GB1361441A - Benzonaphthyridine derivatives - Google Patents
Benzonaphthyridine derivativesInfo
- Publication number
- GB1361441A GB1361441A GB1398471A GB1398471A GB1361441A GB 1361441 A GB1361441 A GB 1361441A GB 1398471 A GB1398471 A GB 1398471A GB 1398471 A GB1398471 A GB 1398471A GB 1361441 A GB1361441 A GB 1361441A
- Authority
- GB
- United Kingdom
- Prior art keywords
- cis
- amino
- amido
- benzo
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH708670A CH527196A (de) | 1970-05-13 | 1970-05-13 | Verfahren zur Herstellung neuer Benzonaphthyridinderivate |
| CH708970A CH527822A (de) | 1970-05-13 | 1970-05-13 | Verfahren zur Herstellung neuer Benzonaphtyridin-Derivate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1361441A true GB1361441A (en) | 1974-07-24 |
Family
ID=25700728
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1398471A Expired GB1361441A (en) | 1970-05-13 | 1971-05-10 | Benzonaphthyridine derivatives |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS5432799B1 (cs) |
| AT (1) | AT326674B (cs) |
| CA (1) | CA970377A (cs) |
| CS (2) | CS162753B2 (cs) |
| DE (1) | DE2123328A1 (cs) |
| DK (1) | DK134488B (cs) |
| ES (1) | ES391026A1 (cs) |
| FI (1) | FI52089C (cs) |
| FR (1) | FR2100649B1 (cs) |
| GB (1) | GB1361441A (cs) |
| NL (1) | NL7106502A (cs) |
| PL (1) | PL76913B1 (cs) |
| SE (1) | SE387640B (cs) |
| SU (1) | SU423296A3 (cs) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3899494A (en) * | 1970-05-13 | 1975-08-12 | Sandoz Ltd | Substituted 6-phenyl benzo-naphthyridines |
| NL7314396A (cs) * | 1972-10-26 | 1974-05-01 | ||
| BE880455A (fr) * | 1979-01-22 | 1980-06-06 | Sandoz Sa | Compositions pharmaceutiques a base d'une benzo (c) (1,6) naphtyridine |
| US6384047B1 (en) | 1997-06-03 | 2002-05-07 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Benzonaphthyridine |
| BRPI0013478B8 (pt) | 1999-08-21 | 2016-12-27 | Altana Pharma Ag | medicamento compreendendo inibidor pde e uso de roflumilast |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| JP2006522151A (ja) | 2003-04-01 | 2006-09-28 | アプライド リサーチ システムズ エーアールエス ホールディング ナームロゼ フェンノートシャップ | 不妊症におけるホスホジエステラーゼ阻害剤 |
| EP1748984A1 (en) * | 2004-05-12 | 2007-02-07 | Pfizer Products Inc. | Piperidine derivatives as nk1 and nk3 antagonists |
| CA2688161C (en) | 2007-06-04 | 2020-10-20 | Kunwar Shailubhai | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| CA2726917C (en) | 2008-06-04 | 2018-06-26 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| JP2011528375A (ja) | 2008-07-16 | 2011-11-17 | シナジー ファーマシューティカルズ インコーポレイテッド | 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| WO2012118972A2 (en) | 2011-03-01 | 2012-09-07 | Synegy Pharmaceuticals Inc. | Process of preparing guanylate cyclase c agonists |
| AU2014218599C1 (en) | 2013-02-25 | 2018-09-06 | Bausch Health Ireland Limited | Guanylate cyclase receptor agonists for use in colonic cleansing |
| EP2970384A1 (en) | 2013-03-15 | 2016-01-20 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
| CA2905435A1 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Compositions useful for the treatment of gastrointestinal disorders |
| CN105764916B (zh) | 2013-06-05 | 2021-05-18 | 博士医疗爱尔兰有限公司 | 鸟苷酸环化酶c的超纯激动剂、制备和使用所述激动剂的方法 |
| IL280864B2 (en) | 2013-08-09 | 2024-03-01 | Ardelyx Inc | Compounds and methods for inhibiting phosphate transport |
| CN114340631A (zh) | 2019-05-21 | 2022-04-12 | 阿德利克斯股份有限公司 | 用于降低患者的血清磷酸盐的组合 |
-
1971
- 1971-05-10 GB GB1398471A patent/GB1361441A/en not_active Expired
- 1971-05-11 FI FI129371A patent/FI52089C/fi active
- 1971-05-11 PL PL14807271A patent/PL76913B1/pl unknown
- 1971-05-11 ES ES391026A patent/ES391026A1/es not_active Expired
- 1971-05-11 CS CS341671A patent/CS162753B2/cs unknown
- 1971-05-11 DE DE19712123328 patent/DE2123328A1/de not_active Ceased
- 1971-05-11 DK DK225771A patent/DK134488B/da unknown
- 1971-05-11 CS CS920771A patent/CS167202B2/cs unknown
- 1971-05-11 SU SU1656559A patent/SU423296A3/ru active
- 1971-05-12 JP JP3189471A patent/JPS5432799B1/ja active Pending
- 1971-05-12 AT AT412471A patent/AT326674B/de not_active IP Right Cessation
- 1971-05-12 FR FR7117124A patent/FR2100649B1/fr not_active Expired
- 1971-05-12 SE SE613471A patent/SE387640B/xx unknown
- 1971-05-12 NL NL7106502A patent/NL7106502A/xx not_active Application Discontinuation
- 1971-05-12 CA CA112,767A patent/CA970377A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AT326674B (de) | 1975-12-29 |
| DK134488B (da) | 1976-11-15 |
| ES391026A1 (es) | 1974-04-01 |
| CS167202B2 (cs) | 1976-04-29 |
| CS162753B2 (cs) | 1975-07-15 |
| FI52089C (fi) | 1977-06-10 |
| FR2100649B1 (cs) | 1974-08-30 |
| JPS5432799B1 (cs) | 1979-10-16 |
| CA970377A (en) | 1975-07-01 |
| SU423296A3 (ru) | 1974-04-05 |
| ATA412471A (de) | 1975-03-15 |
| PL76913B1 (en) | 1975-02-28 |
| NL7106502A (cs) | 1971-11-16 |
| FR2100649A1 (cs) | 1972-03-24 |
| SE387640B (sv) | 1976-09-13 |
| DK134488C (cs) | 1977-05-16 |
| FI52089B (cs) | 1977-02-28 |
| DE2123328A1 (de) | 1971-12-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| 429A | Application made for amendment of specification (sect. 29/1949) | ||
| 429H | Application (made) for amendment of specification now open to opposition (sect. 29/1949) | ||
| 429D | Case decided by the comptroller ** specification amended (sect. 29/1949) | ||
| SPA | Amended specification published | ||
| PCNP | Patent ceased through non-payment of renewal fee |