ID=27449377
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI832927A FI80273C (fi) | 1982-08-17 | 1983-08-15 | Foerfarande foer framstaellning av nya terapeutiskt anvaendbara /3h/-imidazo/5,1-d/-1,2,3,5,-tetrazin-4-on- derivat. |
Country Status (18)
| Country | Link |
|---|---|
| AU (1) | AU575782B2 (fr) |
| BE (1) | BE897548A (fr) |
| CA (1) | CA1254563A (fr) |
| CH (1) | CH657855A5 (fr) |
| DE (1) | DE3329505A1 (fr) |
| DK (1) | DK374983A (fr) |
| ES (1) | ES524995A0 (fr) |
| FI (1) | FI80273C (fr) |
| FR (1) | FR2531958B1 (fr) |
| GR (1) | GR78688B (fr) |
| HU (1) | HU189321B (fr) |
| IE (1) | IE55849B1 (fr) |
| IL (1) | IL69500A (fr) |
| IT (1) | IT1194375B (fr) |
| LU (1) | LU84969A1 (fr) |
| NL (1) | NL8302863A (fr) |
| NZ (1) | NZ205272A (fr) |
| SE (1) | SE455198B (fr) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2932305A1 (de) * | 1979-08-09 | 1981-02-26 | Basf Ag | Azolo- eckige klammer auf 5,1-d eckige klammer zu - eckige klammer auf 1,2,3,5 eckige klammer zu -tetrazin-4-one und verfahren zur herstellung dieser verbindungen |
| OA07174A (fr) * | 1981-08-24 | 1984-04-30 | May & Baker Ltd | Nouvelles imidazotétrazionones, leur préparation et les médicaments qui les contiennent. |
-
1983
- 1983-08-12 FR FR8313246A patent/FR2531958B1/fr not_active Expired
- 1983-08-12 GR GR72210A patent/GR78688B/el unknown
- 1983-08-15 CA CA000434582A patent/CA1254563A/fr not_active Expired
- 1983-08-15 HU HU832860A patent/HU189321B/hu unknown
- 1983-08-15 SE SE8304415A patent/SE455198B/sv not_active IP Right Cessation
- 1983-08-15 IE IE1913/83A patent/IE55849B1/xx unknown
- 1983-08-15 AU AU17968/83A patent/AU575782B2/en not_active Ceased
- 1983-08-15 IL IL69500A patent/IL69500A/xx unknown
- 1983-08-15 FI FI832927A patent/FI80273C/fi not_active IP Right Cessation
- 1983-08-15 NZ NZ205272A patent/NZ205272A/en unknown
- 1983-08-15 NL NL8302863A patent/NL8302863A/nl not_active Application Discontinuation
- 1983-08-16 DK DK374983A patent/DK374983A/da not_active Application Discontinuation
- 1983-08-16 LU LU84969A patent/LU84969A1/fr unknown
- 1983-08-16 IT IT22566/83A patent/IT1194375B/it active
- 1983-08-16 DE DE3329505A patent/DE3329505A1/de not_active Withdrawn
- 1983-08-17 BE BE0/211366A patent/BE897548A/fr not_active IP Right Cessation
- 1983-08-17 CH CH4490/83A patent/CH657855A5/fr not_active IP Right Cessation
- 1983-08-17 ES ES83524995A patent/ES524995A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| CA1254563A (fr) | 1989-05-23 |
| IE831913L (en) | 1984-02-17 |
| IL69500A (en) | 1989-01-31 |
| SE8304415D0 (sv) | 1983-08-15 |
| FR2531958B1 (fr) | 1986-10-31 |
| FI832927A (fi) | 1984-02-18 |
| IT8322566A0 (it) | 1983-08-16 |
| AU575782B2 (en) | 1988-08-11 |
| ES8502441A1 (es) | 1985-01-01 |
| GR78688B (fr) | 1984-09-27 |
| FI80273B (fi) | 1990-01-31 |
| CH657855A5 (fr) | 1986-09-30 |
| NL8302863A (nl) | 1984-03-16 |
| HU189321B (en) | 1986-06-30 |
| FI832927A0 (fi) | 1983-08-15 |
| BE897548A (fr) | 1984-02-17 |
| SE455198B (sv) | 1988-06-27 |
| DE3329505A1 (de) | 1984-02-23 |
| NZ205272A (en) | 1986-12-05 |
| IT1194375B (it) | 1988-09-22 |
| DK374983A (da) | 1984-02-18 |
| ES524995A0 (es) | 1985-01-01 |
| IE55849B1 (en) | 1991-01-30 |
| DK374983D0 (da) | 1983-08-16 |
| SE8304415L (sv) | 1984-02-18 |
| LU84969A1 (fr) | 1984-03-23 |
| AU1796883A (en) | 1984-02-23 |
| FR2531958A1 (fr) | 1984-02-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM | Patent lapsed |
Owner name: MAY & BAKER LIMITED |