FI64165C - Nytt foerfarande foer framstaellning av s-trietylfosfinguld-2,3,4,6-tetra-0-acetyl-1-tio-beta-d-glukopyranosid (auranofin) - Google Patents

Nytt foerfarande foer framstaellning av s-trietylfosfinguld-2,3,4,6-tetra-0-acetyl-1-tio-beta-d-glukopyranosid (auranofin) Download PDF

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Publication number
FI64165C
FI64165C FI781155A FI781155A FI64165C FI 64165 C FI64165 C FI 64165C FI 781155 A FI781155 A FI 781155A FI 781155 A FI781155 A FI 781155A FI 64165 C FI64165 C FI 64165C
Authority
FI
Finland
Prior art keywords
auranofin
acetyl
tetra
oac
thio
Prior art date
Application number
FI781155A
Other languages
English (en)
Finnish (fi)
Other versions
FI64165B (fi
FI781155A (fi
Inventor
David Taylor Hill
Blaine Mote Sutton
Ivan Lantos
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of FI781155A publication Critical patent/FI781155A/fi
Publication of FI64165B publication Critical patent/FI64165B/fi
Application granted granted Critical
Publication of FI64165C publication Critical patent/FI64165C/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Steroid Compounds (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Glass Compositions (AREA)
  • Cosmetics (AREA)
FI781155A 1977-04-21 1978-04-17 Nytt foerfarande foer framstaellning av s-trietylfosfinguld-2,3,4,6-tetra-0-acetyl-1-tio-beta-d-glukopyranosid (auranofin) FI64165C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/789,603 US4131732A (en) 1977-04-21 1977-04-21 Method for preparing auranofin
US78960377 1977-04-21

Publications (3)

Publication Number Publication Date
FI781155A FI781155A (fi) 1978-10-22
FI64165B FI64165B (fi) 1983-06-30
FI64165C true FI64165C (fi) 1983-10-10

Family

ID=25148131

Family Applications (1)

Application Number Title Priority Date Filing Date
FI781155A FI64165C (fi) 1977-04-21 1978-04-17 Nytt foerfarande foer framstaellning av s-trietylfosfinguld-2,3,4,6-tetra-0-acetyl-1-tio-beta-d-glukopyranosid (auranofin)

Country Status (20)

Country Link
US (1) US4131732A (fr)
AR (1) AR215695A1 (fr)
AT (1) AT361507B (fr)
BG (1) BG28716A3 (fr)
CH (1) CH633561A5 (fr)
CS (1) CS194843B2 (fr)
DD (1) DD136745A5 (fr)
DK (1) DK150858C (fr)
ES (1) ES468938A1 (fr)
FI (1) FI64165C (fr)
FR (1) FR2387996A1 (fr)
IE (1) IE47046B1 (fr)
IL (1) IL54528A0 (fr)
IT (1) IT1094084B (fr)
NO (1) NO146328C (fr)
PL (1) PL111162B1 (fr)
PT (1) PT67904B (fr)
SE (1) SE444568B (fr)
SU (1) SU795486A3 (fr)
YU (1) YU39417B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4301152A (en) * 1979-10-26 1981-11-17 Merck & Co., Inc. Immunologic adjuvant
NZ228367A (en) * 1988-03-23 1992-02-25 Smithkline Beecham Corp Topical composition containing a gold compound for treating inflammatory conditions
US5527779A (en) * 1988-03-23 1996-06-18 Top Gold Pty Limited Topically applied gold organic complex
CN1057092C (zh) * 1997-10-31 2000-10-04 昆明贵金属研究所 金诺芬的制备方法
US9173898B2 (en) * 2010-10-12 2015-11-03 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods of treating giardiasis
WO2016124936A1 (fr) 2015-02-06 2016-08-11 Auspherix Limited Inhibition de cellules sessiles microbiennes
WO2016124935A1 (fr) 2015-02-06 2016-08-11 Auspherix Limited Procédés d'inhibition et de dispersion de biofilms à l'aide d'auranofine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE757672A (fr) * 1969-10-28 1971-04-19 Smith Kline French Lab Complexes d'auro-trialcoylphosphine de 1-beta-D-glucopyranosides
DK129847B (da) * 1969-10-28 1974-11-25 Smith Kline French Lab Analogifremgangsmåde til fremstilling af trialkylphosphinguldkomplekser af 1-β-D-glucopyranosider.
DK135897B (da) * 1969-10-28 1977-07-11 Smith Kline French Lab Fremgangsmåde til fremstilling af trialkylphosphinguldhalogenider.

Also Published As

Publication number Publication date
SE7804208L (sv) 1978-10-22
FR2387996A1 (fr) 1978-11-17
ATA274678A (de) 1980-08-15
DK150858B (da) 1987-07-06
YU39417B (en) 1984-12-31
IT7822402A0 (it) 1978-04-17
FI64165B (fi) 1983-06-30
AR215695A1 (es) 1979-10-31
US4131732A (en) 1978-12-26
AT361507B (de) 1981-03-10
DD136745A5 (de) 1979-07-25
YU95478A (en) 1982-10-31
PL206281A1 (pl) 1979-03-12
PL111162B1 (en) 1980-08-30
BG28716A3 (en) 1980-06-16
SU795486A3 (ru) 1981-01-07
CS194843B2 (en) 1979-12-31
IT1094084B (it) 1985-07-26
DK150858C (da) 1987-12-07
IL54528A0 (en) 1978-07-31
IE47046B1 (en) 1983-12-14
PT67904B (en) 1979-10-15
NO146328B (no) 1982-06-01
FI781155A (fi) 1978-10-22
SE444568B (sv) 1986-04-21
NO781391L (no) 1978-10-24
IE780753L (en) 1978-10-21
FR2387996B1 (fr) 1980-08-01
PT67904A (en) 1978-05-01
ES468938A1 (es) 1978-12-16
NO146328C (no) 1982-09-08
DK163978A (da) 1978-10-22
CH633561A5 (de) 1982-12-15

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Owner name: SMITHKLINE BECKMAN CORPORATION