CA970377A - Benzonaphthyridine derivatives - Google Patents
Benzonaphthyridine derivativesInfo
- Publication number
- CA970377A CA970377A CA112,767A CA112767A CA970377A CA 970377 A CA970377 A CA 970377A CA 112767 A CA112767 A CA 112767A CA 970377 A CA970377 A CA 970377A
- Authority
- CA
- Canada
- Prior art keywords
- benzonaphthyridine derivatives
- benzonaphthyridine
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- BJVCSICIEDHBNI-UHFFFAOYSA-N benzo[b][1,8]naphthyridine Chemical class N1=CC=CC2=CC3=CC=CC=C3N=C21 BJVCSICIEDHBNI-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH708970A CH527822A (de) | 1970-05-13 | 1970-05-13 | Verfahren zur Herstellung neuer Benzonaphtyridin-Derivate |
| CH708670A CH527196A (de) | 1970-05-13 | 1970-05-13 | Verfahren zur Herstellung neuer Benzonaphthyridinderivate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA970377A true CA970377A (en) | 1975-07-01 |
Family
ID=25700728
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA112,767A Expired CA970377A (en) | 1970-05-13 | 1971-05-12 | Benzonaphthyridine derivatives |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS5432799B1 (cs) |
| AT (1) | AT326674B (cs) |
| CA (1) | CA970377A (cs) |
| CS (2) | CS167202B2 (cs) |
| DE (1) | DE2123328A1 (cs) |
| DK (1) | DK134488B (cs) |
| ES (1) | ES391026A1 (cs) |
| FI (1) | FI52089C (cs) |
| FR (1) | FR2100649B1 (cs) |
| GB (1) | GB1361441A (cs) |
| NL (1) | NL7106502A (cs) |
| PL (1) | PL76913B1 (cs) |
| SE (1) | SE387640B (cs) |
| SU (1) | SU423296A3 (cs) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3899494A (en) * | 1970-05-13 | 1975-08-12 | Sandoz Ltd | Substituted 6-phenyl benzo-naphthyridines |
| NL7314396A (cs) * | 1972-10-26 | 1974-05-01 | ||
| BE880455A (fr) * | 1979-01-22 | 1980-06-06 | Sandoz Sa | Compositions pharmaceutiques a base d'une benzo (c) (1,6) naphtyridine |
| ES2193539T3 (es) * | 1997-06-03 | 2003-11-01 | Altana Pharma Ag | Benzonaftiridinas. |
| NZ517166A (en) | 1999-08-21 | 2004-01-30 | Altana Pharma Ag | Synergistic combination of PDE inhibitors and beta 2 adrenoceptor agonists |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| EP1624893A2 (en) | 2003-04-01 | 2006-02-15 | Applied Research Systems ARS Holding N.V. | Inhibitors of phosphodiesterases in infertility |
| BRPI0510951A (pt) * | 2004-05-12 | 2007-11-20 | Pfizer Prod Inc | derivados de piperidina como antagonistas de nk1 e nk3 |
| AU2008261102B2 (en) | 2007-06-04 | 2013-11-28 | Bausch Health Ireland Limited | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| US8034782B2 (en) | 2008-07-16 | 2011-10-11 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| CA2930674A1 (en) | 2008-06-04 | 2009-12-10 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| EP2681236B1 (en) | 2011-03-01 | 2018-01-03 | Synergy Pharmaceuticals Inc. | Process of preparing guanylate cyclase c agonists |
| JP6499591B2 (ja) | 2013-02-25 | 2019-04-10 | シナジー ファーマシューティカルズ インコーポレイテッド | 結腸洗浄において用いるためのグアニル酸シクラーゼ受容体アゴニスト |
| AU2014235215A1 (en) | 2013-03-15 | 2015-10-01 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
| EP2968439A2 (en) | 2013-03-15 | 2016-01-20 | Synergy Pharmaceuticals Inc. | Compositions useful for the treatment of gastrointestinal disorders |
| CN113388007A (zh) | 2013-06-05 | 2021-09-14 | 博士医疗爱尔兰有限公司 | 鸟苷酸环化酶c的超纯激动剂、制备和使用所述激动剂的方法 |
| MX375926B (es) | 2013-08-09 | 2025-03-07 | Ardelyx Inc | Compuestos y metodos para inhibir el transporte de fosfato. |
| EP3972599B1 (en) | 2019-05-21 | 2025-10-22 | Ardelyx, Inc. | Combination for lowering serum phosphate in a patient |
-
1971
- 1971-05-10 GB GB1398471A patent/GB1361441A/en not_active Expired
- 1971-05-11 DE DE19712123328 patent/DE2123328A1/de not_active Ceased
- 1971-05-11 CS CS920771A patent/CS167202B2/cs unknown
- 1971-05-11 ES ES391026A patent/ES391026A1/es not_active Expired
- 1971-05-11 DK DK225771A patent/DK134488B/da unknown
- 1971-05-11 PL PL14807271A patent/PL76913B1/pl unknown
- 1971-05-11 FI FI129371A patent/FI52089C/fi active
- 1971-05-11 SU SU1656559A patent/SU423296A3/ru active
- 1971-05-11 CS CS341671A patent/CS162753B2/cs unknown
- 1971-05-12 NL NL7106502A patent/NL7106502A/xx not_active Application Discontinuation
- 1971-05-12 JP JP3189471A patent/JPS5432799B1/ja active Pending
- 1971-05-12 AT AT412471A patent/AT326674B/de not_active IP Right Cessation
- 1971-05-12 CA CA112,767A patent/CA970377A/en not_active Expired
- 1971-05-12 FR FR7117124A patent/FR2100649B1/fr not_active Expired
- 1971-05-12 SE SE613471A patent/SE387640B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CS167202B2 (cs) | 1976-04-29 |
| DE2123328A1 (de) | 1971-12-02 |
| SU423296A3 (ru) | 1974-04-05 |
| NL7106502A (cs) | 1971-11-16 |
| ATA412471A (de) | 1975-03-15 |
| DK134488B (da) | 1976-11-15 |
| FR2100649B1 (cs) | 1974-08-30 |
| GB1361441A (en) | 1974-07-24 |
| FR2100649A1 (cs) | 1972-03-24 |
| PL76913B1 (en) | 1975-02-28 |
| CS162753B2 (cs) | 1975-07-15 |
| FI52089C (fi) | 1977-06-10 |
| AT326674B (de) | 1975-12-29 |
| FI52089B (cs) | 1977-02-28 |
| JPS5432799B1 (cs) | 1979-10-16 |
| SE387640B (sv) | 1976-09-13 |
| DK134488C (cs) | 1977-05-16 |
| ES391026A1 (es) | 1974-04-01 |
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