FI763158A - - Google Patents

Info

Publication number
FI763158A
FI763158A FI763158A FI763158A FI763158A FI 763158 A FI763158 A FI 763158A FI 763158 A FI763158 A FI 763158A FI 763158 A FI763158 A FI 763158A FI 763158 A FI763158 A FI 763158A
Authority
FI
Finland
Application number
FI763158A
Other languages
Finnish (fi)
Other versions
FI62088C (fi
FI62088B (fi
Inventor
Walter Von Bebenburg
Norbert Schulmeyer
Vladimir Jakovlev
Original Assignee
Degussa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa filed Critical Degussa
Publication of FI763158A publication Critical patent/FI763158A/fi
Application granted granted Critical
Publication of FI62088B publication Critical patent/FI62088B/fi
Publication of FI62088C publication Critical patent/FI62088C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/64One oxygen atom attached in position 2 or 6
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61Halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/70Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI763158A 1975-11-04 1976-11-03 Foerfarande foer framstaellning av farmakodynamiskt verkande 6-fenyl-s-triazolo-(4,3-a)pyrido(2,3-f)(1,4)diazepiner och deas 5-n-oxider samt optiska isomerer och salter FI62088C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT837275A AT350056B (de) 1975-11-04 1975-11-04 Verfahren zur herstellung von neuen pyrido- (2,3-f)-(1,4)-diazepinen, deren optischen isomeren und salzen
AT837275 1975-11-04

Publications (3)

Publication Number Publication Date
FI763158A true FI763158A (fr) 1977-05-05
FI62088B FI62088B (fi) 1982-07-30
FI62088C FI62088C (fi) 1982-11-10

Family

ID=3604891

Family Applications (1)

Application Number Title Priority Date Filing Date
FI763158A FI62088C (fi) 1975-11-04 1976-11-03 Foerfarande foer framstaellning av farmakodynamiskt verkande 6-fenyl-s-triazolo-(4,3-a)pyrido(2,3-f)(1,4)diazepiner och deas 5-n-oxider samt optiska isomerer och salter

Country Status (30)

Country Link
US (1) US4110455A (fr)
JP (1) JPS5831351B2 (fr)
AR (3) AR217814A1 (fr)
AT (1) AT350056B (fr)
AU (1) AU504228B2 (fr)
BE (1) BE847952A (fr)
CA (1) CA1076111A (fr)
CH (1) CH630920A5 (fr)
CS (1) CS191181B2 (fr)
DD (1) DD128178A5 (fr)
DE (1) DE2649116A1 (fr)
DK (1) DK142324B (fr)
EG (1) EG12280A (fr)
ES (2) ES452971A1 (fr)
FI (1) FI62088C (fr)
FR (1) FR2330404A1 (fr)
GB (1) GB1562800A (fr)
HU (1) HU177422B (fr)
IL (1) IL50816A (fr)
IN (1) IN144289B (fr)
MX (1) MX4284E (fr)
NL (1) NL7612187A (fr)
NO (1) NO146470C (fr)
PL (2) PL113803B1 (fr)
PT (1) PT65787B (fr)
RO (2) RO77294A (fr)
SE (1) SE7612260L (fr)
SU (2) SU667137A3 (fr)
YU (1) YU269176A (fr)
ZA (1) ZA766620B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1185601A (fr) * 1981-02-27 1985-04-16 Walter Hunkeler Imidazodiazepines
DE3435973A1 (de) * 1984-10-01 1986-04-10 Boehringer Ingelheim KG, 6507 Ingelheim Diazepine enthaltende pharmazeutische zusammensetzungen mit paf-antagonistischer wirkung
US4798896A (en) * 1988-01-19 1989-01-17 American Home Products Corporation Antipsychotic gamma-carboline N-oxides
US8541407B2 (en) 2010-03-31 2013-09-24 Arqule, Inc. Substituted benzo-pyrido-triazolo-diazepine compounds
AR084070A1 (es) 2010-12-02 2013-04-17 Constellation Pharmaceuticals Inc Inhibidores del bromodominio y usos de los mismos
US9249161B2 (en) 2010-12-02 2016-02-02 Constellation Pharmaceuticals, Inc. Bromodomain inhibitors and uses thereof
US9422292B2 (en) 2011-05-04 2016-08-23 Constellation Pharmaceuticals, Inc. Bromodomain inhibitors and uses thereof
EP2721031B1 (fr) 2011-06-17 2016-01-20 Constellation Pharmaceuticals, Inc. Inhibiteurs à bromodomaine et leurs utilisations
TWI602820B (zh) 2012-06-06 2017-10-21 星宿藥物公司 溴域抑制劑及其用途
EP2864336B1 (fr) 2012-06-06 2016-11-23 Constellation Pharmaceuticals, Inc. Inhibiteurs de bromo-domaine de benzo[b]isoxazoloazépines et applications associées
CA2952830C (fr) 2014-06-20 2022-11-01 Constellation Pharmaceuticals, Inc. Formes cristallines de l'acetamide 2-((4s)-6- (4-chlorophenyl)-1-methyl-4 h-benzo [c] isoxazolo [4s5-e] azepin-4-yle)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT327917B (de) * 1973-04-12 1976-02-25 Degussa Verfahren zur herstellung von neuen 5-aryl-pyrido- (b-6,7) -1,4-diazepinen und deren salzen
US4039551A (en) * 1976-03-15 1977-08-02 The Upjohn Company 1-[(Hydroxyamino)methyl]-6-aryl-4H-s-triazolo[4,3-a][1,4]benzodiazepines

Also Published As

Publication number Publication date
IL50816A (en) 1980-09-16
PL193439A1 (pl) 1979-07-16
GB1562800A (en) 1980-03-19
AT350056B (de) 1979-05-10
EG12280A (en) 1978-12-31
FI62088C (fi) 1982-11-10
SU667137A3 (ru) 1979-06-05
FI62088B (fi) 1982-07-30
FR2330404B1 (fr) 1979-07-20
RO70245A (fr) 1981-06-30
DD128178A5 (de) 1977-11-02
SU676165A3 (ru) 1979-07-25
DK142324C (fr) 1981-03-02
SE7612260L (sv) 1977-05-05
FR2330404A1 (fr) 1977-06-03
US4110455A (en) 1978-08-29
AR217814A1 (es) 1980-04-30
RO77294A (fr) 1982-09-09
AR216916A1 (es) 1980-02-15
JPS5259194A (en) 1977-05-16
PL118308B1 (en) 1981-09-30
MX4284E (es) 1982-03-12
PT65787B (de) 1978-05-10
CS191181B2 (en) 1979-06-29
YU269176A (en) 1983-02-28
AR216915A1 (es) 1980-02-15
ES452969A1 (es) 1977-11-16
PL113803B1 (en) 1981-01-31
CA1076111A (fr) 1980-04-22
CH630920A5 (de) 1982-07-15
AU1931176A (en) 1978-05-11
BE847952A (fr) 1977-05-03
NO146470C (no) 1982-10-06
PT65787A (de) 1976-12-01
JPS5831351B2 (ja) 1983-07-05
DK497076A (fr) 1977-05-05
NO763739L (fr) 1977-05-05
DK142324B (da) 1980-10-13
IN144289B (fr) 1978-04-22
AU504228B2 (en) 1979-10-04
ZA766620B (en) 1977-12-28
DE2649116A1 (de) 1977-05-18
HU177422B (en) 1981-10-28
NL7612187A (nl) 1977-05-06
ATA837275A (de) 1978-10-15
ES452971A1 (es) 1978-10-16
IL50816A0 (en) 1977-01-31
NO146470B (no) 1982-06-28

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: DEGUSSA AKTIENGESELLSCHAFT