CS188267B2 - Method of producing derivatives of tetrahydroisoquinoline - Google Patents

Method of producing derivatives of tetrahydroisoquinoline

Info

Publication number
CS188267B2
CS188267B2 CS76577A CS57776A CS188267B2 CS 188267 B2 CS188267 B2 CS 188267B2 CS 76577 A CS76577 A CS 76577A CS 57776 A CS57776 A CS 57776A CS 188267 B2 CS188267 B2 CS 188267B2
Authority
CS
Czechoslovakia
Prior art keywords
tetrahydroisoquinoline
producing derivatives
derivatives
producing
Prior art date
Application number
CS76577A
Other languages
Czech (cs)
English (en)
Inventor
Juergen Seubert
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of CS188267B2 publication Critical patent/CS188267B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CS76577A 1975-02-01 1976-01-29 Method of producing derivatives of tetrahydroisoquinoline CS188267B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19752504250 DE2504250A1 (de) 1975-02-01 1975-02-01 Tetrahydroisochinolin-derivate und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
CS188267B2 true CS188267B2 (en) 1979-02-28

Family

ID=5937889

Family Applications (1)

Application Number Title Priority Date Filing Date
CS76577A CS188267B2 (en) 1975-02-01 1976-01-29 Method of producing derivatives of tetrahydroisoquinoline

Country Status (19)

Country Link
US (1) US4362875A (ja)
JP (1) JPS6113472B2 (ja)
AT (1) AT361927B (ja)
BE (1) BE838079A (ja)
CA (1) CA1085401A (ja)
CH (1) CH620680A5 (ja)
CS (1) CS188267B2 (ja)
DE (1) DE2504250A1 (ja)
DK (1) DK37376A (ja)
ES (1) ES444804A1 (ja)
FI (1) FI62832C (ja)
FR (1) FR2299032A1 (ja)
GB (1) GB1511463A (ja)
HU (1) HU171491B (ja)
IE (1) IE42945B1 (ja)
LU (1) LU74272A1 (ja)
NL (1) NL7600985A (ja)
SE (1) SE433745B (ja)
YU (1) YU24176A (ja)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2520740A1 (fr) * 1982-01-29 1983-08-05 Sanofi Sa Procede pour la preparation d'acyl-2-hexahydro-1,3,4,6,7,11b-2h-pyrazino (2,1-a) isoquinoleinones-4 et intermediaires
GB8531615D0 (en) * 1985-12-23 1986-02-05 Zambeletti Spa L Compounds
JPH01103171U (ja) * 1987-12-26 1989-07-12
JPH055652Y2 (ja) * 1987-12-26 1993-02-15
DE68910999T2 (de) * 1988-02-19 1994-03-24 Smithkline Beecham Farma 1,2,3,4-Tetrahydroisoquinoline, Verfharen zu ihrer Herstellung und ihre Verwendung als Kappa-Rezeptor Agonisten.
US5389638A (en) * 1993-09-10 1995-02-14 Abbott Laboratories Tetrahydroisoquinolines as alpha-2 antagonists and biogenic amine uptake inhibitors
CN100503582C (zh) * 2005-03-01 2009-06-24 江苏工业学院 吡喹酮合成工艺
US8563554B2 (en) 2009-03-17 2013-10-22 Concert Pharmaceuticals, Inc. Deuterated pyrazinoisoquinoline compounds
CN102093346B (zh) * 2010-03-16 2012-09-05 浙江金伯士药业有限公司 一种吡喹酮的制备方法
WO2013067036A1 (en) * 2011-10-31 2013-05-10 Rutgers, The State University Of New Jersey Direct inhibitors of keap1-nrf2 interaction as antioxidant inflammation modulators
CN103160562B (zh) * 2013-02-28 2014-04-23 苏州同力生物医药有限公司 一种合成左旋吡喹酮的方法
EP3257852B1 (en) 2015-02-12 2020-01-01 Zhejiang Hisun Pharmaceutical Co., Ltd. Preparation method for praziquantel and intermediate compounds thereof
EP3344605B1 (en) * 2015-09-01 2020-05-13 Merck Patent GmbH Method for the production of praziquantel and precursors thereof
CN110035763B (zh) 2016-09-27 2022-11-15 瑞阳公司 用于治疗寄生虫病的组合物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2361390A1 (de) * 1973-12-10 1975-06-19 Merck Patent Gmbh Isochinolinderivate und verfahren zu ihrer herstellung
US4118494A (en) * 1974-08-14 1978-10-03 Hoechst Aktiengesellschaft Substituted 3,4-dihydro-2H-isoquinolin-1-thiones

Also Published As

Publication number Publication date
JPS51101986A (ja) 1976-09-08
IE42945B1 (en) 1980-11-19
HU171491B (hu) 1978-01-28
ATA66576A (de) 1980-09-15
YU24176A (en) 1982-05-31
DE2504250A1 (de) 1976-08-05
NL7600985A (nl) 1976-08-03
CH620680A5 (ja) 1980-12-15
FR2299032A1 (fr) 1976-08-27
FI62832C (fi) 1983-03-10
IE42945L (en) 1976-08-01
ES444804A1 (es) 1977-12-01
BE838079A (fr) 1976-07-30
SE433745B (sv) 1984-06-12
LU74272A1 (ja) 1977-08-03
DK37376A (da) 1976-08-02
SE7600954L (sv) 1976-08-02
US4362875A (en) 1982-12-07
JPS6113472B2 (ja) 1986-04-14
FR2299032B1 (ja) 1981-12-31
CA1085401A (en) 1980-09-09
AT361927B (de) 1981-04-10
FI760230A (ja) 1976-08-02
GB1511463A (en) 1978-05-17
FI62832B (fi) 1982-11-30

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