FI52089C - A process for the preparation of therapeutically active cis-benzo [c] -1,6 / naphthyridine derivatives. - Google Patents

A process for the preparation of therapeutically active cis-benzo [c] -1,6 / naphthyridine derivatives.

Info

Publication number
FI52089C
FI52089C FI129371A FI129371A FI52089C FI 52089 C FI52089 C FI 52089C FI 129371 A FI129371 A FI 129371A FI 129371 A FI129371 A FI 129371A FI 52089 C FI52089 C FI 52089C
Authority
FI
Finland
Prior art keywords
benzo
preparation
therapeutically active
naphthyridine derivatives
active cis
Prior art date
Application number
FI129371A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI52089B (en
Inventor
Hans Ott
Rudolf Sueess
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH708670A external-priority patent/CH527196A/en
Priority claimed from CH708970A external-priority patent/CH527822A/en
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of FI52089B publication Critical patent/FI52089B/fi
Application granted granted Critical
Publication of FI52089C publication Critical patent/FI52089C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI129371A 1970-05-13 1971-05-11 A process for the preparation of therapeutically active cis-benzo [c] -1,6 / naphthyridine derivatives. FI52089C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH708670A CH527196A (en) 1970-05-13 1970-05-13 Process for the preparation of new benzonaphthyridine derivatives
CH708970A CH527822A (en) 1970-05-13 1970-05-13 Cis-1,2,,3,4,4a-10b-hexahydro-2-methyl-6-phenyl benzo - (c) (1,6) naphthyridine derivs

Publications (2)

Publication Number Publication Date
FI52089B FI52089B (en) 1977-02-28
FI52089C true FI52089C (en) 1977-06-10

Family

ID=25700728

Family Applications (1)

Application Number Title Priority Date Filing Date
FI129371A FI52089C (en) 1970-05-13 1971-05-11 A process for the preparation of therapeutically active cis-benzo [c] -1,6 / naphthyridine derivatives.

Country Status (14)

Country Link
JP (1) JPS5432799B1 (en)
AT (1) AT326674B (en)
CA (1) CA970377A (en)
CS (2) CS162753B2 (en)
DE (1) DE2123328A1 (en)
DK (1) DK134488B (en)
ES (1) ES391026A1 (en)
FI (1) FI52089C (en)
FR (1) FR2100649B1 (en)
GB (1) GB1361441A (en)
NL (1) NL7106502A (en)
PL (1) PL76913B1 (en)
SE (1) SE387640B (en)
SU (1) SU423296A3 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3899494A (en) * 1970-05-13 1975-08-12 Sandoz Ltd Substituted 6-phenyl benzo-naphthyridines
NL7314396A (en) * 1972-10-26 1974-05-01
BE880455A (en) * 1979-01-22 1980-06-06 Sandoz Sa PHARMACEUTICAL COMPOSITIONS BASED ON A BENZO (C) (1,6) NAPHTYRIDINE
JP2002502403A (en) 1997-06-03 2002-01-22 ビイク グルデン ロンベルク ヒエーミツシエ フアブリーク ゲゼルシヤフト ミツト ベシユレンクテル ハフツング Benzonaphthyridine
PT1212089E (en) 1999-08-21 2006-08-31 Altana Pharma Ag ROFLUMILAST AND SALMETEROL SYNERGY COMBINATION
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
JP2006522151A (en) 2003-04-01 2006-09-28 アプライド リサーチ システムズ エーアールエス ホールディング ナームロゼ フェンノートシャップ Phosphodiesterase inhibitors in infertility
JP2007537233A (en) * 2004-05-12 2007-12-20 ファイザー・プロダクツ・インク Piperidine derivatives as NK1 and NK3 antagonists
US20100120694A1 (en) 2008-06-04 2010-05-13 Synergy Pharmaceuticals, Inc. Agonists of Guanylate Cyclase Useful for the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and Other Disorders
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
CA3089569C (en) 2007-06-04 2023-12-05 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
EP2321341B1 (en) 2008-07-16 2017-02-22 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CN108676076A (en) 2011-03-01 2018-10-19 辛纳吉制药公司 The method for preparing guanosine cyclic mono-phosphate agonist
JP6499591B2 (en) 2013-02-25 2019-04-10 シナジー ファーマシューティカルズ インコーポレイテッド Guanylate cyclase receptor agonists for use in colon lavage
EP2970384A1 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
JP2016514670A (en) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド Guanylate cyclase receptor agonists in combination with other drugs
RS65632B1 (en) 2013-06-05 2024-07-31 Bausch Health Ireland Ltd Ultra-pure agonists of guanylate cyclase c, method of making and using same
WO2015021358A2 (en) 2013-08-09 2015-02-12 Dominique Charmot Compounds and methods for inhibiting phosphate transport
JP2022533251A (en) 2019-05-21 2022-07-21 アルデリックス， インコーポレイテッド Combinations to lower serum phosphate in patients

Also Published As

Publication number Publication date
FR2100649A1 (en) 1972-03-24
DK134488C (en) 1977-05-16
FI52089B (en) 1977-02-28
CS167202B2 (en) 1976-04-29
AT326674B (en) 1975-12-29
SE387640B (en) 1976-09-13
GB1361441A (en) 1974-07-24
DK134488B (en) 1976-11-15
CS162753B2 (en) 1975-07-15
ES391026A1 (en) 1974-04-01
JPS5432799B1 (en) 1979-10-16
CA970377A (en) 1975-07-01
PL76913B1 (en) 1975-02-28
ATA412471A (en) 1975-03-15
SU423296A3 (en) 1974-04-05
DE2123328A1 (en) 1971-12-02
NL7106502A (en) 1971-11-16
FR2100649B1 (en) 1974-08-30

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