FI65059C - Foerfarande och mellanprodukt foer framstaellning av 3-(3-karboxi-4-hydroxifenyl)-4,5-dihydro-2-fenylbens(e)indol - Google Patents

Foerfarande och mellanprodukt foer framstaellning av 3-(3-karboxi-4-hydroxifenyl)-4,5-dihydro-2-fenylbens(e)indol Download PDF

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Publication number
FI65059C
FI65059C FI771747A FI771747A FI65059C FI 65059 C FI65059 C FI 65059C FI 771747 A FI771747 A FI 771747A FI 771747 A FI771747 A FI 771747A FI 65059 C FI65059 C FI 65059C
Authority
FI
Finland
Prior art keywords
dihydro
carboxy
hydroxyphenyl
dihydronaphthalene
phenacyl
Prior art date
Application number
FI771747A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI65059B (fi
FI771747A (it
Inventor
Richard Charles Effland
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of FI771747A publication Critical patent/FI771747A/fi
Application granted granted Critical
Publication of FI65059B publication Critical patent/FI65059B/fi
Publication of FI65059C publication Critical patent/FI65059C/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/112—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/60—Naphtho [b] pyrroles; Hydrogenated naphtho [b] pyrroles

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
FI771747A 1976-06-03 1977-06-01 Foerfarande och mellanprodukt foer framstaellning av 3-(3-karboxi-4-hydroxifenyl)-4,5-dihydro-2-fenylbens(e)indol FI65059C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69233176 1976-06-03
US05/692,331 US4066659A (en) 1976-06-03 1976-06-03 Method of preparation of 3-(3-carboxy-4-hydroxyphenyl)-4,5-dihydro-2-phenylbenz (e) indole and valuable intermediates related thereto

Publications (3)

Publication Number Publication Date
FI771747A FI771747A (it) 1977-12-04
FI65059B FI65059B (fi) 1983-11-30
FI65059C true FI65059C (fi) 1984-03-12

Family

ID=24780138

Family Applications (1)

Application Number Title Priority Date Filing Date
FI771747A FI65059C (fi) 1976-06-03 1977-06-01 Foerfarande och mellanprodukt foer framstaellning av 3-(3-karboxi-4-hydroxifenyl)-4,5-dihydro-2-fenylbens(e)indol

Country Status (14)

Country Link
US (1) US4066659A (it)
JP (1) JPS5325556A (it)
AT (1) AT353786B (it)
BE (1) BE855406A (it)
CA (1) CA1105936A (it)
CH (1) CH629774A5 (it)
DE (1) DE2724601A1 (it)
DK (1) DK145296C (it)
ES (1) ES459256A1 (it)
FI (1) FI65059C (it)
HU (1) HU176801B (it)
IT (1) IT1076781B (it)
NL (1) NL7705807A (it)
SE (1) SE425391B (it)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1356431A (en) * 1971-06-03 1974-06-12 Wyeth John & Brother Ltd Substituted benz-g-indoles
US3931407A (en) * 1973-03-01 1976-01-06 American Hoechst Corporation Method of treatment with and compositions containing condensed pyrroles bearing an N-phenyl substituent

Also Published As

Publication number Publication date
DE2724601C2 (it) 1988-03-03
CA1105936A (en) 1981-07-28
HU176801B (en) 1981-05-28
DK145296B (da) 1982-10-25
NL7705807A (nl) 1977-12-06
CH629774A5 (de) 1982-05-14
JPS6120546B2 (it) 1986-05-22
BE855406A (fr) 1977-12-05
JPS5325556A (en) 1978-03-09
SE7706526L (sv) 1977-12-04
US4066659A (en) 1978-01-03
SE425391B (sv) 1982-09-27
DE2724601A1 (de) 1977-12-22
FI65059B (fi) 1983-11-30
ATA392877A (de) 1979-05-15
FI771747A (it) 1977-12-04
IT1076781B (it) 1985-04-27
ES459256A1 (es) 1978-03-01
DK243677A (da) 1977-12-04
DK145296C (da) 1983-03-14
AT353786B (de) 1979-12-10

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Legal Events

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MM Patent lapsed

Owner name: HOECHST AKTIENGESELLSCHAFT