DK145296C - Fremgangsmaade til fremstilling af 3-(3-carboxy-4-hydroxyphenyl)-4,5-dihydro-2-phenylbenz(e)indol - Google Patents

Fremgangsmaade til fremstilling af 3-(3-carboxy-4-hydroxyphenyl)-4,5-dihydro-2-phenylbenz(e)indol

Info

Publication number
DK145296C
DK145296C DK243677A DK243677A DK145296C DK 145296 C DK145296 C DK 145296C DK 243677 A DK243677 A DK 243677A DK 243677 A DK243677 A DK 243677A DK 145296 C DK145296 C DK 145296C
Authority
DK
Denmark
Prior art keywords
phenylbenze
indol
hydroxyphenyl
dihydro
carboxy
Prior art date
Application number
DK243677A
Other languages
English (en)
Other versions
DK145296B (da
DK243677A (da
Inventor
R C Effland
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of DK243677A publication Critical patent/DK243677A/da
Publication of DK145296B publication Critical patent/DK145296B/da
Application granted granted Critical
Publication of DK145296C publication Critical patent/DK145296C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/112—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/60—Naphtho [b] pyrroles; Hydrogenated naphtho [b] pyrroles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK243677A 1976-06-03 1977-06-02 Fremgangsmaade til fremstilling af 3-(3-carboxy-4-hydroxyphenyl)-4,5-dihydro-2-phenylbenz(e)indol DK145296C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69233176 1976-06-03
US05/692,331 US4066659A (en) 1976-06-03 1976-06-03 Method of preparation of 3-(3-carboxy-4-hydroxyphenyl)-4,5-dihydro-2-phenylbenz (e) indole and valuable intermediates related thereto

Publications (3)

Publication Number Publication Date
DK243677A DK243677A (da) 1977-12-04
DK145296B DK145296B (da) 1982-10-25
DK145296C true DK145296C (da) 1983-03-14

Family

ID=24780138

Family Applications (1)

Application Number Title Priority Date Filing Date
DK243677A DK145296C (da) 1976-06-03 1977-06-02 Fremgangsmaade til fremstilling af 3-(3-carboxy-4-hydroxyphenyl)-4,5-dihydro-2-phenylbenz(e)indol

Country Status (14)

Country Link
US (1) US4066659A (da)
JP (1) JPS5325556A (da)
AT (1) AT353786B (da)
BE (1) BE855406A (da)
CA (1) CA1105936A (da)
CH (1) CH629774A5 (da)
DE (1) DE2724601A1 (da)
DK (1) DK145296C (da)
ES (1) ES459256A1 (da)
FI (1) FI65059C (da)
HU (1) HU176801B (da)
IT (1) IT1076781B (da)
NL (1) NL7705807A (da)
SE (1) SE425391B (da)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1356431A (en) * 1971-06-03 1974-06-12 Wyeth John & Brother Ltd Substituted benz-g-indoles
US3931407A (en) * 1973-03-01 1976-01-06 American Hoechst Corporation Method of treatment with and compositions containing condensed pyrroles bearing an N-phenyl substituent

Also Published As

Publication number Publication date
ATA392877A (de) 1979-05-15
HU176801B (en) 1981-05-28
BE855406A (fr) 1977-12-05
FI771747A (da) 1977-12-04
CH629774A5 (de) 1982-05-14
CA1105936A (en) 1981-07-28
SE7706526L (sv) 1977-12-04
AT353786B (de) 1979-12-10
NL7705807A (nl) 1977-12-06
DK145296B (da) 1982-10-25
DE2724601A1 (de) 1977-12-22
FI65059B (fi) 1983-11-30
JPS5325556A (en) 1978-03-09
US4066659A (en) 1978-01-03
IT1076781B (it) 1985-04-27
SE425391B (sv) 1982-09-27
ES459256A1 (es) 1978-03-01
DK243677A (da) 1977-12-04
FI65059C (fi) 1984-03-12
DE2724601C2 (da) 1988-03-03
JPS6120546B2 (da) 1986-05-22

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