FI66833C - Foerfarande och mellanprodukt foer framstaellning av fenylalkylkarboxylsyraderivat - Google Patents

Foerfarande och mellanprodukt foer framstaellning av fenylalkylkarboxylsyraderivat Download PDF

Info

Publication number
FI66833C
FI66833C FI761833A FI761833A FI66833C FI 66833 C FI66833 C FI 66833C FI 761833 A FI761833 A FI 761833A FI 761833 A FI761833 A FI 761833A FI 66833 C FI66833 C FI 66833C
Authority
FI
Finland
Prior art keywords
mixture
hydrogen
water
added
methyl
Prior art date
Application number
FI761833A
Other languages
English (en)
Finnish (fi)
Other versions
FI761833A (sv
FI66833B (fi
Inventor
Endre Palosi
Georgely Heja
Dezso Korbonits
Csaba Goenczi
Pal Kiss
Rudolf Szebeni
Nee Bako Erzsebet Molnar
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of FI761833A publication Critical patent/FI761833A/fi
Publication of FI66833B publication Critical patent/FI66833B/fi
Application granted granted Critical
Publication of FI66833C publication Critical patent/FI66833C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/84—Unsaturated compounds containing keto groups containing six membered aromatic rings

Claims (4)

1. Förfarande för framställning av fenylalkylkarboxylsyra-derivat med formeln R - CH - COOR1 " väri R är väte eller metyl, R är väte eller metyl, 2 R är väte eller haloqen, och 3 R är fenoxi, bensyl, C1_4-alkyl, fenyl, eller tenoyl och salter därav, kännetecknat av att man omsätter en förening med formeln ____ " Γ~ _ 20 66833 C = C - R 6— 3 R 2 3 väri R, R och R har ovan angivna betydelse, med tallium(III)-nitrat i närvaro av metanol, etylenglykolmetyleter eller di-etyleter vid en temperatur av 5-15°C, och eventuellt omvandlar karbalkoxigruppen genom hydrolys till en karboxylgrupp och eventuellt överför den erhällna produkten i ett salt därav.
2. Förfarande enligt patentkravet 1 för framställning av derivat innehällande fri karboxylsyra, kännetecknat av att man utför reaktionen i dietyleter eller etylenglykolmetyleter i närvaro av vattenhaltig perklorsyra.
3. Förfarande enligt patentkravet 1, kännetecknat av att man utför hydroLysen av karbalkoxigruppen i surt eller alkaliskt medium i närvaro av vatten.
4. Mellanprodukt för framställning av fenylalkylkarboxyl- syraderivat med formeln R - CH - COOR1 —- R2 I R3/ 1 2 väri R är metyl, R är väte eller metyl, R är väte eller halogen och R3 är fenoxi, bensyl, C^_^-alkyl, fenyl eller tenoyl, och salter därav, kännetecknad av att mellanprodukten är ett fenylacetylenderivat med formeln
FI761833A 1975-06-24 1976-06-23 Foerfarande och mellanprodukt foer framstaellning av fenylalkylkarboxylsyraderivat FI66833C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HUCI001595 1975-06-24
HU75CI1595A HU173576B (hu) 1975-06-24 1975-06-24 Sposob poluchenija zamehhjonnykh fenil-alkil-karbonovykh kislot

Publications (3)

Publication Number Publication Date
FI761833A FI761833A (sv) 1976-12-25
FI66833B FI66833B (fi) 1984-08-31
FI66833C true FI66833C (fi) 1984-12-10

Family

ID=10994574

Family Applications (1)

Application Number Title Priority Date Filing Date
FI761833A FI66833C (fi) 1975-06-24 1976-06-23 Foerfarande och mellanprodukt foer framstaellning av fenylalkylkarboxylsyraderivat

Country Status (10)

Country Link
JP (1) JPS5236642A (sv)
CH (1) CH613936A5 (sv)
DK (1) DK281576A (sv)
ES (1) ES449023A1 (sv)
FI (1) FI66833C (sv)
GB (1) GB1552202A (sv)
HU (1) HU173576B (sv)
NL (1) NL7606830A (sv)
SE (1) SE432588B (sv)
SU (1) SU927109A3 (sv)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU39220B (en) * 1976-10-18 1984-08-31 Lek Tovarna Farmacevtskih Process for preparing 2-(3-benzoylphenyl)-propionic acid
JPS5535056A (en) * 1978-09-04 1980-03-11 Hamari Yakuhin Kogyo Kk 3-substituted acetophenone and its preparation
JPS5561132A (en) * 1978-10-31 1980-05-08 Nippon Technical Co Ltd Channel selector of electronic tuning receiver
US4528114A (en) * 1981-12-18 1985-07-09 Hoffmann-La Roche Inc. Acetylenes
DE3802619C1 (sv) * 1988-01-29 1989-09-07 Hoechst Ag, 6230 Frankfurt, De

Also Published As

Publication number Publication date
FI761833A (sv) 1976-12-25
FI66833B (fi) 1984-08-31
GB1552202A (en) 1979-09-12
ES449023A1 (es) 1977-12-01
DK281576A (da) 1976-12-25
JPS5236642A (en) 1977-03-22
SE7607167L (sv) 1976-12-25
NL7606830A (nl) 1976-12-28
SU927109A3 (ru) 1982-05-07
SE432588B (sv) 1984-04-09
HU173576B (hu) 1979-06-28
CH613936A5 (en) 1979-10-31

Similar Documents

Publication Publication Date Title
HU182666B (en) Process for preparing cyclobutanone derivatives
FI66833C (fi) Foerfarande och mellanprodukt foer framstaellning av fenylalkylkarboxylsyraderivat
DK163056B (da) Analogifremgangsmaade til fremstilling af alfa-sulfonyloxyketonacetaler
HU193891B (en) Process for production of new derivatives of 1,2,4-triasole
US4317920A (en) Arylacetic acid derivatives
US4154743A (en) 3-Oxobenzofuranyl-2-idenyl, haloacetic acids
JPH0670064B2 (ja) 二環性イミダゾ−ル誘導体
EP0309626B1 (en) Process for the preparation of dibenzothiepin derivative
JP2719742B2 (ja) フェニルチアゾール誘導体
HU190101B (en) Process for preparing 2,2-dimethyl-3-aryl-cyclopropane-carboxylic acid derivatives
US4393008A (en) 2-Cyano-2-(3-phenoxy-phenyl)-propionic acid amide and preparation thereof
US3442890A (en) Substituted 3-benzazocin-16-ones
US4891433A (en) Process for the preparation of dibenzothiepin derivative
HU198073B (en) Process for producing (+)-3-(3-pyridyl)-1h, 3h-pyrrolo (1,2-c/thiazole-7-carboxylic acid
JPS6284064A (ja) ３−パ−フルオロアルキル−５−ヒドロキシイソオキサゾ−ル類
NO139782B (no) Fremgangsmaate til fremstilling av derivater av 3-benzoylfenyleddiksyre eller 2-(3-benzoylfenyl)-propionsyre
US4385004A (en) Esters of ortho-allylphenol useful for the preparation of arylacetic acid derivatives
US4465855A (en) Process for the preparation of arylacetic acid derivatives
FI62049B (fi) Foerfarande foer framstaellning av indanderivat
JP2549997B2 (ja) 新規ハロケタール化合物
HU182130B (en) Process for preparing 1-aryl-4-methyl-penta-1,3-dienes
JPS584698B2 (ja) ２−（３−ベンゾイルフエニル）プロピオン酸の製造方法
FI66343B (fi) Foerfarande foer framstaellning av alfa-naftylpropionsyraderivat
KR920005417B1 (ko) 디벤조티에핀 유도체의 제조방법
HU193335B (en) Process for preparing halogenated aroyl-acetic ester-derivatives

Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: CHINOIN GYOGUSZER ES VEGYESZETI TERMEKEK