FI66864C - Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 4-oxo-4h-pyrido(1,2-a)pyrimidinderivat - Google Patents

Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 4-oxo-4h-pyrido(1,2-a)pyrimidinderivat Download PDF

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Publication number
FI66864C
FI66864C FI782527A FI782527A FI66864C FI 66864 C FI66864 C FI 66864C FI 782527 A FI782527 A FI 782527A FI 782527 A FI782527 A FI 782527A FI 66864 C FI66864 C FI 66864C
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FI
Finland
Prior art keywords
ethyl
oxo
pyrido
pyrimidine
methyl
Prior art date
Application number
FI782527A
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English (en)
Finnish (fi)
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FI66864B (fi
FI782527A (fi
Inventor
Jozsef Knoll
Zoltan Meszaros
Istvan Hermecz
Ferenc Fueloep
Gabor Bernath
Sandor Virag
Gabor Nagy
Peter Szentmiklosi
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of FI782527A publication Critical patent/FI782527A/fi
Application granted granted Critical
Publication of FI66864B publication Critical patent/FI66864B/fi
Publication of FI66864C publication Critical patent/FI66864C/fi

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI782527A 1977-08-19 1978-08-18 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 4-oxo-4h-pyrido(1,2-a)pyrimidinderivat FI66864C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HUCI001765 1977-08-19
HU77CI1765A HU178910B (en) 1977-08-19 1977-08-19 Process for preparing 2,3-disubstituted-4-oxo-4h-pyrido/1,2-a/-pyrimidines

Publications (3)

Publication Number Publication Date
FI782527A FI782527A (fi) 1979-02-20
FI66864B FI66864B (fi) 1984-08-31
FI66864C true FI66864C (fi) 1984-12-10

Family

ID=10994667

Family Applications (1)

Application Number Title Priority Date Filing Date
FI782527A FI66864C (fi) 1977-08-19 1978-08-18 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 4-oxo-4h-pyrido(1,2-a)pyrimidinderivat

Country Status (22)

Country Link
US (2) US4219649A (el)
JP (1) JPS5448795A (el)
AT (1) AT368156B (el)
AU (1) AU518364B2 (el)
BE (1) BE869832A (el)
CA (1) CA1152989A (el)
CH (1) CH637541A5 (el)
CS (1) CS238901B1 (el)
DD (1) DD138320A5 (el)
DE (1) DE2835004A1 (el)
DK (1) DK160045C (el)
ES (1) ES473181A1 (el)
FI (1) FI66864C (el)
FR (1) FR2416892A1 (el)
GB (1) GB2006187B (el)
GR (1) GR64913B (el)
HU (1) HU178910B (el)
IL (1) IL55338A (el)
NL (1) NL7808570A (el)
SE (1) SE435383B (el)
SU (1) SU906378A3 (el)
YU (1) YU40985B (el)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU179143B (en) * 1977-12-29 1982-08-28 Chinoin Gyogyszer Es Vegyeszet Process for producing 9-hydroxy-groops-containing 6,7-dihydro-pyrido-square bracket-1,2-a-square bracket closed-pyrimidin derivatives and esters thereof
HU180701B (en) * 1977-12-29 1983-04-29 Chinoin Gyogyszer Es Vegyeszet Process for preparing pyrido-/1,2-a/pyrimidines containing a carboxylic or ester group on the pirimidimering
FR2449689A1 (fr) * 1979-02-20 1980-09-19 Logeais Labor Jacques Nouveaux derives condenses de pyrrolidine ou de piperidine, leur procede de preparation et leurs applications en therapeutique
IL59802A (en) 1979-05-08 1983-07-31 Erba Farmitalia Substituted pyrido(1,2-a)pyrimidine carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them
PL129375B1 (en) * 1980-07-24 1984-05-31 Rhone Poulenc Ind Process for preparing novel derivatives of 2,3,6,7-tetrahydro-thiazole-/3,2-a/-pyrimidin-5-one
HU183408B (en) * 1981-04-28 1984-05-28 Chinoin Gyogyszer Es Vegyeszet Process for producing oral ratard pharmaceutical compositions
CA1211111A (en) * 1982-02-15 1986-09-09 Isao Yanagisawa Process for preparing novel pyrimidone compounds
US5252572A (en) * 1988-02-03 1993-10-12 Chinoin Gyogyszer- Es Vegyeszeti Termekek Gyara Rt. Pyridopyrimidine derivatives, pharmaceutical compositions containing them and process for preparing same
CA2081891C (en) * 1990-05-02 1999-03-16 Daniel T. Chu Quinolizinone type compounds
DE10050662A1 (de) * 2000-10-13 2002-04-18 Gruenenthal Gmbh Substituierte 3,4-Dihydro-pyrido[1,2-a]pyrimidine
DE10050661A1 (de) * 2000-10-13 2002-04-18 Gruenenthal Gmbh Substituierte 3,4-Dihydro-pyrimido[1,2-a]pyrimidine und 3,4-Dihydro-pyrazino[1,2-a]pyrimidine
DE20202183U1 (de) 2002-02-01 2002-06-06 Kretzschmar Michael Baukasten
US7692011B2 (en) * 2002-10-04 2010-04-06 Prana Biotechnology Limited 8-hydroxy and 8-mercapto quinazolinones
CN102225930A (zh) * 2006-04-14 2011-10-26 普拉纳生物技术有限公司 治疗与年龄相关的黄斑变性(amd)的方法
US7955155B2 (en) 2007-07-09 2011-06-07 Mega Brands International Magnetic and electronic toy construction systems and elements
WO2009063901A1 (ja) 2007-11-13 2009-05-22 The University Of Tokyo クオラムセンシング阻害剤
CN103983627A (zh) * 2008-06-17 2014-08-13 韩国巴斯德研究所 作为抗结核病药的吡啶并嘧啶化合物
WO2016086261A1 (en) * 2014-12-02 2016-06-09 Prana Biotechnology Limited 4H-PYRIDO[1,2-a]PYRIMIDIN-4-ONE COMPOUNDS

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH538494A (de) * 1966-11-02 1973-06-30 Chinoin Gyogyszer Es Vegyeszet Verfahren zur Herstellung neuer Homopyrimidazol-Derivate
HU169230B (el) * 1972-03-29 1976-10-28
HU168014B (el) * 1973-03-30 1976-02-28
US4209622A (en) * 1973-03-30 1980-06-24 Chinoin Gygyszer es Vegyeszeti Termekek Gyara Rt. 3-(Ethoxycarbonyl-methyl)-6-methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine
HU168541B (el) * 1973-11-24 1976-05-28
US4022897A (en) * 1974-03-04 1977-05-10 E. R. Squibb & Sons, Inc. CNS active compounds
US3898224A (en) * 1974-09-09 1975-08-05 Squibb & Sons Inc 1,6,7,8-Tetrahydro-4-oxo-4H-pyrido {8 1,2-A{9 pyrimidine-9-carboalkoxy compounds
US3935197A (en) * 1975-05-16 1976-01-27 E. R. Squibb & Sons, Inc. 2-Styryl-4H-pyrido(1,2-a)pyrimidin-4-ones

Also Published As

Publication number Publication date
SE7808770L (sv) 1979-02-20
FR2416892B1 (el) 1983-11-18
JPS5448795A (en) 1979-04-17
US4219649A (en) 1980-08-26
FR2416892A1 (fr) 1979-09-07
YU40985B (en) 1986-10-31
AU518364B2 (en) 1981-09-24
IL55338A0 (en) 1978-10-31
HU178910B (en) 1982-07-28
DD138320A5 (de) 1979-10-24
SU906378A3 (ru) 1982-02-15
NL7808570A (nl) 1979-02-21
CS238901B1 (en) 1985-12-16
GB2006187A (en) 1979-05-02
AT368156B (de) 1982-09-27
DK160045B (da) 1991-01-21
CS541778A1 (en) 1985-05-15
BE869832A (fr) 1978-12-18
US4291036A (en) 1981-09-22
GR64913B (en) 1980-06-09
GB2006187B (en) 1982-10-06
FI66864B (fi) 1984-08-31
SE435383B (sv) 1984-09-24
DE2835004C2 (el) 1989-06-29
CH637541A5 (de) 1983-08-15
DK367478A (da) 1979-02-20
FI782527A (fi) 1979-02-20
IL55338A (en) 1985-10-31
YU196678A (en) 1983-10-31
JPS626554B2 (el) 1987-02-12
AU3900978A (en) 1980-02-21
DE2835004A1 (de) 1979-03-01
ES473181A1 (es) 1979-04-01
CA1152989A (en) 1983-08-30
ATA585278A (de) 1982-01-15
DK160045C (da) 1991-06-10

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Owner name: CHINOIN GYOGUSZER ES VEGYESZETI TERMEKEK