JPS5325556A - Preparation of 33*33carboxyy44hydroxyphenyl** 4*55dihydoo22phenylbenz*e*indole - Google Patents

Preparation of 33*33carboxyy44hydroxyphenyl** 4*55dihydoo22phenylbenz*e*indole

Info

Publication number
JPS5325556A
JPS5325556A JP6568277A JP6568277A JPS5325556A JP S5325556 A JPS5325556 A JP S5325556A JP 6568277 A JP6568277 A JP 6568277A JP 6568277 A JP6568277 A JP 6568277A JP S5325556 A JPS5325556 A JP S5325556A
Authority
JP
Japan
Prior art keywords
indole
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP6568277A
Other languages
English (en)
Other versions
JPS6120546B2 (ja
Inventor
Chiyaaruzu Efurando Richiyaado
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of JPS5325556A publication Critical patent/JPS5325556A/ja
Publication of JPS6120546B2 publication Critical patent/JPS6120546B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/112—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/60—Naphtho [b] pyrroles; Hydrogenated naphtho [b] pyrroles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP6568277A 1976-06-03 1977-06-03 Preparation of 33*33carboxyy44hydroxyphenyl** 4*55dihydoo22phenylbenz*e*indole Granted JPS5325556A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/692,331 US4066659A (en) 1976-06-03 1976-06-03 Method of preparation of 3-(3-carboxy-4-hydroxyphenyl)-4,5-dihydro-2-phenylbenz (e) indole and valuable intermediates related thereto

Publications (2)

Publication Number Publication Date
JPS5325556A true JPS5325556A (en) 1978-03-09
JPS6120546B2 JPS6120546B2 (ja) 1986-05-22

Family

ID=24780138

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6568277A Granted JPS5325556A (en) 1976-06-03 1977-06-03 Preparation of 33*33carboxyy44hydroxyphenyl** 4*55dihydoo22phenylbenz*e*indole

Country Status (14)

Country Link
US (1) US4066659A (ja)
JP (1) JPS5325556A (ja)
AT (1) AT353786B (ja)
BE (1) BE855406A (ja)
CA (1) CA1105936A (ja)
CH (1) CH629774A5 (ja)
DE (1) DE2724601A1 (ja)
DK (1) DK145296C (ja)
ES (1) ES459256A1 (ja)
FI (1) FI65059C (ja)
HU (1) HU176801B (ja)
IT (1) IT1076781B (ja)
NL (1) NL7705807A (ja)
SE (1) SE425391B (ja)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1356431A (en) * 1971-06-03 1974-06-12 Wyeth John & Brother Ltd Substituted benz-g-indoles
US3931407A (en) * 1973-03-01 1976-01-06 American Hoechst Corporation Method of treatment with and compositions containing condensed pyrroles bearing an N-phenyl substituent

Also Published As

Publication number Publication date
DK145296C (da) 1983-03-14
ATA392877A (de) 1979-05-15
HU176801B (en) 1981-05-28
BE855406A (fr) 1977-12-05
FI771747A (ja) 1977-12-04
CH629774A5 (de) 1982-05-14
CA1105936A (en) 1981-07-28
SE7706526L (sv) 1977-12-04
AT353786B (de) 1979-12-10
NL7705807A (nl) 1977-12-06
DK145296B (da) 1982-10-25
DE2724601A1 (de) 1977-12-22
FI65059B (fi) 1983-11-30
US4066659A (en) 1978-01-03
IT1076781B (it) 1985-04-27
SE425391B (sv) 1982-09-27
ES459256A1 (es) 1978-03-01
DK243677A (da) 1977-12-04
FI65059C (fi) 1984-03-12
DE2724601C2 (ja) 1988-03-03
JPS6120546B2 (ja) 1986-05-22

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