FI70020C - Som mellanprodukter vid framstaellning av 15-hydroxi-imino-e-homoeburnanderivat anvaendbara 15-halogen-e-homoeburnanderivat foerfarande foer deras framstaellning och deras anvaendning - Google Patents
Som mellanprodukter vid framstaellning av 15-hydroxi-imino-e-homoeburnanderivat anvaendbara 15-halogen-e-homoeburnanderivat foerfarande foer deras framstaellning och deras anvaendning Download PDFInfo
- Publication number
- FI70020C FI70020C FI802175A FI802175A FI70020C FI 70020 C FI70020 C FI 70020C FI 802175 A FI802175 A FI 802175A FI 802175 A FI802175 A FI 802175A FI 70020 C FI70020 C FI 70020C
- Authority
- FI
- Finland
- Prior art keywords
- halogen
- homoeburnanderivat
- epimers
- general formula
- framstaellning
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Claims (4)
1. Som mellanprodukter vid framställning av 15-hydroxi-imino-E-homoeburnanderivat användbara 15—halogen-E-homoeburnanderivat med den allmänna formeln (III) K/J 2.ΛΓ * X H 1 2 väri R är C^^-alkyl, X är väte eller halogen och X är halogen, samt epimerer, syraadditionssalter och optiskt aktiva derivat därav.
2. (+)-3(S), 17(S)-11-brom-14-oxo-l5-klor-E-homoeburnan och 15-epimerer därav.
3. Förfarande för framställning av 15 halogen-E-homoeburnan-derivat med den allmänna formeln (III), väri R är C. ,-alkyl, och 2 1 -b X är halogen, samt epimerer, syraadditionssalter eller optiskt aktiva derivat därav, kännetecknat därav, att man be-handlar ett racemiskt eller optiskt aktivt 15-hydroxi-E-homoeburnan-derivat med den allmänna formeln (II) (II) A7 * OH ^ 1 väri R och X betecknar samma som ovan, eventuellt efter separation av 15-epimerer och/eller upplösning, med ett halogeneringsmedel, och ifall önskvärt, omvandlar den erhällna racemiska eller optiskt aktiva föreningen med den allmänna formeln (III) tili ett syraad-ditionssalt, upplöser och/eller separerar 15-epimerer.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HURI000719 | 1979-07-13 | ||
| HU79RI719A HU180927B (en) | 1979-07-13 | 1979-07-13 | Process for producing 1k-hydroximino-e-homoe-eburane de rivatives |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI802175A FI802175A (fi) | 1981-01-14 |
| FI70020B FI70020B (fi) | 1986-01-31 |
| FI70020C true FI70020C (fi) | 1986-09-12 |
Family
ID=11001102
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI802175A FI70020C (fi) | 1979-07-13 | 1980-07-07 | Som mellanprodukter vid framstaellning av 15-hydroxi-imino-e-homoeburnanderivat anvaendbara 15-halogen-e-homoeburnanderivat foerfarande foer deras framstaellning och deras anvaendning |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US4314939A (sv) |
| JP (2) | JPS595595B2 (sv) |
| AT (1) | AT375939B (sv) |
| AU (1) | AU534308B2 (sv) |
| BE (1) | BE884228A (sv) |
| CA (1) | CA1137083A (sv) |
| CH (1) | CH644122A5 (sv) |
| DE (1) | DE3026602A1 (sv) |
| DK (1) | DK156574C (sv) |
| ES (1) | ES8106727A1 (sv) |
| FI (1) | FI70020C (sv) |
| FR (1) | FR2460951A1 (sv) |
| GB (1) | GB2055368B (sv) |
| HU (1) | HU180927B (sv) |
| IL (1) | IL60445A (sv) |
| IT (1) | IT1132528B (sv) |
| NL (1) | NL8003822A (sv) |
| NO (1) | NO802101L (sv) |
| NZ (1) | NZ194316A (sv) |
| PH (1) | PH15654A (sv) |
| SE (1) | SE438504B (sv) |
| SU (1) | SU982541A3 (sv) |
| ZA (1) | ZA803952B (sv) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU181496B (en) * | 1979-08-13 | 1983-07-28 | Richter Gedeon Vegyeszet | Process for preparing 10-bromo-15-hydroxy-e-homo-eburnanes |
| HU182411B (en) * | 1981-11-03 | 1984-01-30 | Richter Gedeon Vegyeszet | Process for preparing eburnamonine derivatives |
| HU186891B (en) * | 1981-06-12 | 1985-10-28 | Richter Gedeon Vegyeszet | Process for producing esters of apovincaminic acid |
| HU182380B (en) * | 1981-09-30 | 1983-12-28 | Richter Gedeon Vegyeszet | Process for producing esters of vincaminic acid |
| HU185172B (en) * | 1981-12-30 | 1984-12-28 | Richter Gedeon Vegyeszet | Process for the preparation of hydroxy-imino-e-homo-eburnanes |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU180514B (hu) * | 1977-05-26 | 1983-03-28 | Richter Gedeon Vegyeszet | Eljárás apovinkaminsav-észterek, illetve vinkaminsav-észterek és apovinkaminsavészterek egyidejű előállítására |
| HU180928B (en) * | 1979-08-06 | 1983-05-30 | Richter Gedeon Vegyeszet | Process for preparing new brominated 15-hydroxy-e-homo-eburane derivatives |
| HU181496B (en) * | 1979-08-13 | 1983-07-28 | Richter Gedeon Vegyeszet | Process for preparing 10-bromo-15-hydroxy-e-homo-eburnanes |
-
1979
- 1979-07-13 HU HU79RI719A patent/HU180927B/hu not_active IP Right Cessation
-
1980
- 1980-06-30 IL IL60445A patent/IL60445A/xx unknown
- 1980-07-01 ZA ZA00803952A patent/ZA803952B/xx unknown
- 1980-07-02 NL NL8003822A patent/NL8003822A/nl not_active Application Discontinuation
- 1980-07-07 FI FI802175A patent/FI70020C/fi not_active IP Right Cessation
- 1980-07-09 BE BE1/9892A patent/BE884228A/fr not_active IP Right Cessation
- 1980-07-09 PH PH24262A patent/PH15654A/en unknown
- 1980-07-10 FR FR8015361A patent/FR2460951A1/fr active Granted
- 1980-07-10 AT AT0358880A patent/AT375939B/de not_active IP Right Cessation
- 1980-07-10 GB GB8022561A patent/GB2055368B/en not_active Expired
- 1980-07-11 ES ES493336A patent/ES8106727A1/es not_active Expired
- 1980-07-11 CH CH534080A patent/CH644122A5/de not_active IP Right Cessation
- 1980-07-11 IT IT23404/80A patent/IT1132528B/it active
- 1980-07-11 AU AU60350/80A patent/AU534308B2/en not_active Ceased
- 1980-07-11 NO NO802101A patent/NO802101L/no unknown
- 1980-07-11 CA CA000355991A patent/CA1137083A/en not_active Expired
- 1980-07-11 SE SE8005127A patent/SE438504B/sv not_active IP Right Cessation
- 1980-07-11 SU SU802949854A patent/SU982541A3/ru active
- 1980-07-11 DK DK302280A patent/DK156574C/da not_active IP Right Cessation
- 1980-07-11 NZ NZ194316A patent/NZ194316A/xx unknown
- 1980-07-12 JP JP55094575A patent/JPS595595B2/ja not_active Expired
- 1980-07-14 DE DE19803026602 patent/DE3026602A1/de active Granted
- 1980-07-14 US US06/168,560 patent/US4314939A/en not_active Expired - Lifetime
-
1983
- 1983-07-01 JP JP58120151A patent/JPS59116285A/ja active Granted
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM | Patent lapsed |
Owner name: RICHTER GEDEON VEGYESZETI GYAR R.T. |