FI801450A7 - Foerfarande foer framstaellning av 5'-deoxi-5-fluoruridin - Google Patents

Foerfarande foer framstaellning av 5'-deoxi-5-fluoruridin

Info

Publication number
FI801450A7
FI801450A7 FI801450A FI801450A FI801450A7 FI 801450 A7 FI801450 A7 FI 801450A7 FI 801450 A FI801450 A FI 801450A FI 801450 A FI801450 A FI 801450A FI 801450 A7 FI801450 A7 FI 801450A7
Authority
FI
Finland
Prior art keywords
fluoruridine
deoxi
foerfarande foer
foer framstaellning
framstaellning
Prior art date
Application number
FI801450A
Other languages
English (en)
Other versions
FI71566C (fi
FI71566B (fi
Inventor
Sousa Richard D
Joseph Kiss
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of FI801450A7 publication Critical patent/FI801450A7/fi
Application granted granted Critical
Publication of FI71566B publication Critical patent/FI71566B/fi
Publication of FI71566C publication Critical patent/FI71566C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
FI801450A 1979-06-15 1980-05-06 Foerfarande foer framstaellning av 5'- deoxi-5-fluoruridin. FI71566C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH562579 1979-06-15
CH562579 1979-06-15

Publications (3)

Publication Number Publication Date
FI801450A7 true FI801450A7 (fi) 1980-12-16
FI71566B FI71566B (fi) 1986-10-10
FI71566C FI71566C (fi) 1987-01-19

Family

ID=4296736

Family Applications (1)

Application Number Title Priority Date Filing Date
FI801450A FI71566C (fi) 1979-06-15 1980-05-06 Foerfarande foer framstaellning av 5'- deoxi-5-fluoruridin.

Country Status (15)

Country Link
US (1) US4340729A (fi)
EP (1) EP0021231B1 (fi)
JP (2) JPS565497A (fi)
KR (1) KR830001842B1 (fi)
AT (1) ATE4904T1 (fi)
CA (1) CA1135258A (fi)
DE (1) DE3065146D1 (fi)
DK (1) DK148060C (fi)
ES (1) ES492456A0 (fi)
FI (1) FI71566C (fi)
GR (1) GR68760B (fi)
HU (1) HU181712B (fi)
NO (1) NO148109C (fi)
PT (1) PT71382B (fi)
YU (1) YU42664B (fi)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU671491B2 (en) * 1992-12-18 1996-08-29 F. Hoffmann-La Roche Ag N-oxycarbonyl substituted 5'-deoxy-5-fluorcytidines
EP0788507B1 (en) * 1994-10-24 2004-12-15 Genencor International, Inc. L-pyranosyl nucleosides
US5559101A (en) * 1994-10-24 1996-09-24 Genencor International, Inc. L-ribofuranosyl nucleosides
US6593467B2 (en) 1997-05-23 2003-07-15 Clariant Finance (Bvi) Limited Process for the preparation of a deoxyuridine derivative
IT1291983B1 (it) * 1997-05-23 1999-01-25 Pro Bio Sint Srl Prodcedimento per la preparazione di un derivato della desossiuridina
JPH1192386A (ja) * 1997-09-17 1999-04-06 Nikken Chem Co Ltd ５−フルオロウリジン誘導体を有効成分とする抗癌剤
ITMI20032059A1 (it) * 2003-10-22 2005-04-23 Clariant Lsm Italia Spa Processo per la preparazione di doxifluridina.
KR100908363B1 (ko) 2007-02-28 2009-07-20 한미약품 주식회사 트라이-Ｏ-아세틸-5-데옥시-β-Ｄ-라이보퓨라노즈의입체선택적 제조방법 및 이의 분리방법
WO2009044886A1 (ja) 2007-10-05 2009-04-09 Api Corporation リボフラノース誘導体の製造方法
KR101013312B1 (ko) * 2007-11-19 2011-02-09 한미홀딩스 주식회사 카페시타빈의 제조방법 및 이에 사용되는 β-아노머가강화된 트리알킬카보네이트 화합물의 제조방법
AR064165A1 (es) 2007-12-06 2009-03-18 Richmond Sa Com Ind Y Financie Un procedimiento para la preparacion de capecitabina e intermediarios utilizables en dicho procedimiento
EP2210895A1 (en) * 2009-01-27 2010-07-28 F. Hoffmann-La Roche AG Process for the recovery of beta-Acetylfuranoside
CN102260298B (zh) * 2010-05-24 2014-04-09 重庆福安药业(集团)股份有限公司 一种合成1，2，3-O-三乙酰基-5-脱氧-β-D-核糖的方法
CN103772450A (zh) * 2012-10-18 2014-05-07 黑龙江福和华星制药集团股份有限公司 一种1,2,3-三乙酰基-5-脱氧-d-核糖的制法
CN102993254A (zh) * 2012-12-28 2013-03-27 山东铂源药业有限公司 卡培他滨的中间体5′-脱氧-2′,3′-o-异亚丙基-5-氟胞苷的制备方法
CN103232498A (zh) * 2013-05-08 2013-08-07 浙江新三和医药化工股份有限公司 1-甲基-2,3-0-异亚丙基-5-脱氧-d-呋喃核糖的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1812268U (de) 1959-07-03 1960-06-02 Telefunken Gmbh Faraday-isolator.
FR1489919A (fr) 1965-07-22 1967-07-28 Hoffmann La Roche Procédé pour la préparation de nucléosides
DE1812268A1 (de) * 1968-12-03 1970-06-25 Technochemie Gmbh Verfahren zur Herstellung von isomerenfreien hoehermolekularen,sekundaeren Alkylbromiden
JPS52153977A (en) * 1976-06-11 1977-12-21 Daikin Ind Ltd Synthesis of 5-fluorouracil and its derivatives
US4071680A (en) * 1976-12-20 1978-01-31 Hoffmann-La Roche Inc. 5'-Deoxy-5-fluoropyrimidine nucleosides

Also Published As

Publication number Publication date
FI71566C (fi) 1987-01-19
ES8105315A1 (es) 1981-06-01
FI71566B (fi) 1986-10-10
US4340729A (en) 1982-07-20
YU97280A (en) 1983-02-28
JPS632960B2 (fi) 1988-01-21
ES492456A0 (es) 1981-06-01
ATE4904T1 (de) 1983-10-15
HU181712B (en) 1983-11-28
NO801777L (no) 1980-12-16
NO148109B (no) 1983-05-02
JPS59144798A (ja) 1984-08-18
CA1135258A (en) 1982-11-09
DK148060B (da) 1985-02-18
JPS6140239B2 (fi) 1986-09-08
EP0021231A2 (de) 1981-01-07
EP0021231B1 (de) 1983-10-05
KR830002803A (ko) 1983-05-30
DE3065146D1 (en) 1983-11-10
KR830001842B1 (ko) 1983-09-14
GR68760B (fi) 1982-02-17
JPS565497A (en) 1981-01-20
YU42664B (en) 1988-10-31
EP0021231A3 (en) 1981-04-01
DK256380A (da) 1980-12-16
NO148109C (no) 1983-08-10
DK148060C (da) 1985-09-16
PT71382B (en) 1981-10-21
PT71382A (en) 1980-07-01

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Legal Events

Date Code Title Description
MA Patent expired

Owner name: F. HOFFMANN-LA ROCHE AG