FI782081A - N-substituerade estrar av 9,10-dihydrolyserinsyror och foerfarande foer deras framstaellning - Google Patents

N-substituerade estrar av 9,10-dihydrolyserinsyror och foerfarande foer deras framstaellning

Info

Publication number
FI782081A
FI782081A FI782081A FI782081A FI782081A FI 782081 A FI782081 A FI 782081A FI 782081 A FI782081 A FI 782081A FI 782081 A FI782081 A FI 782081A FI 782081 A FI782081 A FI 782081A
Authority
FI
Finland
Prior art keywords
dihydrolyserinsyror
estrar
substituerade
foerfarande foer
och foerfarande
Prior art date
Application number
FI782081A
Other languages
English (en)
Other versions
FI64369C (fi
FI64369B (fi
Inventor
Rudolf Rucman
Original Assignee
Lek Tovarna Farmacevtskih
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lek Tovarna Farmacevtskih filed Critical Lek Tovarna Farmacevtskih
Publication of FI782081A publication Critical patent/FI782081A/fi
Application granted granted Critical
Publication of FI64369B publication Critical patent/FI64369B/fi
Publication of FI64369C publication Critical patent/FI64369C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI782081A 1977-07-21 1978-06-29 Foerfarande foer framstaellning av n-substituerade estrar av 9,10-dihydrolyserginsyror FI64369C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
YU1819/77A YU40004B (en) 1977-07-21 1977-07-21 Praocess for preparing n-substituted esters of 9,10-dihydrlysergic acid
YU181977 1977-07-21

Publications (3)

Publication Number Publication Date
FI782081A true FI782081A (fi) 1979-01-22
FI64369B FI64369B (fi) 1983-07-29
FI64369C FI64369C (fi) 1983-11-10

Family

ID=25555705

Family Applications (1)

Application Number Title Priority Date Filing Date
FI782081A FI64369C (fi) 1977-07-21 1978-06-29 Foerfarande foer framstaellning av n-substituerade estrar av 9,10-dihydrolyserginsyror

Country Status (11)

Country Link
US (1) US4230859A (fi)
EP (1) EP0000533B1 (fi)
JP (1) JPS5436296A (fi)
AT (1) AT363195B (fi)
CS (1) CS216231B2 (fi)
DE (1) DE2860896D1 (fi)
ES (1) ES471716A1 (fi)
FI (1) FI64369C (fi)
PT (1) PT68278A (fi)
SU (1) SU784775A3 (fi)
YU (1) YU40004B (fi)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4563461A (en) * 1983-03-10 1986-01-07 Eli Lilly And Company Selective method for blocking 5HT2 receptors
FR2584720B1 (fr) * 1985-07-11 1987-10-02 Rhone Poulenc Sante Procede de preparation de derives n-methyles de l'ergoline
FR2584721B1 (fr) * 1985-07-11 1987-10-02 Rhone Poulenc Sante Procede de preparation des derives n-methyles du dihydrolysergate de methyle ou du methoxylumilysergate de methyle
US4906639A (en) * 1985-10-01 1990-03-06 Eli Lilly And Company Cycloalkanol esters of dihydrolysergic acid
US4810710A (en) * 1985-10-01 1989-03-07 Eli Lilly And Company 4-hydroxycyclohexyl 1-isopropyl-9,10-dihydro-lysergate for the treatment of migraine
US4683236A (en) * 1985-10-01 1987-07-28 Eli Lilly And Company Cycloalkanol esters of dihydrolysergic acid useful as 5Ht2 receptor antagonists
US4772709A (en) * 1985-10-01 1988-09-20 Eli Lilly And Company Process of making ketoalkanol esters of dihydrolysergic acid
US4845224A (en) * 1985-10-01 1989-07-04 Eli Lilly And Company Cycloalkanol esters of dihydrolysergic acid having peripheral serotonin antagonist properties
US4847261A (en) * 1985-10-01 1989-07-11 Eli Lilly And Company Alkoxy cycloalkanol esters of dihydrolysergic acid having peripheral serotonin antagonists properties
US4762842A (en) * 1985-10-01 1988-08-09 Eli Lilly And Company Selective method for blocking 5HT2 receptors
US4713384A (en) * 1985-10-01 1987-12-15 Eli Lilly And Company Selective method for blocking 5HT2 receptors
US4968802A (en) * 1985-10-01 1990-11-06 Eli Lilly And Company Process of making alkoxy cycloalkanol esters of dihydrolysergic acid
US4820713A (en) * 1985-10-01 1989-04-11 Eli Lilly And Company Ketoalkanol esters of dihydrolysergic acid useful as 5HT receptor antagonists
US4714704A (en) * 1985-10-01 1987-12-22 Eli Lilly And Company Alkoxy cycloalkanol esters of dihydrolysergic acid useful as 5HT receptor antagonists
US4939258A (en) * 1985-10-01 1990-07-03 Eli Lilly And Company Cycloalkanol esters of dihydrolysergic acid
US4734501A (en) * 1985-10-01 1988-03-29 Eli Lilly And Company N-alkylation of dihydrolysergic acid
US4713385A (en) * 1985-10-01 1987-12-15 Eli Lilly And Company Alkoxy and dialkoxyalkyl esters of dihydrolysergic acid and related compounds useful as 5HT receptor antagonists
US4704395A (en) * 1985-12-20 1987-11-03 Eli Lilly And Company Cyclic ether esters of 2-substituted-6-(substituted and unsubstituted) dihydrolysergic acid useful as 5HT receptor antagonists
US4704396A (en) * 1985-12-20 1987-11-03 Eli Lilly And Company Phenacyl esters of 1-substituted-6-(substituted and unsubstituted) dihydrolysergic acids useful as 5HT receptor antagonists
US4683237A (en) * 1985-12-20 1987-07-28 Eli Lilly And Company Fluoroalkyl esters of dihydrolysergic acid useful as 5HT2 receptor antagonists
US4835159A (en) * 1987-05-11 1989-05-30 Eli Lilly And Company Ergoline esters useful as serotonin antagonists
US4782063A (en) * 1987-05-11 1988-11-01 Eli Lilly And Company Ergoline esters useful as serotonin antagonists
US4981859A (en) * 1987-06-15 1991-01-01 Cycloalkylamides of (8 beta )-1-alkyl-6-(substituted)ergolines
US4931447A (en) * 1987-06-15 1990-06-05 Eli Lilly And Company Cycloalkylamides of (8β)-1-alkyl-6-(substituted) ergolines
JPH01106511U (fi) * 1988-01-02 1989-07-18
JPH02125915U (fi) * 1989-03-29 1990-10-17

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA631701A (en) * 1961-11-28 Sandoz A.G. Compounds of the lysergic acid series alkylated at the indol nitrogen atom
CH344731A (de) * 1956-05-18 1960-02-29 Sandoz Ag Verfahren zur Herstellung von neuen, am Indolstickstoff alkylierten Derivaten der Lysergsäure-Reihe
FR1175276A (fr) * 1956-05-18 1959-03-23 Sandoz Ag Nouveaux dérivés de la série de l'acide lysergique et leur préparation
US3228943A (en) * 1962-06-11 1966-01-11 Lumilysergol derivatives
US3232942A (en) * 1964-06-02 1966-02-01 Sandoz Ltd 1-substituted (+)-lysergol
GB1298277A (en) * 1969-04-18 1972-11-29 Sandoz Ltd Preparation of ergot peptide alkaloids
US3879554A (en) * 1970-03-20 1975-04-22 Farmaceutici Italia Use of 1,6-dimethyl-8-{62 -(5-bromonicotinoyloxymethyl)-10 {60 -methoxyergoline in treating cerebral and peripheral metabolic vascular disorders
NL159384B (nl) * 1971-03-13 1979-02-15 Farmaceutici Italia Werkwijze voor het bereiden van een geneesmiddel met een adrenolytische activiteit, alsmede werkwijze voor het bereiden van een ester van 1-methyl-10-methoxylumilysergol.
GB1413068A (en) * 1972-06-22 1975-11-05 Farmaceutici Italia Bromoergolines

Also Published As

Publication number Publication date
FI64369C (fi) 1983-11-10
EP0000533A1 (de) 1979-02-07
AT363195B (de) 1981-07-10
CS216231B2 (en) 1982-10-29
EP0000533B1 (de) 1981-08-05
JPS5648512B2 (fi) 1981-11-16
US4230859A (en) 1980-10-28
YU40004B (en) 1985-06-30
YU181977A (en) 1983-01-21
ATA490078A (de) 1980-12-15
JPS5436296A (en) 1979-03-16
SU784775A3 (ru) 1980-11-30
ES471716A1 (es) 1979-10-01
PT68278A (en) 1978-08-01
DE2860896D1 (en) 1981-11-05
FI64369B (fi) 1983-07-29

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: LEK TOVARNA FARMACEVTSKIH IN KEMICNIH IZ