ZA796600B - Novel 3-hydroxy-1, 4-benzodiazepine-2-ones and process for the preparation thereof - Google Patents

Novel 3-hydroxy-1, 4-benzodiazepine-2-ones and process for the preparation thereof

Info

Publication number
ZA796600B
ZA796600B ZA00796600A ZA796600A ZA796600B ZA 796600 B ZA796600 B ZA 796600B ZA 00796600 A ZA00796600 A ZA 00796600A ZA 796600 A ZA796600 A ZA 796600A ZA 796600 B ZA796600 B ZA 796600B
Authority
ZA
South Africa
Prior art keywords
benzodiazepine
hydroxy
ones
novel
preparation
Prior art date
Application number
ZA00796600A
Other languages
English (en)
Inventor
L Schlager
Original Assignee
Gerot Pharmazeutika
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gerot Pharmazeutika filed Critical Gerot Pharmazeutika
Publication of ZA796600B publication Critical patent/ZA796600B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Anesthesiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA00796600A 1978-12-18 1979-12-05 Novel 3-hydroxy-1, 4-benzodiazepine-2-ones and process for the preparation thereof ZA796600B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT903178A AT361492B (de) 1978-12-18 1978-12-18 Verfahren zur herstellung von neuen 3-hydroxy- 1,4-benzodiazepin-2-onen

Publications (1)

Publication Number Publication Date
ZA796600B true ZA796600B (en) 1981-07-29

Family

ID=3610590

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00796600A ZA796600B (en) 1978-12-18 1979-12-05 Novel 3-hydroxy-1, 4-benzodiazepine-2-ones and process for the preparation thereof

Country Status (25)

Country Link
US (1) US4388313A (https=)
JP (1) JPS5583764A (https=)
AT (1) AT361492B (https=)
AU (1) AU532331B2 (https=)
BE (1) BE880632A (https=)
BG (1) BG60474B2 (https=)
CA (1) CA1113464A (https=)
CH (1) CH643248A5 (https=)
DE (1) DE2950235A1 (https=)
DK (1) DK154973C (https=)
ES (1) ES8103738A1 (https=)
FI (1) FI67375C (https=)
FR (1) FR2444672A1 (https=)
GB (1) GB2043630B (https=)
GR (1) GR73901B (https=)
HK (1) HK33385A (https=)
IT (1) IT1193345B (https=)
LU (1) LU81990A1 (https=)
MY (1) MY8600020A (https=)
NL (1) NL187068C (https=)
NO (1) NO151859C (https=)
SE (1) SE440351B (https=)
SG (1) SG13585G (https=)
YU (1) YU40586B (https=)
ZA (1) ZA796600B (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2084577T3 (es) * 1986-10-24 1996-05-16 Abbott Lab Ensayo, trazadores, inmunogenos y anticuerpos para benzodiazepinas.

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3311612A (en) * 1967-03-28 Process for preparing
US3371085A (en) * 1959-12-10 1968-02-27 Hoffmann La Roche 5-aryl-3h-1,4-benzodiazepin-2(1h)-ones
BE621819A (https=) * 1961-08-29
GB1050401A (https=) * 1963-02-19 1900-01-01
NL298071A (https=) * 1963-06-04
GB1051795A (https=) * 1964-02-11
FR135F (https=) * 1964-08-13
NO120269B (https=) * 1965-11-02 1970-09-28 Hoffmann La Roche
US3464978A (en) * 1967-04-21 1969-09-02 Hoffmann La Roche 1-substituted urea alkyl 1,2-dihydro-1,4-benzodiazepines and benzodiazepin - 2-ones
CH574421A5 (en) * 1969-02-14 1976-04-15 Hoffmann La Roche Benzodiazepines
AT309436B (de) * 1970-06-23 1973-08-27 Gerot Pharmazeutika Verfahren zur Herstellung von 3-Hydroxy-1,4-benzodiazepin Derivaten oder deren Salzen
US4065451A (en) * 1971-03-30 1977-12-27 American Home Products 1,3-Dihydro-3-hydroxy-5-phenyl-2H-1,4-benzodiazepin-2-one, substituted diamino acetate esters and their acid salts
CH573416A5 (https=) * 1971-07-30 1976-03-15 Sumitomo Chemical Co
US3801568A (en) * 1972-02-07 1974-04-02 American Home Prod Optically active 1,3-dihydro-3-substituted 5-phenyl-2h-1,4-benzodiazepin-2-ones and process for their separation
JPS494226A (https=) * 1972-04-27 1974-01-16

Also Published As

Publication number Publication date
NO151859C (no) 1985-06-19
YU308779A (en) 1983-02-28
GR73901B (https=) 1984-05-18
NO793827L (no) 1980-06-19
NL7908919A (nl) 1980-06-20
FR2444672A1 (fr) 1980-07-18
JPS5583764A (en) 1980-06-24
FI793924A7 (fi) 1980-06-19
JPS6310699B2 (https=) 1988-03-08
CH643248A5 (de) 1984-05-30
GB2043630B (en) 1983-06-15
HK33385A (en) 1985-05-10
SG13585G (en) 1985-08-16
GB2043630A (en) 1980-10-08
FR2444672B1 (https=) 1983-05-13
NL187068B (nl) 1990-12-17
ES486895A0 (es) 1980-10-01
AU532331B2 (en) 1983-09-29
SE440351B (sv) 1985-07-29
MY8600020A (en) 1986-12-31
NO151859B (no) 1985-03-11
AU5366479A (en) 1980-06-26
DE2950235C2 (https=) 1987-08-27
YU40586B (en) 1986-02-28
IT7928149A0 (it) 1979-12-18
SE7910333L (sv) 1980-06-19
DK154973C (da) 1989-06-05
IT1193345B (it) 1988-06-15
NL187068C (nl) 1991-05-16
BG60474B2 (bg) 1995-04-28
BE880632A (fr) 1980-06-16
ATA903178A (de) 1980-08-15
FI67375C (fi) 1985-03-11
LU81990A1 (fr) 1981-07-23
DK154973B (da) 1989-01-16
AT361492B (de) 1981-03-10
DK510379A (da) 1980-06-19
FI67375B (fi) 1984-11-30
US4388313A (en) 1983-06-14
CA1113464A (en) 1981-12-01
DE2950235A1 (de) 1980-06-26
ES8103738A1 (es) 1980-10-01

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