FI52089C - Tapa valmistaa terapeuttisesti vaikuttavia cis-bentso/c//1,6/naftyridi ini-johdannaisia. - Google Patents

Tapa valmistaa terapeuttisesti vaikuttavia cis-bentso/c//1,6/naftyridi ini-johdannaisia.

Info

Publication number
FI52089C
FI52089C FI129371A FI129371A FI52089C FI 52089 C FI52089 C FI 52089C FI 129371 A FI129371 A FI 129371A FI 129371 A FI129371 A FI 129371A FI 52089 C FI52089 C FI 52089C
Authority
FI
Finland
Prior art keywords
benzo
preparation
therapeutically active
naphthyridine derivatives
active cis
Prior art date
Application number
FI129371A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI52089B (cs
Inventor
Hans Ott
Rudolf Sueess
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH708970A external-priority patent/CH527822A/de
Priority claimed from CH708670A external-priority patent/CH527196A/de
Application filed by Sandoz Ag filed Critical Sandoz Ag
Application granted granted Critical
Publication of FI52089B publication Critical patent/FI52089B/fi
Publication of FI52089C publication Critical patent/FI52089C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • C07D211/58Nitrogen atoms attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI129371A 1970-05-13 1971-05-11 Tapa valmistaa terapeuttisesti vaikuttavia cis-bentso/c//1,6/naftyridi ini-johdannaisia. FI52089C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH708970A CH527822A (de) 1970-05-13 1970-05-13 Verfahren zur Herstellung neuer Benzonaphtyridin-Derivate
CH708670A CH527196A (de) 1970-05-13 1970-05-13 Verfahren zur Herstellung neuer Benzonaphthyridinderivate

Publications (2)

Publication Number Publication Date
FI52089B FI52089B (cs) 1977-02-28
FI52089C true FI52089C (fi) 1977-06-10

Family

ID=25700728

Family Applications (1)

Application Number Title Priority Date Filing Date
FI129371A FI52089C (fi) 1970-05-13 1971-05-11 Tapa valmistaa terapeuttisesti vaikuttavia cis-bentso/c//1,6/naftyridi ini-johdannaisia.

Country Status (14)

Country Link
JP (1) JPS5432799B1 (cs)
AT (1) AT326674B (cs)
CA (1) CA970377A (cs)
CS (2) CS167202B2 (cs)
DE (1) DE2123328A1 (cs)
DK (1) DK134488B (cs)
ES (1) ES391026A1 (cs)
FI (1) FI52089C (cs)
FR (1) FR2100649B1 (cs)
GB (1) GB1361441A (cs)
NL (1) NL7106502A (cs)
PL (1) PL76913B1 (cs)
SE (1) SE387640B (cs)
SU (1) SU423296A3 (cs)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3899494A (en) * 1970-05-13 1975-08-12 Sandoz Ltd Substituted 6-phenyl benzo-naphthyridines
NL7314396A (cs) * 1972-10-26 1974-05-01
BE880455A (fr) * 1979-01-22 1980-06-06 Sandoz Sa Compositions pharmaceutiques a base d'une benzo (c) (1,6) naphtyridine
ES2193539T3 (es) * 1997-06-03 2003-11-01 Altana Pharma Ag Benzonaftiridinas.
NZ517166A (en) 1999-08-21 2004-01-30 Altana Pharma Ag Synergistic combination of PDE inhibitors and beta 2 adrenoceptor agonists
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
EP1624893A2 (en) 2003-04-01 2006-02-15 Applied Research Systems ARS Holding N.V. Inhibitors of phosphodiesterases in infertility
BRPI0510951A (pt) * 2004-05-12 2007-11-20 Pfizer Prod Inc derivados de piperidina como antagonistas de nk1 e nk3
AU2008261102B2 (en) 2007-06-04 2013-11-28 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8034782B2 (en) 2008-07-16 2011-10-11 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
CA2930674A1 (en) 2008-06-04 2009-12-10 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
EP2681236B1 (en) 2011-03-01 2018-01-03 Synergy Pharmaceuticals Inc. Process of preparing guanylate cyclase c agonists
JP6499591B2 (ja) 2013-02-25 2019-04-10 シナジー ファーマシューティカルズ インコーポレイテッド 結腸洗浄において用いるためのグアニル酸シクラーゼ受容体アゴニスト
AU2014235215A1 (en) 2013-03-15 2015-10-01 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
EP2968439A2 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
CN113388007A (zh) 2013-06-05 2021-09-14 博士医疗爱尔兰有限公司 鸟苷酸环化酶c的超纯激动剂、制备和使用所述激动剂的方法
MX375926B (es) 2013-08-09 2025-03-07 Ardelyx Inc Compuestos y metodos para inhibir el transporte de fosfato.
EP3972599B1 (en) 2019-05-21 2025-10-22 Ardelyx, Inc. Combination for lowering serum phosphate in a patient

Also Published As

Publication number Publication date
CS167202B2 (cs) 1976-04-29
DE2123328A1 (de) 1971-12-02
SU423296A3 (ru) 1974-04-05
NL7106502A (cs) 1971-11-16
ATA412471A (de) 1975-03-15
DK134488B (da) 1976-11-15
FR2100649B1 (cs) 1974-08-30
CA970377A (en) 1975-07-01
GB1361441A (en) 1974-07-24
FR2100649A1 (cs) 1972-03-24
PL76913B1 (en) 1975-02-28
CS162753B2 (cs) 1975-07-15
AT326674B (de) 1975-12-29
FI52089B (cs) 1977-02-28
JPS5432799B1 (cs) 1979-10-16
SE387640B (sv) 1976-09-13
DK134488C (cs) 1977-05-16
ES391026A1 (es) 1974-04-01

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