FI61690C - Foerfarande foer framstaellning av 5-fluor-2-metyl-1-(p-metylsulfinylbensyliden)-indenyl-3-aettiksyra - Google Patents

Foerfarande foer framstaellning av 5-fluor-2-metyl-1-(p-metylsulfinylbensyliden)-indenyl-3-aettiksyra Download PDF

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Publication number
FI61690C
FI61690C FI752573A FI752573A FI61690C FI 61690 C FI61690 C FI 61690C FI 752573 A FI752573 A FI 752573A FI 752573 A FI752573 A FI 752573A FI 61690 C FI61690 C FI 61690C
Authority
FI
Finland
Prior art keywords
acetic acid
methyl
para
fluoro
indene
Prior art date
Application number
FI752573A
Other languages
English (en)
Finnish (fi)
Other versions
FI752573A (xx
FI61690B (fi
Inventor
Roger James Tull
David Gregory Melillo
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of FI752573A publication Critical patent/FI752573A/fi
Priority to FI802853A priority Critical patent/FI802853A/fi
Application granted granted Critical
Publication of FI61690B publication Critical patent/FI61690B/fi
Publication of FI61690C publication Critical patent/FI61690C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/62—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings and other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/56—Unsaturated compounds containing hydroxy or O-metal groups containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/88—Unsaturated compounds containing keto groups containing halogen
FI752573A 1974-10-02 1975-09-15 Foerfarande foer framstaellning av 5-fluor-2-metyl-1-(p-metylsulfinylbensyliden)-indenyl-3-aettiksyra FI61690C (fi)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI802853A FI802853A (fi) 1974-10-02 1980-09-11 Foerfarande foer framstaellning av 5-fluor-2-metyl-indanol-3-aettikssyra

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51134974 1974-10-02
US05/511,349 US3998875A (en) 1974-10-02 1974-10-02 Process of preparing 5-fluoro-2-methyl-1-(paramethylsulfinylbenzylidene)-indenyl-3-acetic acid

Publications (3)

Publication Number Publication Date
FI752573A FI752573A (xx) 1976-04-03
FI61690B FI61690B (fi) 1982-05-31
FI61690C true FI61690C (fi) 1982-09-10

Family

ID=24034513

Family Applications (1)

Application Number Title Priority Date Filing Date
FI752573A FI61690C (fi) 1974-10-02 1975-09-15 Foerfarande foer framstaellning av 5-fluor-2-metyl-1-(p-metylsulfinylbensyliden)-indenyl-3-aettiksyra

Country Status (21)

Country Link
US (2) US3998875A (xx)
JP (1) JPS51105049A (xx)
AT (1) AT344154B (xx)
BE (1) BE834080A (xx)
CH (1) CH615158A5 (xx)
CS (2) CS183850B2 (xx)
DD (1) DD125639A5 (xx)
DE (1) DE2543870A1 (xx)
DK (1) DK416975A (xx)
ES (1) ES441404A1 (xx)
FI (1) FI61690C (xx)
FR (1) FR2286817A1 (xx)
GB (1) GB1483980A (xx)
HU (1) HU171805B (xx)
LU (1) LU73496A1 (xx)
NL (1) NL7510944A (xx)
NO (2) NO141050C (xx)
PL (2) PL103093B1 (xx)
SE (1) SE7510329L (xx)
SU (3) SU860695A1 (xx)
YU (2) YU239875A (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4368127A (en) * 1979-07-02 1983-01-11 Akzona Incorporated Fabric softening compounds and method
EP0071006B1 (en) * 1981-06-11 1985-09-18 Sumitomo Chemical Company, Limited Tetrahydronaphthalene derivatives and their production
IT1190371B (it) * 1985-06-19 1988-02-16 Zambon Spa Processo per la preparazione dell'acido cis-5-fluoro-2-metil-1-(4-metiltiobenziliden)-indenil-3-acetico
US6121321A (en) * 1996-06-13 2000-09-19 Cell Pathways, Inc. Substituted methoxy benzylidene indenyl acetic and propionic acids for treating patients with precancerous lesions
US6063818A (en) * 1996-06-13 2000-05-16 Cell Pathways Inc. Substituted benzylidene indenyl formamides, acetamides and propionamides
US5965619A (en) * 1996-06-13 1999-10-12 Cell Pathways Inc. Method for treating patients having precancerous lesions with substituted indene derivatives
US5998477A (en) * 1996-06-13 1999-12-07 Cell Pathways Inc. Substituted methoxy benzylidene indenyl-acetic and propionic acids for treating patients with precancerous lesions
CA2261193C (en) * 1996-07-01 2005-01-11 The Procter & Gamble Company Dehydrated potato flakes
US5948779A (en) * 1997-12-12 1999-09-07 Cell Pathways, Inc. Substituted condensation products of n-benzyl-3-indenyl acetamides with heterocyclic aldehydes
US6028116A (en) * 1998-04-03 2000-02-22 Cell Pathways, Inc. Substituted condensation products of 1H-indenyl-hydroxyalkanes with aldehydes for neoplasia

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3532752A (en) * 1965-12-30 1970-10-06 Merck & Co Inc 1-alkylidene-3-indenyl aliphatic amines
US3547923A (en) * 1968-03-25 1970-12-15 Bristol Myers Co Piperazyl ethyl 7h-benzocycloheptenes
US3692825A (en) * 1970-05-01 1972-09-19 Merck & Co Inc Indanyl acetic acids
US3654349A (en) * 1970-05-01 1972-04-04 Merck & Co Inc Substituted indenyl acetic acids
US3725548A (en) * 1970-05-01 1973-04-03 Merck & Co Inc Substituted indenyl acetic acids in the treatment of pain, fever or inflammation
US3766259A (en) * 1970-05-01 1973-10-16 Merck & Co Inc Preparation of 1-aryl-3-indenyl acetic acids
US3870753A (en) * 1973-12-20 1975-03-11 Merck & Co Inc Process for preparing indenyl acetic acids

Also Published As

Publication number Publication date
FR2286817B1 (xx) 1979-01-05
DE2543870A1 (de) 1976-04-22
HU171805B (hu) 1978-03-28
GB1483980A (en) 1977-08-24
NO146198B (no) 1982-05-10
ATA734575A (de) 1977-11-15
NO791267L (no) 1976-04-05
US4123457A (en) 1978-10-31
PL103733B1 (pl) 1979-07-31
NO141050B (no) 1979-09-24
BE834080A (fr) 1976-04-01
CS183821B2 (en) 1978-07-31
US3998875A (en) 1976-12-21
DD125639A5 (xx) 1977-05-04
SU957760A3 (ru) 1982-09-07
NO146198C (no) 1982-08-18
NL7510944A (nl) 1976-04-06
LU73496A1 (xx) 1976-08-19
JPS51105049A (en) 1976-09-17
YU141481A (en) 1982-02-28
SU860695A1 (ru) 1981-08-30
AT344154B (de) 1978-07-10
CS183850B2 (en) 1978-07-31
YU239875A (en) 1982-06-30
FR2286817A1 (fr) 1976-04-30
FI752573A (xx) 1976-04-03
NO753179L (xx) 1976-04-05
SU995705A3 (ru) 1983-02-07
FI61690B (fi) 1982-05-31
ES441404A1 (es) 1977-03-01
CH615158A5 (xx) 1980-01-15
PL103093B1 (pl) 1979-05-31
SE7510329L (sv) 1976-04-05
NO141050C (no) 1980-01-02
DK416975A (da) 1976-04-03

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: MERCK & CO., INC.