FI62832C - Foerfarande foer framstaellning av 1,2,3,4-tetrahydroisokinoliner - Google Patents

Foerfarande foer framstaellning av 1,2,3,4-tetrahydroisokinoliner Download PDF

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Publication number
FI62832C
FI62832C FI760230A FI760230A FI62832C FI 62832 C FI62832 C FI 62832C FI 760230 A FI760230 A FI 760230A FI 760230 A FI760230 A FI 760230A FI 62832 C FI62832 C FI 62832C
Authority
FI
Finland
Prior art keywords
chloroacetyl
formula
methyl
cyclohexylcarboxamidomethyl
compound
Prior art date
Application number
FI760230A
Other languages
English (en)
Finnish (fi)
Other versions
FI62832B (fi
FI760230A (ja
Inventor
Juergen Seubert
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of FI760230A publication Critical patent/FI760230A/fi
Publication of FI62832B publication Critical patent/FI62832B/fi
Application granted granted Critical
Publication of FI62832C publication Critical patent/FI62832C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
FI760230A 1975-02-01 1976-01-30 Foerfarande foer framstaellning av 1,2,3,4-tetrahydroisokinoliner FI62832C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19752504250 DE2504250A1 (de) 1975-02-01 1975-02-01 Tetrahydroisochinolin-derivate und verfahren zu ihrer herstellung
DE2504250 1975-02-01

Publications (3)

Publication Number Publication Date
FI760230A FI760230A (ja) 1976-08-02
FI62832B FI62832B (fi) 1982-11-30
FI62832C true FI62832C (fi) 1983-03-10

Family

ID=5937889

Family Applications (1)

Application Number Title Priority Date Filing Date
FI760230A FI62832C (fi) 1975-02-01 1976-01-30 Foerfarande foer framstaellning av 1,2,3,4-tetrahydroisokinoliner

Country Status (19)

Country Link
US (1) US4362875A (ja)
JP (1) JPS6113472B2 (ja)
AT (1) AT361927B (ja)
BE (1) BE838079A (ja)
CA (1) CA1085401A (ja)
CH (1) CH620680A5 (ja)
CS (1) CS188267B2 (ja)
DE (1) DE2504250A1 (ja)
DK (1) DK37376A (ja)
ES (1) ES444804A1 (ja)
FI (1) FI62832C (ja)
FR (1) FR2299032A1 (ja)
GB (1) GB1511463A (ja)
HU (1) HU171491B (ja)
IE (1) IE42945B1 (ja)
LU (1) LU74272A1 (ja)
NL (1) NL7600985A (ja)
SE (1) SE433745B (ja)
YU (1) YU24176A (ja)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2520740A1 (fr) * 1982-01-29 1983-08-05 Sanofi Sa Procede pour la preparation d'acyl-2-hexahydro-1,3,4,6,7,11b-2h-pyrazino (2,1-a) isoquinoleinones-4 et intermediaires
GB8531615D0 (en) * 1985-12-23 1986-02-05 Zambeletti Spa L Compounds
JPH055652Y2 (ja) * 1987-12-26 1993-02-15
JPH01103171U (ja) * 1987-12-26 1989-07-12
ATE97893T1 (de) * 1988-02-19 1993-12-15 Smithkline Beecham Farma 1,2,3,4-tetrahydroisoquinoline, verfharen zu ihrer herstellung und ihre verwendung als kappa- rezeptor agonisten.
US5389638A (en) * 1993-09-10 1995-02-14 Abbott Laboratories Tetrahydroisoquinolines as alpha-2 antagonists and biogenic amine uptake inhibitors
CN100503582C (zh) * 2005-03-01 2009-06-24 江苏工业学院 吡喹酮合成工艺
EP2408771B1 (en) 2009-03-17 2016-11-16 Concert Pharmaceuticals, Inc. Pyrazinoisoquinoline compounds
CN102093346B (zh) * 2010-03-16 2012-09-05 浙江金伯士药业有限公司 一种吡喹酮的制备方法
WO2013067036A1 (en) 2011-10-31 2013-05-10 Rutgers, The State University Of New Jersey Direct inhibitors of keap1-nrf2 interaction as antioxidant inflammation modulators
CN103160562B (zh) * 2013-02-28 2014-04-23 苏州同力生物医药有限公司 一种合成左旋吡喹酮的方法
JP6359208B2 (ja) * 2015-02-12 2018-07-18 浙江▲海▼正▲薬▼▲業▼股▲フン▼有限公司 プラジカンテル及びその中間体化合物の製造方法
AU2016316436B2 (en) * 2015-09-01 2021-04-29 Merck Patent Gmbh Method for the production of praziquantel and precursors thereof
WO2018063472A1 (en) 2016-09-27 2018-04-05 Reyoung Corporation Compositions for treating parasitic diseases and methods thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2361390A1 (de) * 1973-12-10 1975-06-19 Merck Patent Gmbh Isochinolinderivate und verfahren zu ihrer herstellung
US4118494A (en) * 1974-08-14 1978-10-03 Hoechst Aktiengesellschaft Substituted 3,4-dihydro-2H-isoquinolin-1-thiones

Also Published As

Publication number Publication date
CS188267B2 (en) 1979-02-28
LU74272A1 (ja) 1977-08-03
FR2299032B1 (ja) 1981-12-31
ES444804A1 (es) 1977-12-01
IE42945L (en) 1976-08-01
FI62832B (fi) 1982-11-30
YU24176A (en) 1982-05-31
FR2299032A1 (fr) 1976-08-27
JPS51101986A (ja) 1976-09-08
SE7600954L (sv) 1976-08-02
CH620680A5 (ja) 1980-12-15
ATA66576A (de) 1980-09-15
IE42945B1 (en) 1980-11-19
DE2504250A1 (de) 1976-08-05
SE433745B (sv) 1984-06-12
FI760230A (ja) 1976-08-02
JPS6113472B2 (ja) 1986-04-14
CA1085401A (en) 1980-09-09
DK37376A (da) 1976-08-02
US4362875A (en) 1982-12-07
AT361927B (de) 1981-04-10
GB1511463A (en) 1978-05-17
NL7600985A (nl) 1976-08-03
HU171491B (hu) 1978-01-28
BE838079A (fr) 1976-07-30

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Owner name: MERCK PATENT GMBH