JP2022518695A5 - - Google Patents

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Publication number
JP2022518695A5
JP2022518695A5 JP2021540809A JP2021540809A JP2022518695A5 JP 2022518695 A5 JP2022518695 A5 JP 2022518695A5 JP 2021540809 A JP2021540809 A JP 2021540809A JP 2021540809 A JP2021540809 A JP 2021540809A JP 2022518695 A5 JP2022518695 A5 JP 2022518695A5
Authority
JP
Japan
Prior art keywords
sequence
referred
peptide ligand
ligand according
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021540809A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022518695A (ja
Filing date
Publication date
Priority claimed from GBGB1900525.5A external-priority patent/GB201900525D0/en
Application filed filed Critical
Publication of JP2022518695A publication Critical patent/JP2022518695A/ja
Publication of JP2022518695A5 publication Critical patent/JP2022518695A5/ja
Pending legal-status Critical Current

Links

JP2021540809A 2019-01-15 2020-01-15 Caixに特異的な二環式ペプチドリガンド Pending JP2022518695A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1900525.5 2019-01-15
GBGB1900525.5A GB201900525D0 (en) 2019-01-15 2019-01-15 Bicyclic peptide ligands specific for caix
PCT/GB2020/050069 WO2020148525A1 (en) 2019-01-15 2020-01-15 Bicyclic peptide ligands specific for caix

Publications (2)

Publication Number Publication Date
JP2022518695A JP2022518695A (ja) 2022-03-16
JP2022518695A5 true JP2022518695A5 (https=) 2023-01-25

Family

ID=65528179

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021540809A Pending JP2022518695A (ja) 2019-01-15 2020-01-15 Caixに特異的な二環式ペプチドリガンド

Country Status (6)

Country Link
US (1) US20220088118A1 (https=)
EP (1) EP3911665A1 (https=)
JP (1) JP2022518695A (https=)
CN (1) CN113383007A (https=)
GB (1) GB201900525D0 (https=)
WO (1) WO2020148525A1 (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107148425B (zh) 2014-10-29 2021-08-03 拜斯科阿迪有限公司 对mt1-mmp特异性的双环肽配体
EP3645549A1 (en) 2017-06-26 2020-05-06 BicycleRD Limited Bicyclic peptide ligands with detectable moieties and uses thereof
JP7670481B2 (ja) 2017-08-04 2025-04-30 バイスクルテクス・リミテッド Cd137に対して特異的な二環式ペプチドリガンド
CN111902429A (zh) 2018-02-23 2020-11-06 拜斯科技术开发有限公司 多聚体双环肽配体
IL279489B2 (en) 2018-06-22 2025-10-01 Bicycletx Ltd Bicyclic peptide ligands specific for nectin-4, a drug conjugate containing the peptide ligands and a pharmaceutical composition containing the drug conjugate
GB201820288D0 (en) 2018-12-13 2019-01-30 Bicycle Tx Ltd Bicycle peptide ligaands specific for MT1-MMP
GB201820295D0 (en) 2018-12-13 2019-01-30 Bicyclerd Ltd Bicyclic peptide ligands specific for MT1-MMP
GB201820325D0 (en) 2018-12-13 2019-01-30 Bicyclerd Ltd Bicyclic peptide ligands specific for psma
US12492224B2 (en) 2018-12-21 2025-12-09 Bicycletx Limited Bicyclic peptide ligands specific for PD-L1
WO2020128527A1 (en) 2018-12-21 2020-06-25 Bicyclerd Limited Bicyclic peptide ligands specific for pd-l1
GB201900529D0 (en) 2019-01-15 2019-03-06 Bicycletx Ltd Bicyclic peptide ligands specific for CD38
TWI860386B (zh) 2019-07-30 2024-11-01 英商拜西可泰克斯有限公司 異質雙環肽複合物
AU2021322934A1 (en) 2020-08-03 2023-03-30 Bicycletx Limited Peptide-based linkers
TW202340226A (zh) * 2021-12-17 2023-10-16 德商3B製藥有限公司 碳酸酐酶ix配位體
CA3243979A1 (en) * 2022-02-11 2025-04-30 C-Biomex Co., Ltd. Peptide ligand targeting carbonic anhydrase IX, peptide construction comprising it, and associated uses
WO2025023747A1 (ko) * 2023-07-25 2025-01-30 (주)씨바이오멕스 탄산탈수소효소 ⅸ를 표적으로 하는 펩타이드 구조체 및 이들의 용도
CN120943901A (zh) * 2025-05-29 2025-11-14 北京肿瘤医院(北京大学肿瘤医院) 经修饰的caix靶向环肽、核素标记物及其在肿瘤诊疗方面的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2653545A1 (en) 2008-02-05 2013-10-23 Bicycle Therapeutics Limited Methods and compositions
CN107148425B (zh) 2014-10-29 2021-08-03 拜斯科阿迪有限公司 对mt1-mmp特异性的双环肽配体
US10857196B2 (en) * 2017-04-27 2020-12-08 Bicycletx Limited Bicyclic peptide ligands and uses thereof
EP3645549A1 (en) * 2017-06-26 2020-05-06 BicycleRD Limited Bicyclic peptide ligands with detectable moieties and uses thereof

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