DE69907042T2 - Ein Verfahren zur Herstellung von Naphthyridonen und Zwischenprodukten - Google Patents

Ein Verfahren zur Herstellung von Naphthyridonen und Zwischenprodukten

Info

Publication number
DE69907042T2
DE69907042T2 DE69907042T DE69907042T DE69907042T2 DE 69907042 T2 DE69907042 T2 DE 69907042T2 DE 69907042 T DE69907042 T DE 69907042T DE 69907042 T DE69907042 T DE 69907042T DE 69907042 T2 DE69907042 T2 DE 69907042T2
Authority
DE
Germany
Prior art keywords
naphthyridones
intermediates
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69907042T
Other languages
English (en)
Other versions
DE69907042D1 (de
Inventor
Charles Kwok-Fung Chiu
Lewin Theophilus Wint
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Products Inc
Original Assignee
Pfizer Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc filed Critical Pfizer Products Inc
Application granted granted Critical
Publication of DE69907042D1 publication Critical patent/DE69907042D1/de
Publication of DE69907042T2 publication Critical patent/DE69907042T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69907042T 1998-01-16 1999-01-12 Ein Verfahren zur Herstellung von Naphthyridonen und Zwischenprodukten Expired - Fee Related DE69907042T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7160198P 1998-01-16 1998-01-16

Publications (2)

Publication Number Publication Date
DE69907042D1 DE69907042D1 (de) 2003-05-28
DE69907042T2 true DE69907042T2 (de) 2003-10-16

Family

ID=22102373

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69907042T Expired - Fee Related DE69907042T2 (de) 1998-01-16 1999-01-12 Ein Verfahren zur Herstellung von Naphthyridonen und Zwischenprodukten

Country Status (39)

Country Link
EP (1) EP0930297B1 (de)
JP (1) JPH11255745A (de)
KR (1) KR19990067905A (de)
CN (1) CN1228422A (de)
AP (1) AP9901440A0 (de)
AR (1) AR017228A1 (de)
AT (1) ATE238281T1 (de)
AU (1) AU9711598A (de)
BG (1) BG64094B1 (de)
BR (1) BR9900066A (de)
CA (1) CA2258960C (de)
DE (1) DE69907042T2 (de)
DK (1) DK0930297T3 (de)
EA (1) EA199900020A3 (de)
EG (1) EG21514A (de)
ES (1) ES2195513T3 (de)
GT (1) GT199800199A (de)
HR (1) HRP990013A2 (de)
HU (1) HUP9900121A3 (de)
ID (1) ID23612A (de)
IL (1) IL127945A0 (de)
IS (1) IS4943A (de)
MA (1) MA24745A1 (de)
NO (1) NO990185L (de)
NZ (1) NZ333769A (de)
OA (1) OA10955A (de)
PA (1) PA8464701A1 (de)
PE (1) PE20000172A1 (de)
PL (1) PL330859A1 (de)
PT (1) PT930297E (de)
SA (1) SA99190971A (de)
SG (1) SG76584A1 (de)
SI (1) SI0930297T1 (de)
SK (1) SK3899A3 (de)
TN (1) TNSN99005A1 (de)
TR (1) TR199900070A3 (de)
TW (1) TW483890B (de)
YU (1) YU1799A (de)
ZA (1) ZA99277B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7019142B2 (en) * 1998-01-16 2006-03-28 Pfizer Inc. Process for preparing naphthyridones and intermediates
HN1999000141A (es) * 1998-09-03 2000-06-19 Pfizer Prod Inc Procedimiento para preparar sales de trovafloxacina de adicion de acidos.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5164402A (en) * 1989-08-16 1992-11-17 Pfizer Inc Azabicyclo quinolone and naphthyridinone carboxylic acids
RU2049777C1 (ru) * 1989-08-16 1995-12-10 Пфайзер Инк. Азабицикло-хинолон-карбоновые кислоты или их фармацевтически приемлемые кислотно-аддитивные соли и промежуточные продукты для их получения
US5256791A (en) * 1992-03-02 1993-10-26 Pfizer Inc. Preparation of intermediates in the synthesis of quinoline antibiotics
US5475116A (en) * 1994-04-29 1995-12-12 Pfizer Inc. Aza bicyclo[3,1,0]hexane intermediates useful in the synthesis of quinolones
DE19733439A1 (de) * 1997-08-02 1999-02-04 Bayer Ag Neue 6-endo-Amino-3-azabicyclo(3.1.0)hexande, Verfahren zu deren Herstellung und deren Verwendung zur Herstellung von Chinolon- und Naphthyridincarbonsäure-Derviaten mit verbesserten Eigenschaften

Also Published As

Publication number Publication date
SI0930297T1 (en) 2003-08-31
DK0930297T3 (da) 2003-07-21
EP0930297A1 (de) 1999-07-21
TNSN99005A1 (fr) 2005-11-10
BG64094B1 (bg) 2003-12-31
CA2258960C (en) 2002-09-03
HU9900121D0 (en) 1999-03-29
NO990185L (no) 1999-07-19
ATE238281T1 (de) 2003-05-15
AP9901440A0 (en) 1999-03-31
SK3899A3 (en) 2000-03-13
HUP9900121A2 (hu) 1999-09-28
AR017228A1 (es) 2001-08-22
NZ333769A (en) 2000-03-27
CA2258960A1 (en) 1999-07-16
ID23612A (id) 2000-05-04
EA199900020A2 (ru) 1999-08-26
EG21514A (en) 2001-11-28
PT930297E (pt) 2003-08-29
OA10955A (en) 2001-10-31
SA99190971A (ar) 2005-12-03
PE20000172A1 (es) 2000-03-09
KR19990067905A (ko) 1999-08-25
GT199800199A (es) 2000-06-07
ES2195513T3 (es) 2003-12-01
IS4943A (is) 1999-07-17
BR9900066A (pt) 2000-05-09
HUP9900121A3 (en) 2000-02-28
YU1799A (sh) 2000-03-21
PA8464701A1 (es) 2000-09-29
EA199900020A3 (ru) 1999-12-29
HRP990013A2 (en) 1999-10-31
TW483890B (en) 2002-04-21
AU9711598A (en) 1999-08-05
CN1228422A (zh) 1999-09-15
IL127945A0 (en) 1999-11-30
JPH11255745A (ja) 1999-09-21
MA24745A1 (fr) 1999-10-01
EP0930297B1 (de) 2003-04-23
SG76584A1 (en) 2000-11-21
PL330859A1 (en) 1999-07-19
NO990185D0 (no) 1999-01-15
DE69907042D1 (de) 2003-05-28
ZA99277B (en) 2000-07-17
BG103087A (en) 1999-08-31
TR199900070A2 (xx) 1999-10-21
TR199900070A3 (tr) 1999-10-21

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee