FI773073A - Foerfarande foer konversion av transtill cis-n,n-dimetyl-9-(3-(4-metyl-1-piperazinyl)propyliden) tioxanten-2-sulfonamid och tillvaratagande av cis-isomeren - Google Patents

Foerfarande foer konversion av transtill cis-n,n-dimetyl-9-(3-(4-metyl-1-piperazinyl)propyliden) tioxanten-2-sulfonamid och tillvaratagande av cis-isomeren

Info

Publication number
FI773073A
FI773073A FI773073A FI773073A FI773073A FI 773073 A FI773073 A FI 773073A FI 773073 A FI773073 A FI 773073A FI 773073 A FI773073 A FI 773073A FI 773073 A FI773073 A FI 773073A
Authority
FI
Finland
Prior art keywords
transtill
propylides
thioxantene
piperasinyl
sulphonamide
Prior art date
Application number
FI773073A
Other languages
English (en)
Other versions
FI63939C (fi
FI63939B (fi
Inventor
Donald Ernest Kuhla
Harry Austin Watson
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI773073A publication Critical patent/FI773073A/fi
Application granted granted Critical
Publication of FI63939B publication Critical patent/FI63939B/fi
Publication of FI63939C publication Critical patent/FI63939C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/10—Dibenzothiopyrans; Hydrogenated dibenzothiopyrans
    • C07D335/12—Thioxanthenes
    • C07D335/20—Thioxanthenes with hydrocarbon radicals, substituted by amino radicals, directly attached in position 9
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FI773073A 1976-10-20 1977-10-17 Ett nytt foerfarande foer framstaellning av cis-isomeren av n -dimetyl-9-(3-(4-metyl-1-piperazinyl)propyliden)tioxanten -2sulfonamid anvaendbar vid psykoterapi FI63939C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73408176 1976-10-20
US05/734,081 US4107430A (en) 1976-10-20 1976-10-20 Conversion of trans- to cis-N,N-dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]-thioxanthene-2-sulfonamide and recovery of the cis-isomer

Publications (3)

Publication Number Publication Date
FI773073A true FI773073A (fi) 1978-04-21
FI63939B FI63939B (fi) 1983-05-31
FI63939C FI63939C (fi) 1983-09-12

Family

ID=24950235

Family Applications (1)

Application Number Title Priority Date Filing Date
FI773073A FI63939C (fi) 1976-10-20 1977-10-17 Ett nytt foerfarande foer framstaellning av cis-isomeren av n -dimetyl-9-(3-(4-metyl-1-piperazinyl)propyliden)tioxanten -2sulfonamid anvaendbar vid psykoterapi

Country Status (37)

Country Link
US (1) US4107430A (fi)
JP (1) JPS5353674A (fi)
AR (1) AR213867A1 (fi)
AT (1) AT360025B (fi)
AU (1) AU499048B2 (fi)
BE (1) BE859907A (fi)
BG (1) BG32852A3 (fi)
CA (1) CA1085399A (fi)
CH (1) CH625519A5 (fi)
CS (1) CS192494B2 (fi)
DD (1) DD133438A5 (fi)
DE (1) DE2746762C3 (fi)
DK (1) DK159314C (fi)
ES (1) ES463343A1 (fi)
FI (1) FI63939C (fi)
FR (1) FR2368485A1 (fi)
GB (1) GB1542004A (fi)
GR (1) GR69786B (fi)
HK (1) HK31081A (fi)
HU (1) HU173644B (fi)
IE (1) IE45715B1 (fi)
IL (1) IL53056A (fi)
IN (1) IN146954B (fi)
LU (1) LU78336A1 (fi)
MX (1) MX4843E (fi)
MY (1) MY8100275A (fi)
NL (1) NL172062C (fi)
NO (1) NO148713C (fi)
NZ (1) NZ185461A (fi)
PH (1) PH13941A (fi)
PL (1) PL106962B1 (fi)
PT (1) PT67171B (fi)
RO (1) RO74135A (fi)
SE (1) SE437828B (fi)
SU (1) SU831078A3 (fi)
YU (1) YU40978B (fi)
ZA (1) ZA776216B (fi)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2998303B1 (en) 2014-09-17 2018-06-13 B & G Partners, LLC Phenothiazine derivatives and methods for treating tumors
CN107987053B (zh) * 2017-12-08 2023-04-14 植恩生物技术股份有限公司 一种高纯度z型盐酸氟哌噻吨的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3115502A (en) * 1959-06-19 1963-12-24 Hoffmann La Roche Method of isomerizing basically substituted stereoisomeric thioxanthenes
NL103196C (fi) * 1959-06-19
US3310553A (en) * 1962-09-25 1967-03-21 Pfizer & Co C Alkylated thioxathenesulfonamides
US3514449A (en) * 1967-01-16 1970-05-26 Pfizer & Co C Process for separating the cis isomer from a mixture of cis and trans n-(3 - (2 - chlorodibenz(b,e)oxepin - 11(6h)-ylidene)-propyl)piperazine
US3681346A (en) * 1969-06-20 1972-08-01 Kefalas As {60 -isomer of the decanoic acid ester of 10-{8 3,-(4-hydroxyethyl-1-piperazinyl)propylidene{9 -2-trifluoro-methyl thiaxanthene, acid addition salts thereof, method of use and compositions
SU540867A1 (ru) * 1975-06-16 1976-12-30 Предприятие П/Я М-5927 Способ получени цис- -диметил9-/3-(4-метил-1-пиперазинил)-пропилиден/-тиоксантен-2-сульфонамида

Also Published As

Publication number Publication date
FI63939C (fi) 1983-09-12
AR213867A1 (es) 1979-03-30
ZA776216B (en) 1978-06-28
NL172062C (nl) 1983-07-01
PT67171A (pt) 1977-11-01
ATA732077A (de) 1980-05-15
GR69786B (fi) 1982-07-07
SE7710759L (sv) 1978-04-21
BG32852A3 (en) 1982-10-15
FI63939B (fi) 1983-05-31
PT67171B (pt) 1979-03-21
IN146954B (fi) 1979-10-20
LU78336A1 (fr) 1979-06-01
US4107430A (en) 1978-08-15
HU173644B (hu) 1979-07-28
IL53056A (en) 1981-01-30
NO148713B (no) 1983-08-22
MX4843E (es) 1982-10-28
IE45715L (en) 1978-04-20
GB1542004A (en) 1979-03-14
RO74135A (ro) 1981-08-30
YU243877A (en) 1982-08-31
AU499048B2 (en) 1979-04-05
IL53056A0 (en) 1977-12-30
SE437828B (sv) 1985-03-18
NZ185461A (en) 1978-12-18
MY8100275A (en) 1981-12-31
IE45715B1 (en) 1982-11-03
CH625519A5 (fi) 1981-09-30
DE2746762C3 (de) 1980-08-21
HK31081A (en) 1981-07-10
SU831078A3 (ru) 1981-05-15
PL201585A1 (pl) 1978-07-31
FR2368485B1 (fi) 1983-01-07
PL106962B1 (pl) 1980-01-31
BE859907A (fr) 1978-04-19
CS192494B2 (en) 1979-08-31
DK159314C (da) 1991-02-25
JPS6139311B2 (fi) 1986-09-03
DK159314B (da) 1990-10-01
JPS5353674A (en) 1978-05-16
DE2746762B2 (de) 1979-12-13
AT360025B (de) 1980-12-10
NO773588L (no) 1978-04-21
ES463343A1 (es) 1978-07-01
YU40978B (en) 1986-10-31
NO148713C (no) 1983-11-30
FR2368485A1 (fr) 1978-05-19
NL7711471A (nl) 1978-04-24
PH13941A (en) 1980-11-04
DK465377A (da) 1978-04-21
NL172062B (nl) 1983-02-01
CA1085399A (en) 1980-09-09
DD133438A5 (de) 1979-01-03
DE2746762A1 (de) 1978-04-27

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MA Patent expired
MA Patent expired

Owner name: PFIZER INC.