SE7612260L - Forfarande for framstellning av nya 6-aryl-s-triazolo-(4,3-a)-pyrido-(2,3-f)-1,4-diazepiner. - Google Patents

Forfarande for framstellning av nya 6-aryl-s-triazolo-(4,3-a)-pyrido-(2,3-f)-1,4-diazepiner.

Info

Publication number
SE7612260L
SE7612260L SE7612260A SE7612260A SE7612260L SE 7612260 L SE7612260 L SE 7612260L SE 7612260 A SE7612260 A SE 7612260A SE 7612260 A SE7612260 A SE 7612260A SE 7612260 L SE7612260 L SE 7612260L
Authority
SE
Sweden
Prior art keywords
atoms
group
hydrogen
alkyl
alkyl group
Prior art date
Application number
SE7612260A
Other languages
English (en)
Swedish (sv)
Inventor
W Von Bebenburg
N Schulmeyer
V Jakovlev
Original Assignee
Degussa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa filed Critical Degussa
Publication of SE7612260L publication Critical patent/SE7612260L/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/70—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
SE7612260A 1975-11-04 1976-11-03 Forfarande for framstellning av nya 6-aryl-s-triazolo-(4,3-a)-pyrido-(2,3-f)-1,4-diazepiner. SE7612260L (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT837275A AT350056B (de) 1975-11-04 1975-11-04 Verfahren zur herstellung von neuen pyrido- (2,3-f)-(1,4)-diazepinen, deren optischen isomeren und salzen

Publications (1)

Publication Number Publication Date
SE7612260L true SE7612260L (sv) 1977-05-05

Family

ID=3604891

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7612260A SE7612260L (sv) 1975-11-04 1976-11-03 Forfarande for framstellning av nya 6-aryl-s-triazolo-(4,3-a)-pyrido-(2,3-f)-1,4-diazepiner.

Country Status (30)

Country Link
US (1) US4110455A (xx)
JP (1) JPS5831351B2 (xx)
AR (3) AR217814A1 (xx)
AT (1) AT350056B (xx)
AU (1) AU504228B2 (xx)
BE (1) BE847952A (xx)
CA (1) CA1076111A (xx)
CH (1) CH630920A5 (xx)
CS (1) CS191181B2 (xx)
DD (1) DD128178A5 (xx)
DE (1) DE2649116A1 (xx)
DK (1) DK142324B (xx)
EG (1) EG12280A (xx)
ES (2) ES452969A1 (xx)
FI (1) FI62088C (xx)
FR (1) FR2330404A1 (xx)
GB (1) GB1562800A (xx)
HU (1) HU177422B (xx)
IL (1) IL50816A (xx)
IN (1) IN144289B (xx)
MX (1) MX4284E (xx)
NL (1) NL7612187A (xx)
NO (1) NO146470C (xx)
PL (2) PL113803B1 (xx)
PT (1) PT65787B (xx)
RO (2) RO77294A (xx)
SE (1) SE7612260L (xx)
SU (2) SU667137A3 (xx)
YU (1) YU269176A (xx)
ZA (1) ZA766620B (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1185601A (en) * 1981-02-27 1985-04-16 Walter Hunkeler Imidazodiazepines
DE3435973A1 (de) * 1984-10-01 1986-04-10 Boehringer Ingelheim KG, 6507 Ingelheim Diazepine enthaltende pharmazeutische zusammensetzungen mit paf-antagonistischer wirkung
US4798896A (en) * 1988-01-19 1989-01-17 American Home Products Corporation Antipsychotic gamma-carboline N-oxides
WO2011123678A2 (en) * 2010-03-31 2011-10-06 Arqule, Inc. Substituted benzo-pyrido-triazolo-diazepine compounds
US9249161B2 (en) 2010-12-02 2016-02-02 Constellation Pharmaceuticals, Inc. Bromodomain inhibitors and uses thereof
AR084070A1 (es) 2010-12-02 2013-04-17 Constellation Pharmaceuticals Inc Inhibidores del bromodominio y usos de los mismos
US9422292B2 (en) 2011-05-04 2016-08-23 Constellation Pharmaceuticals, Inc. Bromodomain inhibitors and uses thereof
WO2012174487A2 (en) 2011-06-17 2012-12-20 Constellation Pharmaceuticals, Inc. Bromodomain inhibitors and uses thereof
EP2864336B1 (en) 2012-06-06 2016-11-23 Constellation Pharmaceuticals, Inc. Benzo[b]isoxazoloazepine bromodomain inhibitors and uses thereof
TWI602820B (zh) 2012-06-06 2017-10-21 星宿藥物公司 溴域抑制劑及其用途
PL3157928T3 (pl) 2014-06-20 2019-07-31 Constellation Pharmaceuticals, Inc. Krystaliczne postacie 2-((4S)-6-(4-chlorofenylo)-1-metylo-4H-benzo[ c]izoksazolo-[4,5-e]azepin-4-ylo)acetamidu

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT327917B (de) * 1973-04-12 1976-02-25 Degussa Verfahren zur herstellung von neuen 5-aryl-pyrido- (b-6,7) -1,4-diazepinen und deren salzen
US4039551A (en) * 1976-03-15 1977-08-02 The Upjohn Company 1-[(Hydroxyamino)methyl]-6-aryl-4H-s-triazolo[4,3-a][1,4]benzodiazepines

Also Published As

Publication number Publication date
AR217814A1 (es) 1980-04-30
HU177422B (en) 1981-10-28
RO70245A (ro) 1981-06-30
AR216915A1 (es) 1980-02-15
GB1562800A (en) 1980-03-19
FI62088C (fi) 1982-11-10
NO146470B (no) 1982-06-28
SU676165A3 (ru) 1979-07-25
NO763739L (xx) 1977-05-05
ES452969A1 (es) 1977-11-16
MX4284E (es) 1982-03-12
FI62088B (fi) 1982-07-30
NL7612187A (nl) 1977-05-06
ZA766620B (en) 1977-12-28
DK497076A (xx) 1977-05-05
AT350056B (de) 1979-05-10
RO77294A (ro) 1982-09-09
PT65787B (de) 1978-05-10
NO146470C (no) 1982-10-06
PL113803B1 (en) 1981-01-31
FI763158A (xx) 1977-05-05
AR216916A1 (es) 1980-02-15
IN144289B (xx) 1978-04-22
ATA837275A (de) 1978-10-15
PL193439A1 (pl) 1979-07-16
YU269176A (en) 1983-02-28
JPS5259194A (en) 1977-05-16
US4110455A (en) 1978-08-29
FR2330404A1 (fr) 1977-06-03
IL50816A (en) 1980-09-16
EG12280A (en) 1978-12-31
BE847952A (fr) 1977-05-03
JPS5831351B2 (ja) 1983-07-05
FR2330404B1 (xx) 1979-07-20
AU1931176A (en) 1978-05-11
CH630920A5 (de) 1982-07-15
CS191181B2 (en) 1979-06-29
AU504228B2 (en) 1979-10-04
PT65787A (de) 1976-12-01
ES452971A1 (es) 1978-10-16
DD128178A5 (de) 1977-11-02
PL118308B1 (en) 1981-09-30
DK142324B (da) 1980-10-13
DK142324C (xx) 1981-03-02
DE2649116A1 (de) 1977-05-18
IL50816A0 (en) 1977-01-31
SU667137A3 (ru) 1979-06-05
CA1076111A (en) 1980-04-22

Similar Documents

Publication Publication Date Title
HUP9900006A2 (hu) Ciklikus GMP-specifikus foszfo-diészteráz inhibitor vegyületek, előállításuk és ezeket tartalmazó gyógyszerkészítmények
SE7612260L (sv) Forfarande for framstellning av nya 6-aryl-s-triazolo-(4,3-a)-pyrido-(2,3-f)-1,4-diazepiner.
ATE94065T1 (de) Diazepine enthaltende pharmazeutische zusammensetzungen mit plaettchen aktivierender faktor (paf)-antagonistischer wirkung.
ES2055056T3 (es) Derivados de pirimidopirimidina.
DK0644883T3 (da) Enniatiner og enniatinderivater til bekæmpelse af endoparasitter
BG60249B2 (en) Thiazole compound for treatment of ulcers
ES8704924A1 (es) Un procedimiento para la preparacion de derivados de benzotiazol y benzotiofeno
NO861621L (no) Analogifremgangsmaate for fremstilling av terapeutisk aktivt 9-(2-fosfonylmethoxyethyl)-adenin
ES8101563A1 (es) Un procedimiento para la preparacion de nuevos derivados he-terociclicos
HUP0000762A2 (hu) 2-Amino-6-(2-szubsztituált-4-fenoxi)piridin-származékok, valamint a vegyületeket tartalmazó gyógyászati készítmények
AR248278A1 (es) Un procedimiento de preparacion de pteridin-4-(3h)-onas, y el procedimiento de sintesis de los intermediarios de aplicacion en dicho procedimiento.
ES2071325T3 (es) Derivados de 4-alquilimidazol.
ATE165972T1 (de) 2(5h)- in position 3-substituierte furanone als ca 2+ antagonisten und entzündungshemmende mittel
HUP9902456A2 (hu) Krománszármazékok és ezeket tartalmazó gyógyászati készítmények
ES8307718A1 (es) "procedimiento de preparar amidoaminoacidos y similares".
NO814299L (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive trisubstituerte pyrimido(5,4-d)pyrimidiner
ES8205204A1 (es) Un procedimiento para la preparacion de derivados de imida- zol
ES457783A1 (es) Procedimiento para la preparacion de nuevos derivados de xantina.
DK624989D0 (da) Hidtil ukendte forbindelser
SE9701682D0 (sv) Compounds
PT900082E (pt) Utilizacao de piridilpiperazina e pirimidilpiperazina para o fabrico de um medicamento para o tratamento de perturbacoes de toxicomania
ES552486A0 (es) Un procedimiento para la obtencion de compuestos de 1-oxa-1-dertia cefalosporina.
ES479110A1 (es) Procedimiento para preparar derivados de benzamidina.
ES8304956A1 (es) Un procedimiento para preparar nuevos derivados de 1,4-benzotiazina.
ATE18993T1 (de) Dibenzocycloheptenyliden-verbindungen zur verwendung bei der modulation der immunreaktion.

Legal Events

Date Code Title Description
NAV Patent application has lapsed

Ref document number: 7612260-5

Format of ref document f/p: F