FR2100649A1 - - Google Patents

Info

Publication number
FR2100649A1
FR2100649A1 FR7117124A FR7117124A FR2100649A1 FR 2100649 A1 FR2100649 A1 FR 2100649A1 FR 7117124 A FR7117124 A FR 7117124A FR 7117124 A FR7117124 A FR 7117124A FR 2100649 A1 FR2100649 A1 FR 2100649A1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7117124A
Other languages
French (fr)
Other versions
FR2100649B1 (cs
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH708670A external-priority patent/CH527196A/de
Priority claimed from CH708970A external-priority patent/CH527822A/de
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of FR2100649A1 publication Critical patent/FR2100649A1/fr
Application granted granted Critical
Publication of FR2100649B1 publication Critical patent/FR2100649B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR7117124A 1970-05-13 1971-05-12 Expired FR2100649B1 (cs)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH708670A CH527196A (de) 1970-05-13 1970-05-13 Verfahren zur Herstellung neuer Benzonaphthyridinderivate
CH708970A CH527822A (de) 1970-05-13 1970-05-13 Verfahren zur Herstellung neuer Benzonaphtyridin-Derivate

Publications (2)

Publication Number Publication Date
FR2100649A1 true FR2100649A1 (cs) 1972-03-24
FR2100649B1 FR2100649B1 (cs) 1974-08-30

Family

ID=25700728

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7117124A Expired FR2100649B1 (cs) 1970-05-13 1971-05-12

Country Status (14)

Country Link
JP (1) JPS5432799B1 (cs)
AT (1) AT326674B (cs)
CA (1) CA970377A (cs)
CS (2) CS162753B2 (cs)
DE (1) DE2123328A1 (cs)
DK (1) DK134488B (cs)
ES (1) ES391026A1 (cs)
FI (1) FI52089C (cs)
FR (1) FR2100649B1 (cs)
GB (1) GB1361441A (cs)
NL (1) NL7106502A (cs)
PL (1) PL76913B1 (cs)
SE (1) SE387640B (cs)
SU (1) SU423296A3 (cs)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2204418A1 (en) * 1972-10-26 1974-05-24 Sandoz Sa 8,9-Dimethoxy-6-acylaminophenyl-2-methyl benzo(c) (1,6)-naphthyridines - used to inhibit aggregation of blood platelets
FR2446636A1 (fr) * 1979-01-22 1980-08-14 Sandoz Sa Nouvelles compositions pharmaceutiques a base d'une benzo(c) (1,6)naphtyridine

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3899494A (en) * 1970-05-13 1975-08-12 Sandoz Ltd Substituted 6-phenyl benzo-naphthyridines
US6384047B1 (en) 1997-06-03 2002-05-07 Byk Gulden Lomberg Chemische Fabrik Gmbh Benzonaphthyridine
BRPI0013478B8 (pt) 1999-08-21 2016-12-27 Altana Pharma Ag medicamento compreendendo inibidor pde e uso de roflumilast
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
JP2006522151A (ja) 2003-04-01 2006-09-28 アプライド リサーチ システムズ エーアールエス ホールディング ナームロゼ フェンノートシャップ 不妊症におけるホスホジエステラーゼ阻害剤
EP1748984A1 (en) * 2004-05-12 2007-02-07 Pfizer Products Inc. Piperidine derivatives as nk1 and nk3 antagonists
CA2688161C (en) 2007-06-04 2020-10-20 Kunwar Shailubhai Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
CA2726917C (en) 2008-06-04 2018-06-26 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
JP2011528375A (ja) 2008-07-16 2011-11-17 シナジー ファーマシューティカルズ インコーポレイテッド 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
WO2012118972A2 (en) 2011-03-01 2012-09-07 Synegy Pharmaceuticals Inc. Process of preparing guanylate cyclase c agonists
AU2014218599C1 (en) 2013-02-25 2018-09-06 Bausch Health Ireland Limited Guanylate cyclase receptor agonists for use in colonic cleansing
EP2970384A1 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
CA2905435A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
CN105764916B (zh) 2013-06-05 2021-05-18 博士医疗爱尔兰有限公司 鸟苷酸环化酶c的超纯激动剂、制备和使用所述激动剂的方法
IL280864B2 (en) 2013-08-09 2024-03-01 Ardelyx Inc Compounds and methods for inhibiting phosphate transport
CN114340631A (zh) 2019-05-21 2022-04-12 阿德利克斯股份有限公司 用于降低患者的血清磷酸盐的组合

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2204418A1 (en) * 1972-10-26 1974-05-24 Sandoz Sa 8,9-Dimethoxy-6-acylaminophenyl-2-methyl benzo(c) (1,6)-naphthyridines - used to inhibit aggregation of blood platelets
FR2446636A1 (fr) * 1979-01-22 1980-08-14 Sandoz Sa Nouvelles compositions pharmaceutiques a base d'une benzo(c) (1,6)naphtyridine

Also Published As

Publication number Publication date
AT326674B (de) 1975-12-29
DK134488B (da) 1976-11-15
ES391026A1 (es) 1974-04-01
CS167202B2 (cs) 1976-04-29
CS162753B2 (cs) 1975-07-15
FI52089C (fi) 1977-06-10
FR2100649B1 (cs) 1974-08-30
JPS5432799B1 (cs) 1979-10-16
CA970377A (en) 1975-07-01
SU423296A3 (ru) 1974-04-05
ATA412471A (de) 1975-03-15
GB1361441A (en) 1974-07-24
PL76913B1 (en) 1975-02-28
NL7106502A (cs) 1971-11-16
SE387640B (sv) 1976-09-13
DK134488C (cs) 1977-05-16
FI52089B (cs) 1977-02-28
DE2123328A1 (de) 1971-12-02

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Legal Events

Date Code Title Description
ST Notification of lapse