FI68399C - Foerfarande foer framstaellning av terapeutiskt aktiva 2-amino-3-nitropyrrolderivat - Google Patents

Foerfarande foer framstaellning av terapeutiskt aktiva 2-amino-3-nitropyrrolderivat Download PDF

Info

Publication number
FI68399C
FI68399C FI791738A FI791738A FI68399C FI 68399 C FI68399 C FI 68399C FI 791738 A FI791738 A FI 791738A FI 791738 A FI791738 A FI 791738A FI 68399 C FI68399 C FI 68399C
Authority
FI
Finland
Prior art keywords
het
methyl
nitro
nitropyrrole
alkyl
Prior art date
Application number
FI791738A
Other languages
English (en)
Finnish (fi)
Other versions
FI791738A (fi
FI68399B (fi
Inventor
Michael Laurence Roantree
Rodney Christopher Young
Original Assignee
Smith Kline French Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab
Publication of FI791738A publication Critical patent/FI791738A/fi
Application granted granted Critical
Publication of FI68399B publication Critical patent/FI68399B/fi
Publication of FI68399C publication Critical patent/FI68399C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/42—Nitro radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI791738A 1978-05-30 1979-05-30 Foerfarande foer framstaellning av terapeutiskt aktiva 2-amino-3-nitropyrrolderivat FI68399C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB2411778 1978-05-30
GB2411778 1978-05-30
GB7832313 1978-08-04
GB7832313 1978-08-04

Publications (3)

Publication Number Publication Date
FI791738A FI791738A (fi) 1979-12-01
FI68399B FI68399B (fi) 1985-05-31
FI68399C true FI68399C (fi) 1985-09-10

Family

ID=26256929

Family Applications (1)

Application Number Title Priority Date Filing Date
FI791738A FI68399C (fi) 1978-05-30 1979-05-30 Foerfarande foer framstaellning av terapeutiskt aktiva 2-amino-3-nitropyrrolderivat

Country Status (19)

Country Link
US (4) US4238494A (fr)
EP (1) EP0005985B1 (fr)
AR (1) AR225285A1 (fr)
AU (1) AU521405B2 (fr)
CA (1) CA1124719A (fr)
DD (1) DD144056A5 (fr)
DE (1) DE2965270D1 (fr)
DK (1) DK224079A (fr)
ES (1) ES481119A1 (fr)
FI (1) FI68399C (fr)
GR (1) GR68026B (fr)
IE (1) IE48756B1 (fr)
IL (1) IL57415A (fr)
NO (1) NO151008C (fr)
PH (1) PH18500A (fr)
PL (1) PL115380B1 (fr)
PT (1) PT69687A (fr)
RO (1) RO77448A (fr)
YU (1) YU127279A (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL57415A (en) * 1978-05-30 1984-08-31 Smith Kline French Lab Nitropyrrole compounds,process for preparing them and pharmaceutical compositions containing them
US4359466A (en) * 1979-10-24 1982-11-16 Smith Kline & French Laboratories Limited Guanidine compounds
EP0089153B1 (fr) * 1982-03-17 1986-09-24 Smith Kline & French Laboratories Limited Dérivés de pyridine
AU2222083A (en) * 1982-12-14 1984-06-21 Smith Kline & French Laboratories Limited Pyridine derivatives
JPH0615527B2 (ja) * 1983-01-21 1994-03-02 アルカロイダ ベギエスゼテイ ギヤル アルキルジアミン誘導体、その製造法および抗不整脈剤
US4624958A (en) * 1983-04-14 1986-11-25 Pfizer Inc. Antiprotozoal 1,4-di(p-amidinophenyl)imidazoles
JP3923079B2 (ja) * 1995-07-31 2007-05-30 塩野義製薬株式会社 ホスホリパーゼａ２阻害活性を有するピロリジン誘導体
WO2022034121A1 (fr) 2020-08-11 2022-02-17 Université De Strasbourg Bloqueurs de h2 ciblant des macrophages du foie pour la prévention et le traitement d'une maladie du foie et du cancer

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3518251A (en) * 1967-06-07 1970-06-30 Geigy Ag J R Certain aminoalkylamino substituted azacycloalkenes
GB1305550A (fr) * 1969-10-29 1973-02-07
US3734924A (en) * 1970-10-14 1973-05-22 Smith Kline French Lab Carboxamidines
GB1400319A (en) * 1972-04-20 1975-07-16 Smith Kline French Lab Pharmaceutical compositions
GB1419994A (en) * 1973-05-03 1976-01-07 Smith Kline French Lab Heterocyclicalkylaminotheterocyclic compounds methods for their preparation and compositions comprising them
GB1421792A (en) * 1973-05-17 1976-01-21 Smith Kline French Lab Heterocyclic substituted-1, 1-diamino-ethylene derivatives methods for their preparation and compositions containing them
GB1496787A (en) * 1974-03-12 1978-01-05 Smith Kline French Lab Heteroalkylthioalkyl amidine derivatives
IL49528A (en) * 1975-05-21 1980-11-30 Smith Kline French Lab Imidazolyl(or thiazolyl)methylthio(or butyl)guanidine or thiourea derivatives,their preparation and pharmaceutical compositions comprising them
GB1563090A (en) * 1975-07-31 1980-03-19 Smith Kline French Lab Cyclobutene-diones
US4154834A (en) * 1975-12-29 1979-05-15 Smith Kline & French Laboratories Limited Substituted isocytosines having histamine H2 -antagonist activity
GB1574214A (en) * 1976-03-11 1980-09-03 Smith Kline French Lab Amidines
GB1565966A (en) * 1976-08-04 1980-04-23 Allen & Hanburys Ltd Aminoalkyl furan derivatives
DE2645172C2 (de) * 1976-10-07 1982-02-18 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von 4-Nitroimidazolen
DK168277A (da) * 1977-02-22 1978-08-23 Smithkline Corp Fremgangsmaade til fremstilling af 4-substituerede imidazolforbindelser
IN151188B (fr) * 1978-02-13 1983-03-05 Smith Kline French Lab
IL57415A (en) * 1978-05-30 1984-08-31 Smith Kline French Lab Nitropyrrole compounds,process for preparing them and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
EP0005985A1 (fr) 1979-12-12
IE48756B1 (en) 1985-05-15
US4238494A (en) 1980-12-09
IL57415A0 (en) 1979-09-30
GR68026B (fr) 1981-10-27
DD144056A5 (de) 1980-09-24
AR225285A1 (es) 1982-03-15
AU521405B2 (en) 1982-04-01
US4331668A (en) 1982-05-25
PH18500A (en) 1985-08-02
PL115380B1 (en) 1981-03-31
CA1124719A (fr) 1982-06-01
NO151008B (no) 1984-10-15
PT69687A (en) 1979-06-01
AU4758179A (en) 1979-12-06
DK224079A (da) 1979-12-01
IE791101L (en) 1979-11-30
FI791738A (fi) 1979-12-01
DE2965270D1 (en) 1983-06-01
PL215971A1 (fr) 1980-02-11
US4482563A (en) 1984-11-13
ES481119A1 (es) 1980-09-01
FI68399B (fi) 1985-05-31
YU127279A (en) 1983-04-30
EP0005985B1 (fr) 1983-04-27
US4407808A (en) 1983-10-04
RO77448A (fr) 1981-11-04
NO151008C (no) 1985-01-23
NO791764L (no) 1979-12-03
IL57415A (en) 1984-08-31

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Date Code Title Description
MM Patent lapsed

Owner name: SMITH KLINE & FRENCH LABORATORIES