FI3746467T3 - Muutetut lipidoidut relaksiinin b-ketjun peptidit ja niiden terapeuttinen käyttö - Google Patents
Muutetut lipidoidut relaksiinin b-ketjun peptidit ja niiden terapeuttinen käyttöInfo
- Publication number
- FI3746467T3 FI3746467T3 FIEP19702593.5T FI19702593T FI3746467T3 FI 3746467 T3 FI3746467 T3 FI 3746467T3 FI 19702593 T FI19702593 T FI 19702593T FI 3746467 T3 FI3746467 T3 FI 3746467T3
- Authority
- FI
- Finland
- Prior art keywords
- group
- denotes
- amino acid
- ttds
- palm
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/64—Relaxins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2221—Relaxins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18305094 | 2018-01-31 | ||
| PCT/EP2019/052298 WO2019149782A1 (en) | 2018-01-31 | 2019-01-30 | Modified lipidated relaxin b chain peptides and their therapeutic use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FI3746467T3 true FI3746467T3 (fi) | 2026-01-16 |
Family
ID=61223862
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FIEP19702593.5T FI3746467T3 (fi) | 2018-01-31 | 2019-01-30 | Muutetut lipidoidut relaksiinin b-ketjun peptidit ja niiden terapeuttinen käyttö |
Country Status (29)
| Country | Link |
|---|---|
| US (3) | US10961295B2 (https=) |
| EP (1) | EP3746467B1 (https=) |
| JP (1) | JP7295871B2 (https=) |
| KR (1) | KR102755938B1 (https=) |
| CN (1) | CN111770934B (https=) |
| AR (1) | AR114325A1 (https=) |
| AU (1) | AU2019214358B2 (https=) |
| BR (1) | BR112020014834A2 (https=) |
| CA (1) | CA3089657A1 (https=) |
| CO (1) | CO2020008308A2 (https=) |
| DK (1) | DK3746467T3 (https=) |
| ES (1) | ES3058633T3 (https=) |
| FI (1) | FI3746467T3 (https=) |
| HR (1) | HRP20260016T1 (https=) |
| IL (2) | IL316406A (https=) |
| LT (1) | LT3746467T (https=) |
| MA (1) | MA52994A (https=) |
| MX (1) | MX2020008096A (https=) |
| MY (1) | MY199821A (https=) |
| NZ (1) | NZ766762A (https=) |
| PH (1) | PH12020551118A1 (https=) |
| PL (1) | PL3746467T3 (https=) |
| PT (1) | PT3746467T (https=) |
| RS (1) | RS67606B1 (https=) |
| SG (1) | SG11202006903WA (https=) |
| SI (1) | SI3746467T1 (https=) |
| TW (1) | TWI763972B (https=) |
| UY (1) | UY38069A (https=) |
| WO (1) | WO2019149782A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110637027B (zh) | 2017-02-08 | 2024-08-30 | 百时美施贵宝公司 | 包含药代动力学增强子的修饰的松弛素多肽及其用途 |
| WO2019149781A1 (en) * | 2018-01-31 | 2019-08-08 | Sanofi | Modified lipidated relaxin b chain peptides and their therapeutic use |
| MA52994A (fr) | 2018-01-31 | 2021-05-05 | Sanofi Sa | Peptides à chaîne b de relaxine lipidés modifiés et leur utilisation thérapeutique |
| WO2022159395A1 (en) | 2021-01-20 | 2022-07-28 | Viking Therapeutics, Inc. | Compositions and methods for the treatment of metabolic and liver disorders |
| US20240400638A1 (en) * | 2021-08-23 | 2024-12-05 | Guido MAGNI | Combination of relaxin and vasopressin analogues for treatment of renal disorders or conditions |
| MX2024003236A (es) | 2021-09-15 | 2024-06-19 | Viking Therapeutics Inc | Composiciones y metodos para el tratamiento de trastornos metabolicos y hepaticos. |
| WO2023086913A2 (en) | 2021-11-11 | 2023-05-19 | Tectonic Therapeutic, Inc. | Relaxin-2 fusion protein analogs and methods of using same |
| CN115998842B (zh) * | 2022-09-02 | 2025-08-26 | 郑州大学第一附属医院 | 一种逆转肝星形细胞激活的仿生纳米药物及其应用 |
| KR20260035823A (ko) | 2023-05-18 | 2026-03-13 | 테크토닉 오퍼레이팅 컴퍼니 인코포레이티드 | 렐락신-2 융합 단백질 유사체 및 이를 사용하는 방법 |
| KR20250054870A (ko) * | 2023-10-16 | 2025-04-24 | (주)케어젠 | 피부 상태 개선 활성을 갖는 펩타이드 및 이의 용도 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0923283A2 (pt) * | 2008-12-05 | 2017-06-06 | Angiochem Inc | conjugados terapêuticos de peptídeo e usos dos mesmos |
| EP2460527A1 (en) * | 2010-01-21 | 2012-06-06 | Sanofi | Pharmaceutical composition for treating a metabolic syndrome |
| EP2524915A1 (en) * | 2011-05-20 | 2012-11-21 | Sanofi | 2-Amino-3-(imidazol-2-yl)-pyridin-4-one derivatives and their use as VEGF receptor kinase inhibitors |
| TW201315739A (zh) * | 2011-07-01 | 2013-04-16 | 拜耳智慧財產有限公司 | 鬆弛素（ｒｅｌａｘｉｎ）融合多肽類及其用途 |
| EP2726502A1 (en) * | 2011-07-01 | 2014-05-07 | Bayer Intellectual Property GmbH | Relaxin fusion polypeptides and uses thereof |
| JP6276690B2 (ja) * | 2011-08-04 | 2018-02-07 | ファリス バイオテック ゲーエムベーハー | ヒトリラキシン−２を調製する方法 |
| US20160152679A1 (en) | 2012-05-24 | 2016-06-02 | Angion Biomedica Corp. | Relaxin-like compounds and uses thereof |
| CN105792851B (zh) * | 2013-09-13 | 2023-10-10 | 斯克利普斯研究所 | 修饰的治疗剂及其组合物 |
| CA2945838C (en) * | 2014-04-17 | 2022-08-16 | The Florey Institute Of Neuroscience And Mental Health | Modified relaxin b chain peptides |
| EP3838285A1 (en) * | 2014-04-22 | 2021-06-23 | TXP Pharma GmbH | Peptide analogues with branched amino acid probe(s) |
| CN110637027B (zh) * | 2017-02-08 | 2024-08-30 | 百时美施贵宝公司 | 包含药代动力学增强子的修饰的松弛素多肽及其用途 |
| MA52994A (fr) | 2018-01-31 | 2021-05-05 | Sanofi Sa | Peptides à chaîne b de relaxine lipidés modifiés et leur utilisation thérapeutique |
| TW201934572A (zh) * | 2018-01-31 | 2019-09-01 | 法商賽諾菲公司 | 經修飾之鬆弛素ｂ鏈胜肽及其治療用途 |
| WO2019149781A1 (en) * | 2018-01-31 | 2019-08-08 | Sanofi | Modified lipidated relaxin b chain peptides and their therapeutic use |
| TWI844709B (zh) * | 2019-07-31 | 2024-06-11 | 美商美國禮來大藥廠 | 鬆弛素(relaxin)類似物及其使用方法 |
| US20240400638A1 (en) * | 2021-08-23 | 2024-12-05 | Guido MAGNI | Combination of relaxin and vasopressin analogues for treatment of renal disorders or conditions |
-
2019
- 2019-01-30 MA MA052994A patent/MA52994A/fr unknown
- 2019-01-30 WO PCT/EP2019/052298 patent/WO2019149782A1/en not_active Ceased
- 2019-01-30 ES ES19702593T patent/ES3058633T3/es active Active
- 2019-01-30 MX MX2020008096A patent/MX2020008096A/es unknown
- 2019-01-30 PL PL19702593.5T patent/PL3746467T3/pl unknown
- 2019-01-30 FI FIEP19702593.5T patent/FI3746467T3/fi active
- 2019-01-30 CN CN201980015588.9A patent/CN111770934B/zh active Active
- 2019-01-30 HR HRP20260016TT patent/HRP20260016T1/hr unknown
- 2019-01-30 JP JP2020541689A patent/JP7295871B2/ja active Active
- 2019-01-30 NZ NZ766762A patent/NZ766762A/en unknown
- 2019-01-30 AU AU2019214358A patent/AU2019214358B2/en active Active
- 2019-01-30 RS RS20260005A patent/RS67606B1/sr unknown
- 2019-01-30 LT LTEPPCT/EP2019/052298T patent/LT3746467T/lt unknown
- 2019-01-30 EP EP19702593.5A patent/EP3746467B1/en active Active
- 2019-01-30 SI SI201931009T patent/SI3746467T1/sl unknown
- 2019-01-30 SG SG11202006903WA patent/SG11202006903WA/en unknown
- 2019-01-30 PT PT197025935T patent/PT3746467T/pt unknown
- 2019-01-30 IL IL316406A patent/IL316406A/en unknown
- 2019-01-30 DK DK19702593.5T patent/DK3746467T3/da active
- 2019-01-30 MY MYPI2020003535A patent/MY199821A/en unknown
- 2019-01-30 BR BR112020014834-2A patent/BR112020014834A2/pt unknown
- 2019-01-30 KR KR1020207020681A patent/KR102755938B1/ko active Active
- 2019-01-30 CA CA3089657A patent/CA3089657A1/en active Pending
- 2019-01-30 IL IL276170A patent/IL276170B2/en unknown
- 2019-01-31 US US16/264,643 patent/US10961295B2/en active Active
- 2019-01-31 TW TW108103457A patent/TWI763972B/zh active
- 2019-01-31 AR ARP190100222A patent/AR114325A1/es unknown
- 2019-01-31 UY UY38069A patent/UY38069A/es not_active Application Discontinuation
-
2020
- 2020-07-06 CO CONC2020/0008308A patent/CO2020008308A2/es unknown
- 2020-07-22 PH PH12020551118A patent/PH12020551118A1/en unknown
- 2020-10-30 US US17/086,183 patent/US11725036B2/en active Active
-
2023
- 2023-06-26 US US18/341,320 patent/US20240218042A1/en active Pending
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