YU40978B - Process for obtaining the cis-isomr of n,n-dimethyl-9-(3-(4-methyl-1-piperazinyl)-propylidene)-thioxanthene-2-sulfonamide - Google Patents

Process for obtaining the cis-isomr of n,n-dimethyl-9-(3-(4-methyl-1-piperazinyl)-propylidene)-thioxanthene-2-sulfonamide

Info

Publication number
YU40978B
YU40978B YU2438/77A YU243877A YU40978B YU 40978 B YU40978 B YU 40978B YU 2438/77 A YU2438/77 A YU 2438/77A YU 243877 A YU243877 A YU 243877A YU 40978 B YU40978 B YU 40978B
Authority
YU
Yugoslavia
Prior art keywords
isomr
thioxanthene
propylidene
sulfonamide
piperazinyl
Prior art date
Application number
YU2438/77A
Other languages
English (en)
Other versions
YU243877A (en
Inventor
D E Kuha
H Austin
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of YU243877A publication Critical patent/YU243877A/xx
Publication of YU40978B publication Critical patent/YU40978B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D335/00Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/10Dibenzothiopyrans; Hydrogenated dibenzothiopyrans
    • C07D335/12Thioxanthenes
    • C07D335/20Thioxanthenes with hydrocarbon radicals, substituted by amino radicals, directly attached in position 9
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
YU2438/77A 1976-10-20 1977-10-10 Process for obtaining the cis-isomr of n,n-dimethyl-9-(3-(4-methyl-1-piperazinyl)-propylidene)-thioxanthene-2-sulfonamide YU40978B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/734,081 US4107430A (en) 1976-10-20 1976-10-20 Conversion of trans- to cis-N,N-dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]-thioxanthene-2-sulfonamide and recovery of the cis-isomer

Publications (2)

Publication Number Publication Date
YU243877A YU243877A (en) 1982-08-31
YU40978B true YU40978B (en) 1986-10-31

Family

ID=24950235

Family Applications (1)

Application Number Title Priority Date Filing Date
YU2438/77A YU40978B (en) 1976-10-20 1977-10-10 Process for obtaining the cis-isomr of n,n-dimethyl-9-(3-(4-methyl-1-piperazinyl)-propylidene)-thioxanthene-2-sulfonamide

Country Status (37)

Country Link
US (1) US4107430A (xx)
JP (1) JPS5353674A (xx)
AR (1) AR213867A1 (xx)
AT (1) AT360025B (xx)
AU (1) AU499048B2 (xx)
BE (1) BE859907A (xx)
BG (1) BG32852A3 (xx)
CA (1) CA1085399A (xx)
CH (1) CH625519A5 (xx)
CS (1) CS192494B2 (xx)
DD (1) DD133438A5 (xx)
DE (1) DE2746762C3 (xx)
DK (1) DK159314C (xx)
ES (1) ES463343A1 (xx)
FI (1) FI63939C (xx)
FR (1) FR2368485A1 (xx)
GB (1) GB1542004A (xx)
GR (1) GR69786B (xx)
HK (1) HK31081A (xx)
HU (1) HU173644B (xx)
IE (1) IE45715B1 (xx)
IL (1) IL53056A (xx)
IN (1) IN146954B (xx)
LU (1) LU78336A1 (xx)
MX (1) MX4843E (xx)
MY (1) MY8100275A (xx)
NL (1) NL172062C (xx)
NO (1) NO148713C (xx)
NZ (1) NZ185461A (xx)
PH (1) PH13941A (xx)
PL (1) PL106962B1 (xx)
PT (1) PT67171B (xx)
RO (1) RO74135A (xx)
SE (1) SE437828B (xx)
SU (1) SU831078A3 (xx)
YU (1) YU40978B (xx)
ZA (1) ZA776216B (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2998303B1 (en) 2014-09-17 2018-06-13 B & G Partners, LLC Phenothiazine derivatives and methods for treating tumors
CN107987053B (zh) * 2017-12-08 2023-04-14 植恩生物技术股份有限公司 一种高纯度z型盐酸氟哌噻吨的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3115502A (en) * 1959-06-19 1963-12-24 Hoffmann La Roche Method of isomerizing basically substituted stereoisomeric thioxanthenes
NL103196C (xx) * 1959-06-19
US3310553A (en) * 1962-09-25 1967-03-21 Pfizer & Co C Alkylated thioxathenesulfonamides
US3514449A (en) * 1967-01-16 1970-05-26 Pfizer & Co C Process for separating the cis isomer from a mixture of cis and trans n-(3 - (2 - chlorodibenz(b,e)oxepin - 11(6h)-ylidene)-propyl)piperazine
US3681346A (en) * 1969-06-20 1972-08-01 Kefalas As {60 -isomer of the decanoic acid ester of 10-{8 3,-(4-hydroxyethyl-1-piperazinyl)propylidene{9 -2-trifluoro-methyl thiaxanthene, acid addition salts thereof, method of use and compositions
SU540867A1 (ru) * 1975-06-16 1976-12-30 Предприятие П/Я М-5927 Способ получени цис- -диметил9-/3-(4-метил-1-пиперазинил)-пропилиден/-тиоксантен-2-сульфонамида

Also Published As

Publication number Publication date
BG32852A3 (en) 1982-10-15
AU499048B2 (en) 1979-04-05
AR213867A1 (es) 1979-03-30
CA1085399A (en) 1980-09-09
US4107430A (en) 1978-08-15
PT67171B (pt) 1979-03-21
ATA732077A (de) 1980-05-15
IL53056A0 (en) 1977-12-30
MX4843E (es) 1982-10-28
IE45715L (en) 1978-04-20
SU831078A3 (ru) 1981-05-15
NZ185461A (en) 1978-12-18
IN146954B (xx) 1979-10-20
LU78336A1 (fr) 1979-06-01
JPS5353674A (en) 1978-05-16
PH13941A (en) 1980-11-04
MY8100275A (en) 1981-12-31
PL201585A1 (pl) 1978-07-31
DK465377A (da) 1978-04-21
CS192494B2 (en) 1979-08-31
JPS6139311B2 (xx) 1986-09-03
DK159314B (da) 1990-10-01
DE2746762C3 (de) 1980-08-21
PT67171A (pt) 1977-11-01
NO773588L (no) 1978-04-21
AT360025B (de) 1980-12-10
NL7711471A (nl) 1978-04-24
NL172062C (nl) 1983-07-01
CH625519A5 (xx) 1981-09-30
IL53056A (en) 1981-01-30
FR2368485B1 (xx) 1983-01-07
DK159314C (da) 1991-02-25
YU243877A (en) 1982-08-31
ES463343A1 (es) 1978-07-01
DE2746762B2 (de) 1979-12-13
BE859907A (fr) 1978-04-19
ZA776216B (en) 1978-06-28
HK31081A (en) 1981-07-10
NO148713B (no) 1983-08-22
GR69786B (xx) 1982-07-07
GB1542004A (en) 1979-03-14
NL172062B (nl) 1983-02-01
FI773073A (fi) 1978-04-21
DE2746762A1 (de) 1978-04-27
FI63939B (fi) 1983-05-31
FR2368485A1 (fr) 1978-05-19
DD133438A5 (de) 1979-01-03
HU173644B (hu) 1979-07-28
IE45715B1 (en) 1982-11-03
SE437828B (sv) 1985-03-18
RO74135A (ro) 1981-08-30
PL106962B1 (pl) 1980-01-31
FI63939C (fi) 1983-09-12
NO148713C (no) 1983-11-30
SE7710759L (sv) 1978-04-21

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