FI57259C - Foerfarande foer framstaellning av bronkolytiska och sekretolytiska 6,11-dihydro-6-metyl-5h-pyrido/2,3-b//1,5/benzodiazepin-5-oner och 5,11-dihydro-5-metyl-6h-pyrido/2,3-b//1,4/benzodiazepin-6-oner - Google Patents

Foerfarande foer framstaellning av bronkolytiska och sekretolytiska 6,11-dihydro-6-metyl-5h-pyrido/2,3-b//1,5/benzodiazepin-5-oner och 5,11-dihydro-5-metyl-6h-pyrido/2,3-b//1,4/benzodiazepin-6-oner Download PDF

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Publication number
FI57259C
FI57259C FI751470A FI751470A FI57259C FI 57259 C FI57259 C FI 57259C FI 751470 A FI751470 A FI 751470A FI 751470 A FI751470 A FI 751470A FI 57259 C FI57259 C FI 57259C
Authority
FI
Finland
Prior art keywords
pyrido
dihydro
methyl
benzodiazepin
general formula
Prior art date
Application number
FI751470A
Other languages
English (en)
Finnish (fi)
Other versions
FI57259B (fi
FI751470A (xx
Inventor
Guenther Schmidt
Guenther Engelhardt
Sigfrid Pueschmann
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of FI751470A publication Critical patent/FI751470A/fi
Publication of FI57259B publication Critical patent/FI57259B/fi
Application granted granted Critical
Publication of FI57259C publication Critical patent/FI57259C/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
FI751470A 1974-05-22 1975-05-20 Foerfarande foer framstaellning av bronkolytiska och sekretolytiska 6,11-dihydro-6-metyl-5h-pyrido/2,3-b//1,5/benzodiazepin-5-oner och 5,11-dihydro-5-metyl-6h-pyrido/2,3-b//1,4/benzodiazepin-6-oner FI57259C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2424811A DE2424811C3 (de) 1974-05-22 1974-05-22 Pyrido-benzodiazepinone, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
DE2424811 1974-05-22

Publications (3)

Publication Number Publication Date
FI751470A FI751470A (xx) 1975-11-23
FI57259B FI57259B (fi) 1980-03-31
FI57259C true FI57259C (fi) 1980-07-10

Family

ID=5916217

Family Applications (1)

Application Number Title Priority Date Filing Date
FI751470A FI57259C (fi) 1974-05-22 1975-05-20 Foerfarande foer framstaellning av bronkolytiska och sekretolytiska 6,11-dihydro-6-metyl-5h-pyrido/2,3-b//1,5/benzodiazepin-5-oner och 5,11-dihydro-5-metyl-6h-pyrido/2,3-b//1,4/benzodiazepin-6-oner

Country Status (27)

Country Link
US (1) US4021557A (xx)
JP (1) JPS5224038B2 (xx)
AT (1) AT342058B (xx)
BE (1) BE829327A (xx)
BG (3) BG24807A3 (xx)
CH (3) CH617694A5 (xx)
CS (1) CS191264B2 (xx)
DD (1) DD117459A5 (xx)
DE (1) DE2424811C3 (xx)
DK (1) DK139724C (xx)
ES (3) ES437423A1 (xx)
FI (1) FI57259C (xx)
FR (1) FR2271831B1 (xx)
GB (1) GB1456627A (xx)
HU (1) HU173786B (xx)
IE (1) IE41244B1 (xx)
IL (1) IL47329A (xx)
LU (1) LU72560A1 (xx)
NL (1) NL7506008A (xx)
NO (1) NO141894C (xx)
PH (1) PH13405A (xx)
PL (3) PL98614B1 (xx)
RO (2) RO71575A (xx)
SE (1) SE421921B (xx)
SU (3) SU578878A3 (xx)
YU (1) YU130775A (xx)
ZA (1) ZA753272B (xx)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2644121A1 (de) * 1976-09-30 1978-04-06 Thomae Gmbh Dr K Neue pyridobenzodiazepinone, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
EP0024582A1 (de) * 1979-08-10 1981-03-11 Byk Gulden Lomberg Chemische Fabrik GmbH Benzodiazepinone, Verfahren zu ihrer Herstellung sowie sie enthaltende Arzneimittel
IL62792A (en) * 1980-05-07 1985-02-28 Byk Gulden Lomberg Chem Fab Acylated dihydrothienodiazepinone compounds,process for their preparation,and medicaments containing them
US4381301A (en) * 1980-05-07 1983-04-26 Byk Gulden Lomberg Chemische Fabrik Gmbh Substituted tricyclic thieno compounds, their synthesis, their use, their compositions and their medicaments
DE3280227D1 (de) * 1981-09-24 1990-09-20 Robins Co Inc A H Phenyl-substituierte pyrido(1,4)benzodiazepine und zwischenverbindungen.
SE448629B (sv) * 1981-09-24 1987-03-09 Robins Co Inc A H Pyrido/1,4/bensodiazepiner
DE3643666A1 (de) * 1986-12-20 1988-06-30 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
ATE161535T1 (de) * 1989-04-20 1998-01-15 Boehringer Ingelheim Pharma 6,11-dihydro-5h-pyrido(2,3-b)(1,5)benzodiazepin 5-one und thione und ihre verwendung für die vorbeugung oder behandlung von aids
CA2052946A1 (en) * 1990-10-19 1992-04-20 Karl G. Grozinger Method for the preparation of 5,11-dihydro-6h-dipyrido ¬3,2-b:2', 3'-e| ¬1,4|diazepines
FR2850654A1 (fr) * 2003-02-03 2004-08-06 Servier Lab Nouveaux derives d'azepines tricycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
WO2006008118A1 (en) 2004-07-16 2006-01-26 Proteosys Ag Muscarinic antagonists with parp and sir modulating activity as cytoprotective agents
EP2379080A1 (en) 2009-01-13 2011-10-26 ProteoSys AG Pirenzepine as otoprotective agent

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3316249A (en) * 1967-04-25 Part a.xmethyl n n-(z-diethylaminoethyl)-n-(z- nitrophenyl) anthranilate hydrochloride
FR1505795A (fr) * 1965-12-17 1967-12-15 Thomae Gmbh Dr K Procédé pour fabriquer de nouvelles 11h-pyrido[2, 3-b][1, 5]benzodiazépine-5(6h)-ones substituées en position 11
FI49509C (fi) * 1968-08-20 1975-07-10 Thomae Gmbh Dr K Menetelmä farmakologisesti vaikuttavien 5-asemaan substituoitujen 5,10 -dihydro-11H-dibentso/b,e//1,4/deatsepiini-11-onien ja niiden suolojen valmistamiseksi.
DE1795183B1 (de) * 1968-08-20 1972-07-20 Thomae Gmbh Dr K 5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-on-derivate und Arzneimittel
AT327200B (de) * 1972-09-06 1976-01-26 Degussa Verfahren zur herstellung von neuen aza-10,11-dihydro-5h-dibenzo (b,e)-(1,4) diazepinen sowie deren salzen

Also Published As

Publication number Publication date
JPS5224038B2 (xx) 1977-06-28
GB1456627A (en) 1976-11-24
CH617698A5 (xx) 1980-06-13
SE421921B (sv) 1982-02-08
DK139724B (da) 1979-04-02
PL100079B1 (pl) 1978-08-31
DD117459A5 (xx) 1976-01-12
SU587864A3 (ru) 1978-01-05
ATA267475A (de) 1977-07-15
JPS50160298A (xx) 1975-12-25
ES441591A1 (es) 1977-04-16
RO66914A (ro) 1981-07-30
CH617699A5 (xx) 1980-06-13
BE829327A (fr) 1975-11-21
CS191264B2 (en) 1979-06-29
NL7506008A (nl) 1975-11-25
DK139724C (da) 1979-09-17
CH617694A5 (xx) 1980-06-13
NO751801L (xx) 1975-11-25
DE2424811C3 (de) 1981-08-20
NO141894B (no) 1980-02-18
FI57259B (fi) 1980-03-31
NO141894C (no) 1980-06-04
DK223175A (da) 1975-11-23
PL98951B1 (xx) 1978-06-30
HU173786B (hu) 1979-08-28
PL98614B1 (pl) 1978-05-31
ES437423A1 (es) 1977-04-16
DE2424811A1 (de) 1975-12-18
ZA753272B (en) 1977-01-26
FI751470A (xx) 1975-11-23
AT342058B (de) 1978-03-10
RO71575A (ro) 1982-02-26
DE2424811B2 (de) 1980-10-02
BG23541A3 (xx) 1977-09-15
PH13405A (en) 1980-03-28
FR2271831A1 (xx) 1975-12-19
SE7505796L (sv) 1975-11-24
YU130775A (en) 1982-06-30
IL47329A (en) 1978-04-30
US4021557A (en) 1977-05-03
IE41244B1 (en) 1979-11-21
SU567407A3 (ru) 1977-07-30
LU72560A1 (xx) 1977-02-10
BG24807A3 (en) 1978-05-12
BG23901A3 (en) 1977-11-10
IL47329A0 (en) 1975-07-28
FR2271831B1 (xx) 1979-06-08
ES441592A1 (es) 1977-04-01
SU578878A3 (ru) 1977-10-30
IE41244L (en) 1975-11-22

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Owner name: DR. KARL THOMAE GESELLSCHAFT