FI57106C - Foerfarande foer framstaellning av dibenso(c,f)-pyrazino(1,2-a)-azepinderivat - Google Patents

Foerfarande foer framstaellning av dibenso(c,f)-pyrazino(1,2-a)-azepinderivat Download PDF

Info

Publication number
FI57106C
FI57106C FI750327A FI750327A FI57106C FI 57106 C FI57106 C FI 57106C FI 750327 A FI750327 A FI 750327A FI 750327 A FI750327 A FI 750327A FI 57106 C FI57106 C FI 57106C
Authority
FI
Finland
Prior art keywords
formula
pyrazino
compound
halogen
hydroxy group
Prior art date
Application number
FI750327A
Other languages
English (en)
Finnish (fi)
Other versions
FI57106B (fi
FI750327A (no
Inventor
Jacques Olivie
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of FI750327A publication Critical patent/FI750327A/fi
Application granted granted Critical
Publication of FI57106B publication Critical patent/FI57106B/fi
Publication of FI57106C publication Critical patent/FI57106C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/04Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/04Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FI750327A 1974-02-09 1975-02-06 Foerfarande foer framstaellning av dibenso(c,f)-pyrazino(1,2-a)-azepinderivat FI57106C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL7401807 1974-02-09
NLAANVRAGE7401807,A NL179906C (nl) 1974-02-09 1974-02-09 Werkwijze voor het bereiden van 1,2,3,4,10,14b-hexahydrodibenzo(c,f)pyrazino (1,2-a)azepine derivaten.

Publications (3)

Publication Number Publication Date
FI750327A FI750327A (no) 1975-08-10
FI57106B FI57106B (fi) 1980-02-29
FI57106C true FI57106C (fi) 1980-06-10

Family

ID=19820725

Family Applications (1)

Application Number Title Priority Date Filing Date
FI750327A FI57106C (fi) 1974-02-09 1975-02-06 Foerfarande foer framstaellning av dibenso(c,f)-pyrazino(1,2-a)-azepinderivat

Country Status (13)

Country Link
US (2) US4025513A (no)
JP (1) JPS5315520B2 (no)
CA (1) CA1084490A (no)
CH (1) CH613705A5 (no)
DE (1) DE2505239A1 (no)
DK (1) DK150144C (no)
ES (1) ES434533A1 (no)
FI (1) FI57106C (no)
FR (1) FR2260579B1 (no)
GB (2) GB1498633A (no)
HU (1) HU169018B (no)
NL (1) NL179906C (no)
SE (1) SE418745B (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5655174U (no) * 1979-10-06 1981-05-14
EP0088575B1 (en) * 1982-03-05 1986-12-30 Beecham Group Plc Pentacyclic compounds
US4515792A (en) * 1982-09-30 1985-05-07 Ciba-Geigy Corporation Tetracyclic heterocycles and antidepressant compositions thereof
GB2138016B (en) * 1983-04-05 1986-10-29 Bostik Ltd Adhesive bonding
CA2026925A1 (en) * 1989-10-05 1991-04-06 Hiroshi Fukumi Tetracyclic compounds having anti-allergic and anti-asthmatic activities, their preparation and use
EP0539164A1 (en) * 1991-10-23 1993-04-28 Sankyo Company Limited Nitrogen-containing tetracyclic compounds having anti-allergic and anti-asthmatic activities, their preparation and use
DE4305659A1 (de) * 1993-02-24 1994-08-25 Heumann Pharma Gmbh & Co Verfahren zur Herstellung von 1,2,3,4,10,14b-Hexahydro-2-methyl-dibenzo[c,f]pyrazino[1,2-a]azepin und seiner Salze
WO1999016769A1 (en) * 1997-09-26 1999-04-08 Monash University Resolution of optically-active compounds
KR20020015313A (ko) 1999-04-19 2002-02-27 추후보정 피페라진 고리의 신규한 합성방법
AU6476300A (en) 1999-09-30 2001-05-10 Sumika Fine Chemicals Co., Ltd. Process for the preparation of a piperazine derivative
US8461389B2 (en) 2008-04-18 2013-06-11 University College Dublin, National University Of Ireland, Dublin Psycho-pharmaceuticals
CN102649779A (zh) * 2012-04-20 2012-08-29 山东鲁药制药有限公司 一种药物中间体1-甲基-3-苯基哌嗪的合成方法
CN102911793B (zh) * 2012-10-04 2013-10-23 盐城师范学院 一种功能化碱性离子液体及其在生物柴油制备中的应用
CN102876466B (zh) * 2012-10-05 2013-10-23 盐城师范学院 一种碱性离子液体催化酯交换反应的方法
CN104892608B (zh) * 2015-06-29 2017-06-20 山西康宝生物制品股份有限公司 一种米氮醇的合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3190893A (en) * 1961-02-17 1965-06-22 Kefalas As Method of producing 9, 10-dihydroanthracenes
CH420150A (de) * 1961-12-18 1966-09-15 Siegfried Ag Verfahren zur Herstellung von 10-Aminoalkyl-5,5-dialkylacridanen
NL129434C (no) * 1966-03-12
US3808208A (en) * 1970-02-02 1974-04-30 Dow Chemical Co P-benzodithino(dioxino)(2,3,-b)pyrazines
NL176458C (nl) * 1972-09-23 1985-04-16 Akzo Nv Werkwijze ter bereiding van een farmaceutisch preparaat en werkwijze voor de bereiding van daartoe geschikte actieve stoffen.
DE2457971A1 (de) * 1974-12-07 1976-06-10 Merck Patent Gmbh Verfahren zur herstellung von 2-acyl4-oxo-pyrazino-isochinolin-derivaten

Also Published As

Publication number Publication date
FR2260579B1 (no) 1977-07-08
SE7501365L (no) 1975-08-11
DK32375A (no) 1975-09-29
US4254031A (en) 1981-03-03
US4025513A (en) 1977-05-24
CA1084490A (en) 1980-08-26
JPS50108299A (no) 1975-08-26
DK150144C (da) 1987-10-19
ES434533A1 (es) 1976-12-01
SE418745B (sv) 1981-06-22
JPS5315520B2 (no) 1978-05-25
FR2260579A1 (no) 1975-09-05
NL179906C (nl) 1986-12-01
DK150144B (da) 1986-12-15
DE2505239A1 (de) 1975-08-14
GB1498633A (en) 1978-01-25
HU169018B (no) 1976-09-28
NL7401807A (nl) 1975-08-12
DE2505239C2 (no) 1988-11-03
GB1498632A (en) 1978-01-25
FI57106B (fi) 1980-02-29
FI750327A (no) 1975-08-10
CH613705A5 (no) 1979-10-15

Similar Documents

Publication Publication Date Title
FI57106C (fi) Foerfarande foer framstaellning av dibenso(c,f)-pyrazino(1,2-a)-azepinderivat
Thompson et al. Synthesis and pharmacological evaluation of a series of dibenzo [a, d] cycloalkenimines as N-methyl-D-aspartate antagonists
FI77455C (fi) Foerfarande foer framstaellning av antihypertensiva 2,4-diaminokinazolinfoereningar.
FI69839B (fi) Foerfarande foer framstaellning av terapeutiskt aktiva difenylmetoxialkylpiperazinderivat
DK142498B (da) Analogifremgangsmåde til fremstilling af benzopyridoazepinderivater.
CH637382A5 (de) Verfahren zur herstellung neuer tetracyclischer pyridin- oder pyrrolderivate.
US3192204A (en) Trifluoromethylthiaxanthene and -xanthene derivatives
FI70006B (fi) Saosom mellanprodukter vid framstaellning av n-alkylerade 9-aminoalkyl-9-aminokarbonylfluorenderivat anvaendbara 9-aminoalkyl-9-aminokarbonylfluorener
FI60563C (fi) Foerfarande foer framstaellning av nya terapeutiskt anvaendbara tetracykliska piperidinoderivat
US3118884A (en) Derivatives of 3-azaphenothiazine and 3-azaphenoxazine
US4249002A (en) Polycyclic amines and intermediates therefor
FI60866C (fi) Foerfarande foer framstaellning av 4-oxo-1,2,3,6,7,11b-hexahydro-4h-pyrazino-(2,1-a)isokinoliner vilka aer mellanprodukter vid framstaellning av 2-acyl-4-oxo-1,2,3,6,7,11b-hexahydro-4h-pyrazino(2,1-a)isokinoliner anvaendbara saosom antihelmintika
US3341528A (en) Substituted benzoquinolines
US4217452A (en) Synthesis for the preparation of tetracyclic compounds
FI85466B (fi) Foerfarande foer framstaellning av foer behandling av spasmodiska tillstaond och allergier anvaendbara benzhydryloxietylpiperidinderivat.
US3131190A (en) 9-aminoalkyl and 9-aminoalkylidene derivatives of acridan
US3370058A (en) 5-acyl morphanthridine derivatives
FI63566C (fi) Foerfarande foer framstaellning av nya terapeutiskt anvaendbara dibenso(d g)(1,3,6)dioxazocin-derivat och av deras fysiologiskt godtagbara syraadditionssalter
DK150143B (da) Analogifremgangsmaade til fremstilling af indolderivater
US5854273A (en) Bisimide compounds
US4927970A (en) Substituted 3-cyclobutene-1,2-dione intermediates
FI77032C (fi) Foerfarande foer framstaellning av 6-fenyl-11h-pyrido/2,3-b//1,4/bensodiazepiner.
US4022780A (en) Process for the manufacture of indole derivatives
FI63578B (fi) Analogifoerfarande foer framstaellning av nya farmakologiskt verksamma 1,3,4,14b-tetrahydro-2h,10h-pyrazino(1,2-a)pyrrolo(2,1-c)(1,4)bensodiazepiner
AU603081B2 (en) Symmetrical O-substituted dioximes of benzo-fused beta- diketocycloalkylenes, the processes for their preparation and their application as drugs

Legal Events

Date Code Title Description
MA Patent expired
MA Patent expired

Owner name: AKZO N.V.