FI52089B - - Google Patents

Info

Publication number
FI52089B
FI52089B FI129371A FI129371A FI52089B FI 52089 B FI52089 B FI 52089B FI 129371 A FI129371 A FI 129371A FI 129371 A FI129371 A FI 129371A FI 52089 B FI52089 B FI 52089B
Authority
FI
Finland
Application number
FI129371A
Other languages
Finnish (fi)
Other versions
FI52089C (en
Inventor
Hans Ott
Rudolf Sueess
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH708670A external-priority patent/CH527196A/en
Priority claimed from CH708970A external-priority patent/CH527822A/en
Application filed by Sandoz Ag filed Critical Sandoz Ag
Application granted granted Critical
Publication of FI52089B publication Critical patent/FI52089B/fi
Publication of FI52089C publication Critical patent/FI52089C/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • C07D211/58Nitrogen atoms attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI129371A 1970-05-13 1971-05-11 A process for the preparation of therapeutically active cis-benzo [c] -1,6 / naphthyridine derivatives. FI52089C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH708670A CH527196A (en) 1970-05-13 1970-05-13 Process for the preparation of new benzonaphthyridine derivatives
CH708970A CH527822A (en) 1970-05-13 1970-05-13 Cis-1,2,,3,4,4a-10b-hexahydro-2-methyl-6-phenyl benzo - (c) (1,6) naphthyridine derivs

Publications (2)

Publication Number Publication Date
FI52089B true FI52089B (en) 1977-02-28
FI52089C FI52089C (en) 1977-06-10

Family

ID=25700728

Family Applications (1)

Application Number Title Priority Date Filing Date
FI129371A FI52089C (en) 1970-05-13 1971-05-11 A process for the preparation of therapeutically active cis-benzo [c] -1,6 / naphthyridine derivatives.

Country Status (14)

Country Link
JP (1) JPS5432799B1 (en)
AT (1) AT326674B (en)
CA (1) CA970377A (en)
CS (2) CS162753B2 (en)
DE (1) DE2123328A1 (en)
DK (1) DK134488B (en)
ES (1) ES391026A1 (en)
FI (1) FI52089C (en)
FR (1) FR2100649B1 (en)
GB (1) GB1361441A (en)
NL (1) NL7106502A (en)
PL (1) PL76913B1 (en)
SE (1) SE387640B (en)
SU (1) SU423296A3 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3899494A (en) * 1970-05-13 1975-08-12 Sandoz Ltd Substituted 6-phenyl benzo-naphthyridines
NL7314396A (en) * 1972-10-26 1974-05-01
BE880455A (en) * 1979-01-22 1980-06-06 Sandoz Sa PHARMACEUTICAL COMPOSITIONS BASED ON A BENZO (C) (1,6) NAPHTYRIDINE
JP2002502403A (en) 1997-06-03 2002-01-22 ビイク グルデン ロンベルク ヒエーミツシエ フアブリーク ゲゼルシヤフト ミツト ベシユレンクテル ハフツング Benzonaphthyridine
SI1212089T1 (en) 1999-08-21 2006-08-31 Altana Pharma Ag Synergistic combination of roflumilast and salmeterol
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
JP2006522151A (en) 2003-04-01 2006-09-28 アプライド リサーチ システムズ エーアールエス ホールディング ナームロゼ フェンノートシャップ Phosphodiesterase inhibitors in infertility
WO2005110987A1 (en) * 2004-05-12 2005-11-24 Pfizer Products Inc. Piperidine derivatives as nk1 and nk3 antagonists
DK2170930T3 (en) 2007-06-04 2012-11-05 Synergy Pharmaceuticals Inc AGONISTS OF GUANYLATCYCLASE USED FOR THE TREATMENT OF GASTROINTESTINAL DISEASES, INFLAMMATION, CANCER AND OTHER DISEASES
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
EP2328910B1 (en) 2008-06-04 2014-08-06 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
ES2624828T3 (en) 2008-07-16 2017-07-17 Synergy Pharmaceuticals Inc. Guanylate cyclase agonists useful for the treatment of gastrointestinal disorders, inflammation, cancer and others
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
JP6251038B2 (en) 2011-03-01 2017-12-20 シナジー ファーマシューティカルズ インコーポレイテッド Method for preparing guanylate cyclase C agonist
US9545446B2 (en) 2013-02-25 2017-01-17 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase and their uses
US9486494B2 (en) 2013-03-15 2016-11-08 Synergy Pharmaceuticals, Inc. Compositions useful for the treatment of gastrointestinal disorders
CA2905438A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
JP6606491B2 (en) 2013-06-05 2019-11-13 シナジー ファーマシューティカルズ インコーポレイテッド Ultra high purity agonist of guanylate cyclase C, method for producing and using the same
AU2014305843B2 (en) 2013-08-09 2019-08-29 Ardelyx, Inc. Compounds and methods for inhibiting phosphate transport
US20200368223A1 (en) 2019-05-21 2020-11-26 Ardelyx, Inc. Methods for inhibiting phosphate transport

Also Published As

Publication number Publication date
ATA412471A (en) 1975-03-15
FI52089C (en) 1977-06-10
DE2123328A1 (en) 1971-12-02
SU423296A3 (en) 1974-04-05
FR2100649B1 (en) 1974-08-30
GB1361441A (en) 1974-07-24
DK134488B (en) 1976-11-15
DK134488C (en) 1977-05-16
NL7106502A (en) 1971-11-16
PL76913B1 (en) 1975-02-28
CS167202B2 (en) 1976-04-29
CS162753B2 (en) 1975-07-15
ES391026A1 (en) 1974-04-01
AT326674B (en) 1975-12-29
CA970377A (en) 1975-07-01
SE387640B (en) 1976-09-13
JPS5432799B1 (en) 1979-10-16
FR2100649A1 (en) 1972-03-24

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