FI67375C - Foerfarande foer framstaellning av 3-hydroxi-1,4-benzodiazepin-2-oner - Google Patents

Foerfarande foer framstaellning av 3-hydroxi-1,4-benzodiazepin-2-oner Download PDF

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Publication number
FI67375C
FI67375C FI793924A FI793924A FI67375C FI 67375 C FI67375 C FI 67375C FI 793924 A FI793924 A FI 793924A FI 793924 A FI793924 A FI 793924A FI 67375 C FI67375 C FI 67375C
Authority
FI
Finland
Prior art keywords
halogen
benzodiazepin
hydroxy
compounds
general formula
Prior art date
Application number
FI793924A
Other languages
English (en)
Finnish (fi)
Other versions
FI793924A7 (fi
FI67375B (fi
Inventor
Ludwig H Schlager
Original Assignee
Gerot Pharmazeutika
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gerot Pharmazeutika filed Critical Gerot Pharmazeutika
Publication of FI793924A7 publication Critical patent/FI793924A7/fi
Application granted granted Critical
Publication of FI67375B publication Critical patent/FI67375B/fi
Publication of FI67375C publication Critical patent/FI67375C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Anesthesiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI793924A 1978-12-18 1979-12-14 Foerfarande foer framstaellning av 3-hydroxi-1,4-benzodiazepin-2-oner FI67375C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT903178A AT361492B (de) 1978-12-18 1978-12-18 Verfahren zur herstellung von neuen 3-hydroxy- 1,4-benzodiazepin-2-onen
AT903178 1978-12-18

Publications (3)

Publication Number Publication Date
FI793924A7 FI793924A7 (fi) 1980-06-19
FI67375B FI67375B (fi) 1984-11-30
FI67375C true FI67375C (fi) 1985-03-11

Family

ID=3610590

Family Applications (1)

Application Number Title Priority Date Filing Date
FI793924A FI67375C (fi) 1978-12-18 1979-12-14 Foerfarande foer framstaellning av 3-hydroxi-1,4-benzodiazepin-2-oner

Country Status (25)

Country Link
US (1) US4388313A (https=)
JP (1) JPS5583764A (https=)
AT (1) AT361492B (https=)
AU (1) AU532331B2 (https=)
BE (1) BE880632A (https=)
BG (1) BG60474B2 (https=)
CA (1) CA1113464A (https=)
CH (1) CH643248A5 (https=)
DE (1) DE2950235A1 (https=)
DK (1) DK154973C (https=)
ES (1) ES8103738A1 (https=)
FI (1) FI67375C (https=)
FR (1) FR2444672A1 (https=)
GB (1) GB2043630B (https=)
GR (1) GR73901B (https=)
HK (1) HK33385A (https=)
IT (1) IT1193345B (https=)
LU (1) LU81990A1 (https=)
MY (1) MY8600020A (https=)
NL (1) NL187068C (https=)
NO (1) NO151859C (https=)
SE (1) SE440351B (https=)
SG (1) SG13585G (https=)
YU (1) YU40586B (https=)
ZA (1) ZA796600B (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2084577T3 (es) * 1986-10-24 1996-05-16 Abbott Lab Ensayo, trazadores, inmunogenos y anticuerpos para benzodiazepinas.

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3311612A (en) * 1967-03-28 Process for preparing
US3371085A (en) * 1959-12-10 1968-02-27 Hoffmann La Roche 5-aryl-3h-1,4-benzodiazepin-2(1h)-ones
BE621819A (https=) * 1961-08-29
GB1050401A (https=) * 1963-02-19 1900-01-01
NL298071A (https=) * 1963-06-04
GB1051795A (https=) * 1964-02-11
FR135F (https=) * 1964-08-13
NO120269B (https=) * 1965-11-02 1970-09-28 Hoffmann La Roche
US3464978A (en) * 1967-04-21 1969-09-02 Hoffmann La Roche 1-substituted urea alkyl 1,2-dihydro-1,4-benzodiazepines and benzodiazepin - 2-ones
CH574421A5 (en) * 1969-02-14 1976-04-15 Hoffmann La Roche Benzodiazepines
AT309436B (de) * 1970-06-23 1973-08-27 Gerot Pharmazeutika Verfahren zur Herstellung von 3-Hydroxy-1,4-benzodiazepin Derivaten oder deren Salzen
US4065451A (en) * 1971-03-30 1977-12-27 American Home Products 1,3-Dihydro-3-hydroxy-5-phenyl-2H-1,4-benzodiazepin-2-one, substituted diamino acetate esters and their acid salts
CH573416A5 (https=) * 1971-07-30 1976-03-15 Sumitomo Chemical Co
US3801568A (en) * 1972-02-07 1974-04-02 American Home Prod Optically active 1,3-dihydro-3-substituted 5-phenyl-2h-1,4-benzodiazepin-2-ones and process for their separation
JPS494226A (https=) * 1972-04-27 1974-01-16

Also Published As

Publication number Publication date
NO151859C (no) 1985-06-19
YU308779A (en) 1983-02-28
GR73901B (https=) 1984-05-18
NO793827L (no) 1980-06-19
NL7908919A (nl) 1980-06-20
FR2444672A1 (fr) 1980-07-18
JPS5583764A (en) 1980-06-24
FI793924A7 (fi) 1980-06-19
JPS6310699B2 (https=) 1988-03-08
CH643248A5 (de) 1984-05-30
GB2043630B (en) 1983-06-15
HK33385A (en) 1985-05-10
SG13585G (en) 1985-08-16
GB2043630A (en) 1980-10-08
FR2444672B1 (https=) 1983-05-13
NL187068B (nl) 1990-12-17
ES486895A0 (es) 1980-10-01
AU532331B2 (en) 1983-09-29
SE440351B (sv) 1985-07-29
MY8600020A (en) 1986-12-31
NO151859B (no) 1985-03-11
ZA796600B (en) 1981-07-29
AU5366479A (en) 1980-06-26
DE2950235C2 (https=) 1987-08-27
YU40586B (en) 1986-02-28
IT7928149A0 (it) 1979-12-18
SE7910333L (sv) 1980-06-19
DK154973C (da) 1989-06-05
IT1193345B (it) 1988-06-15
NL187068C (nl) 1991-05-16
BG60474B2 (bg) 1995-04-28
BE880632A (fr) 1980-06-16
ATA903178A (de) 1980-08-15
LU81990A1 (fr) 1981-07-23
DK154973B (da) 1989-01-16
AT361492B (de) 1981-03-10
DK510379A (da) 1980-06-19
FI67375B (fi) 1984-11-30
US4388313A (en) 1983-06-14
CA1113464A (en) 1981-12-01
DE2950235A1 (de) 1980-06-26
ES8103738A1 (es) 1980-10-01

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MA Patent expired

Owner name: GEROT PHARMAZEUTIKA GESELLSCHAFT M.B.H