FI59102C - Foerfarande foer framstaellning av nya terapeutiskt effektiva piperazinyliminorifamycinfoereningar - Google Patents

Foerfarande foer framstaellning av nya terapeutiskt effektiva piperazinyliminorifamycinfoereningar Download PDF

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Publication number
FI59102C
FI59102C FI760561A FI760561A FI59102C FI 59102 C FI59102 C FI 59102C FI 760561 A FI760561 A FI 760561A FI 760561 A FI760561 A FI 760561A FI 59102 C FI59102 C FI 59102C
Authority
FI
Finland
Prior art keywords
cyclopentyl
rifampicin
derivative
effective
compound
Prior art date
Application number
FI760561A
Other languages
English (en)
Finnish (fi)
Other versions
FI760561A (sl
FI59102B (fi
Inventor
Renato Cricchio
Vittorio Arioli
Original Assignee
Lepetit Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lepetit Spa filed Critical Lepetit Spa
Publication of FI760561A publication Critical patent/FI760561A/fi
Application granted granted Critical
Publication of FI59102B publication Critical patent/FI59102B/fi
Publication of FI59102C publication Critical patent/FI59102C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI760561A 1975-03-05 1976-03-05 Foerfarande foer framstaellning av nya terapeutiskt effektiva piperazinyliminorifamycinfoereningar FI59102C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1002075 1975-03-05
GB10020/75A GB1478563A (en) 1975-03-05 1975-03-05 Rifamycin derivatives

Publications (3)

Publication Number Publication Date
FI760561A FI760561A (sl) 1976-09-06
FI59102B FI59102B (fi) 1981-02-27
FI59102C true FI59102C (fi) 1981-06-10

Family

ID=9959968

Family Applications (1)

Application Number Title Priority Date Filing Date
FI760561A FI59102C (fi) 1975-03-05 1976-03-05 Foerfarande foer framstaellning av nya terapeutiskt effektiva piperazinyliminorifamycinfoereningar

Country Status (27)

Country Link
US (1) US4002752A (sl)
JP (1) JPS51113900A (sl)
AR (1) AR210113A1 (sl)
AT (1) AT344896B (sl)
BE (1) BE839255A (sl)
CA (1) CA1057748A (sl)
CH (1) CH610325A5 (sl)
DD (1) DD123888A5 (sl)
DE (1) DE2608218C3 (sl)
DK (1) DK136655B (sl)
ES (1) ES445790A1 (sl)
FI (1) FI59102C (sl)
FR (1) FR2302742A1 (sl)
GB (1) GB1478563A (sl)
HK (1) HK35282A (sl)
HU (1) HU170451B (sl)
IE (1) IE42881B1 (sl)
KE (1) KE3099A (sl)
LU (1) LU74478A1 (sl)
MX (1) MX3737E (sl)
NL (1) NL165745C (sl)
NO (1) NO143796C (sl)
PT (1) PT64866B (sl)
SE (1) SE420728B (sl)
SU (1) SU575030A3 (sl)
YU (1) YU39477B (sl)
ZA (1) ZA761043B (sl)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2728869A1 (de) * 1976-06-25 1977-12-29 Antibiotice Iasi Intreprindere Rifamycinen und verfahren zu deren herstellung
GR64108B (en) * 1977-04-15 1980-01-24 Dso Pharmachim Method for the preparation of azomethine-derivatives of rifamycin s.v
GB1576886A (en) * 1977-04-20 1980-10-15 Lepetit Spa Rifamycin derivatives
GB1594134A (en) * 1977-11-25 1981-07-30 Holco Investment Inc Rifamycins
AU536524B2 (en) * 1979-06-28 1984-05-10 Gruppo Lepetit S.P.A. Water soluble hydrozones of 3-formylifamyan
US4447432A (en) * 1981-11-17 1984-05-08 Farmitalia Carlo Erba S.P.A. Azino rifamycins
US4681938A (en) * 1984-08-27 1987-07-21 Ciba-Geigy Corporation Novel polycyclic hydrazones of rifamycins, their manufacture, and their pharmaceutical compositions for treating tuberculosis
JPS63501712A (ja) * 1985-10-18 1988-07-14 チバ−ガイギ− アクチエンゲゼルシヤフト 置換４−ベンジルピペラジニル化合物
JPH02501301A (ja) * 1987-09-25 1990-05-10 チバ‐ガイギー　アクチェンゲゼルシャフト ４‐（トリアルキルベンジル）‐ピペラジニル化合物のジアシル誘導体
GB8816620D0 (en) * 1988-07-13 1988-08-17 Lepetit Spa Rifapentine hydrohalides
EP0536197B1 (en) * 1990-06-29 1995-07-26 GRUPPO LEPETIT S.p.A. Pure crystalline form of rifapentine
JP5368092B2 (ja) 2005-08-11 2013-12-18 ターガンタ セラピュティクス，インコーポレイティド ホスホン化リファマイシン類および骨と関節感染の予防と治療のためのその投与法
WO2010019511A2 (en) 2008-08-13 2010-02-18 Targanta Therapeutics Corp. Phosphonated rifamycins and uses thereof for the prevention and treatment of bone and joint infections
RU2496475C2 (ru) 2011-10-26 2013-10-27 Александр Васильевич Иващенко Фармацевтическая композиция и набор для лечения бактериальных инфекций
EA029363B1 (ru) 2012-08-13 2018-03-30 Адифарм Еад Фармацевтические составы, содержащие 3-(4-циннамил-1-пиперазинил)аминопроизводные 3-формил рифамицина sv и 3-формил рифамицина s, и способ их получения
CN103951677B (zh) * 2014-03-17 2016-04-06 四川省长征药业股份有限公司 利福喷丁的制备方法
WO2022225384A1 (es) * 2021-04-21 2022-10-27 Interquim, S.A. De C.V. Proceso de obtención de rifapentina. con una nueva forma cristalina
CN115047122B (zh) * 2022-06-29 2023-05-02 重庆华邦胜凯制药有限公司 利福喷丁及其合成过程中所产生的杂质的分析方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR208F (sl) * 1964-07-31
AR205434A1 (es) * 1972-03-27 1976-05-07 Lepetit Spa Proceso para la preparacion de 3-acilhidrazonometil rifamicinas sv
GB1392272A (en) * 1972-05-31 1975-04-30 Lepetit Spa 3-formylrifamycin azines

Also Published As

Publication number Publication date
JPS51113900A (en) 1976-10-07
DK136655B (da) 1977-11-07
ES445790A1 (es) 1977-06-01
DK136655C (sl) 1978-04-17
NL165745C (nl) 1981-05-15
AU1170476A (en) 1977-09-08
KE3099A (en) 1981-02-13
HK35282A (en) 1982-08-13
BE839255A (fr) 1976-09-06
JPS5530797B2 (sl) 1980-08-13
NL165745B (nl) 1980-12-15
NO143796C (no) 1981-04-15
SE7602122L (sv) 1976-09-06
US4002752A (en) 1977-01-11
DE2608218B2 (de) 1981-02-26
IE42881B1 (en) 1980-11-05
AR210113A1 (es) 1977-06-30
MX3737E (es) 1981-06-05
YU57276A (en) 1982-06-30
CH610325A5 (sl) 1979-04-12
FR2302742B1 (sl) 1979-10-12
AT344896B (de) 1978-08-10
FR2302742A1 (fr) 1976-10-01
ATA162876A (de) 1977-12-15
SU575030A3 (ru) 1977-09-30
DE2608218A1 (de) 1976-09-16
NO143796B (no) 1981-01-05
NO760549L (sl) 1976-09-07
DE2608218C3 (de) 1981-12-10
DD123888A5 (sl) 1977-01-19
IE42881L (en) 1976-09-05
PT64866A (en) 1976-04-01
CA1057748A (en) 1979-07-03
FI760561A (sl) 1976-09-06
DK78476A (sl) 1976-09-06
YU39477B (en) 1984-12-31
NL7602191A (nl) 1976-09-07
LU74478A1 (sl) 1976-09-01
ZA761043B (en) 1977-01-26
GB1478563A (en) 1977-07-06
FI59102B (fi) 1981-02-27
HU170451B (sl) 1977-06-28
PT64866B (en) 1977-07-20
SE420728B (sv) 1981-10-26

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MA Patent expired
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Owner name: GRUPPO LEPETIT S.P.A