JPS51101986A - - Google Patents

Info

Publication number
JPS51101986A
JPS51101986A JP51010781A JP1078176A JPS51101986A JP S51101986 A JPS51101986 A JP S51101986A JP 51010781 A JP51010781 A JP 51010781A JP 1078176 A JP1078176 A JP 1078176A JP S51101986 A JPS51101986 A JP S51101986A
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP51010781A
Other versions
JPS6113472B2 (ja
Inventor
Zoiberuto Yurugen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Publication of JPS51101986A publication Critical patent/JPS51101986A/ja
Publication of JPS6113472B2 publication Critical patent/JPS6113472B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP51010781A 1975-02-01 1976-02-02 Expired JPS6113472B2 (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19752504250 DE2504250A1 (de) 1975-02-01 1975-02-01 Tetrahydroisochinolin-derivate und verfahren zu ihrer herstellung

Publications (2)

Publication Number Publication Date
JPS51101986A true JPS51101986A (ja) 1976-09-08
JPS6113472B2 JPS6113472B2 (ja) 1986-04-14

Family

ID=5937889

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51010781A Expired JPS6113472B2 (ja) 1975-02-01 1976-02-02

Country Status (19)

Country Link
US (1) US4362875A (ja)
JP (1) JPS6113472B2 (ja)
AT (1) AT361927B (ja)
BE (1) BE838079A (ja)
CA (1) CA1085401A (ja)
CH (1) CH620680A5 (ja)
CS (1) CS188267B2 (ja)
DE (1) DE2504250A1 (ja)
DK (1) DK37376A (ja)
ES (1) ES444804A1 (ja)
FI (1) FI62832C (ja)
FR (1) FR2299032A1 (ja)
GB (1) GB1511463A (ja)
HU (1) HU171491B (ja)
IE (1) IE42945B1 (ja)
LU (1) LU74272A1 (ja)
NL (1) NL7600985A (ja)
SE (1) SE433745B (ja)
YU (1) YU24176A (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0219379A (ja) * 1988-02-19 1990-01-23 Dottore Lo Zambeletti Spa 新規化合物、その製法及びそれを含む医薬組成物

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2520740A1 (fr) * 1982-01-29 1983-08-05 Sanofi Sa Procede pour la preparation d'acyl-2-hexahydro-1,3,4,6,7,11b-2h-pyrazino (2,1-a) isoquinoleinones-4 et intermediaires
GB8531615D0 (en) * 1985-12-23 1986-02-05 Zambeletti Spa L Compounds
JPH01103171U (ja) * 1987-12-26 1989-07-12
JPH055652Y2 (ja) * 1987-12-26 1993-02-15
US5389638A (en) * 1993-09-10 1995-02-14 Abbott Laboratories Tetrahydroisoquinolines as alpha-2 antagonists and biogenic amine uptake inhibitors
CN100503582C (zh) * 2005-03-01 2009-06-24 江苏工业学院 吡喹酮合成工艺
AP2909A (en) 2009-03-17 2014-05-31 Concert Pharmaceuticals Inc Pyrazinoisoquinoline Compounds
CN102093346B (zh) * 2010-03-16 2012-09-05 浙江金伯士药业有限公司 一种吡喹酮的制备方法
US20140256767A1 (en) 2011-10-31 2014-09-11 The Broad Institute, Inc. Direct inhibitors of keap1-nrf2 interaction as antioxidant inflammation modulators
CN103160562B (zh) * 2013-02-28 2014-04-23 苏州同力生物医药有限公司 一种合成左旋吡喹酮的方法
WO2016127350A1 (zh) 2015-02-12 2016-08-18 浙江海正药业股份有限公司 一种吡喹酮的制备方法及其中间体化合物
CA2996813C (en) * 2015-09-01 2023-09-26 Merck Patent Gmbh Method for the production of praziquantel and precursors thereof
WO2018063472A1 (en) 2016-09-27 2018-04-05 Reyoung Corporation Compositions for treating parasitic diseases and methods thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2361390A1 (de) * 1973-12-10 1975-06-19 Merck Patent Gmbh Isochinolinderivate und verfahren zu ihrer herstellung
US4118494A (en) * 1974-08-14 1978-10-03 Hoechst Aktiengesellschaft Substituted 3,4-dihydro-2H-isoquinolin-1-thiones

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0219379A (ja) * 1988-02-19 1990-01-23 Dottore Lo Zambeletti Spa 新規化合物、その製法及びそれを含む医薬組成物

Also Published As

Publication number Publication date
NL7600985A (nl) 1976-08-03
IE42945B1 (en) 1980-11-19
YU24176A (en) 1982-05-31
US4362875A (en) 1982-12-07
BE838079A (fr) 1976-07-30
CH620680A5 (ja) 1980-12-15
CS188267B2 (en) 1979-02-28
CA1085401A (en) 1980-09-09
JPS6113472B2 (ja) 1986-04-14
SE7600954L (sv) 1976-08-02
FR2299032B1 (ja) 1981-12-31
ATA66576A (de) 1980-09-15
IE42945L (en) 1976-08-01
DE2504250A1 (de) 1976-08-05
AT361927B (de) 1981-04-10
LU74272A1 (ja) 1977-08-03
HU171491B (hu) 1978-01-28
ES444804A1 (es) 1977-12-01
GB1511463A (en) 1978-05-17
FI62832B (fi) 1982-11-30
FI62832C (fi) 1983-03-10
SE433745B (sv) 1984-06-12
FI760230A (ja) 1976-08-02
FR2299032A1 (fr) 1976-08-27
DK37376A (da) 1976-08-02

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