CA970377A - Benzonaphthyridine derivatives - Google Patents

Benzonaphthyridine derivatives

Info

Publication number
CA970377A
CA970377A CA112,767A CA112767A CA970377A CA 970377 A CA970377 A CA 970377A CA 112767 A CA112767 A CA 112767A CA 970377 A CA970377 A CA 970377A
Authority
CA
Canada
Prior art keywords
benzonaphthyridine derivatives
benzonaphthyridine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA112,767A
Other languages
English (en)
Inventor
Hans Ott
Rudolf Suess
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz Patent Ltd
Original Assignee
Sandoz Patent Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH708670A external-priority patent/CH527196A/de
Priority claimed from CH708970A external-priority patent/CH527822A/de
Application filed by Sandoz Patent Ltd filed Critical Sandoz Patent Ltd
Application granted granted Critical
Publication of CA970377A publication Critical patent/CA970377A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • C07D211/58Nitrogen atoms attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA112,767A 1970-05-13 1971-05-12 Benzonaphthyridine derivatives Expired CA970377A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH708670A CH527196A (de) 1970-05-13 1970-05-13 Verfahren zur Herstellung neuer Benzonaphthyridinderivate
CH708970A CH527822A (de) 1970-05-13 1970-05-13 Verfahren zur Herstellung neuer Benzonaphtyridin-Derivate

Publications (1)

Publication Number Publication Date
CA970377A true CA970377A (en) 1975-07-01

Family

ID=25700728

Family Applications (1)

Application Number Title Priority Date Filing Date
CA112,767A Expired CA970377A (en) 1970-05-13 1971-05-12 Benzonaphthyridine derivatives

Country Status (14)

Country Link
JP (1) JPS5432799B1 (cs)
AT (1) AT326674B (cs)
CA (1) CA970377A (cs)
CS (2) CS162753B2 (cs)
DE (1) DE2123328A1 (cs)
DK (1) DK134488B (cs)
ES (1) ES391026A1 (cs)
FI (1) FI52089C (cs)
FR (1) FR2100649B1 (cs)
GB (1) GB1361441A (cs)
NL (1) NL7106502A (cs)
PL (1) PL76913B1 (cs)
SE (1) SE387640B (cs)
SU (1) SU423296A3 (cs)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3899494A (en) * 1970-05-13 1975-08-12 Sandoz Ltd Substituted 6-phenyl benzo-naphthyridines
NL7314396A (cs) * 1972-10-26 1974-05-01
BE880455A (fr) * 1979-01-22 1980-06-06 Sandoz Sa Compositions pharmaceutiques a base d'une benzo (c) (1,6) naphtyridine
US6384047B1 (en) 1997-06-03 2002-05-07 Byk Gulden Lomberg Chemische Fabrik Gmbh Benzonaphthyridine
BRPI0013478B8 (pt) 1999-08-21 2016-12-27 Altana Pharma Ag medicamento compreendendo inibidor pde e uso de roflumilast
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
JP2006522151A (ja) 2003-04-01 2006-09-28 アプライド リサーチ システムズ エーアールエス ホールディング ナームロゼ フェンノートシャップ 不妊症におけるホスホジエステラーゼ阻害剤
EP1748984A1 (en) * 2004-05-12 2007-02-07 Pfizer Products Inc. Piperidine derivatives as nk1 and nk3 antagonists
CA2688161C (en) 2007-06-04 2020-10-20 Kunwar Shailubhai Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
CA2726917C (en) 2008-06-04 2018-06-26 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
JP2011528375A (ja) 2008-07-16 2011-11-17 シナジー ファーマシューティカルズ インコーポレイテッド 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
WO2012118972A2 (en) 2011-03-01 2012-09-07 Synegy Pharmaceuticals Inc. Process of preparing guanylate cyclase c agonists
AU2014218599C1 (en) 2013-02-25 2018-09-06 Bausch Health Ireland Limited Guanylate cyclase receptor agonists for use in colonic cleansing
EP2970384A1 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
CA2905435A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
CN105764916B (zh) 2013-06-05 2021-05-18 博士医疗爱尔兰有限公司 鸟苷酸环化酶c的超纯激动剂、制备和使用所述激动剂的方法
IL280864B2 (en) 2013-08-09 2024-03-01 Ardelyx Inc Compounds and methods for inhibiting phosphate transport
CN114340631A (zh) 2019-05-21 2022-04-12 阿德利克斯股份有限公司 用于降低患者的血清磷酸盐的组合

Also Published As

Publication number Publication date
AT326674B (de) 1975-12-29
DK134488B (da) 1976-11-15
ES391026A1 (es) 1974-04-01
CS167202B2 (cs) 1976-04-29
CS162753B2 (cs) 1975-07-15
FI52089C (fi) 1977-06-10
FR2100649B1 (cs) 1974-08-30
JPS5432799B1 (cs) 1979-10-16
SU423296A3 (ru) 1974-04-05
ATA412471A (de) 1975-03-15
GB1361441A (en) 1974-07-24
PL76913B1 (en) 1975-02-28
NL7106502A (cs) 1971-11-16
FR2100649A1 (cs) 1972-03-24
SE387640B (sv) 1976-09-13
DK134488C (cs) 1977-05-16
FI52089B (cs) 1977-02-28
DE2123328A1 (de) 1971-12-02

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