JP2022517442A5 - - Google Patents
Info
- Publication number
- JP2022517442A5 JP2022517442A5 JP2021563433A JP2021563433A JP2022517442A5 JP 2022517442 A5 JP2022517442 A5 JP 2022517442A5 JP 2021563433 A JP2021563433 A JP 2021563433A JP 2021563433 A JP2021563433 A JP 2021563433A JP 2022517442 A5 JP2022517442 A5 JP 2022517442A5
- Authority
- JP
- Japan
- Prior art keywords
- sequence
- referred
- peptide ligand
- sar
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1900526.3A GB201900526D0 (en) | 2019-01-15 | 2019-01-15 | Bicyclic peptide ligands specific for caix |
| GB1900526.3 | 2019-01-15 | ||
| PCT/GB2020/050070 WO2020148526A1 (en) | 2019-01-15 | 2020-01-15 | Bicyclic peptide ligands specific for caix |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022517442A JP2022517442A (ja) | 2022-03-08 |
| JP2022517442A5 true JP2022517442A5 (https=) | 2023-01-25 |
Family
ID=65528170
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021563433A Pending JP2022517442A (ja) | 2019-01-15 | 2020-01-15 | Ｃａｉｘに特異的な二環式ペプチドリガンド |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20220133732A1 (https=) |
| EP (1) | EP3911743A1 (https=) |
| JP (1) | JP2022517442A (https=) |
| CN (1) | CN113383074A (https=) |
| GB (1) | GB201900526D0 (https=) |
| WO (1) | WO2020148526A1 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107148425B (zh) | 2014-10-29 | 2021-08-03 | 拜斯科阿迪有限公司 | 对mt1-mmp特异性的双环肽配体 |
| EP3645549A1 (en) | 2017-06-26 | 2020-05-06 | BicycleRD Limited | Bicyclic peptide ligands with detectable moieties and uses thereof |
| JP7670481B2 (ja) | 2017-08-04 | 2025-04-30 | バイスクルテクス・リミテッド | Ｃｄ１３７に対して特異的な二環式ペプチドリガンド |
| CN111902429A (zh) | 2018-02-23 | 2020-11-06 | 拜斯科技术开发有限公司 | 多聚体双环肽配体 |
| IL279489B2 (en) | 2018-06-22 | 2025-10-01 | Bicycletx Ltd | Bicyclic peptide ligands specific for nectin-4, a drug conjugate containing the peptide ligands and a pharmaceutical composition containing the drug conjugate |
| GB201820288D0 (en) | 2018-12-13 | 2019-01-30 | Bicycle Tx Ltd | Bicycle peptide ligaands specific for MT1-MMP |
| GB201820295D0 (en) | 2018-12-13 | 2019-01-30 | Bicyclerd Ltd | Bicyclic peptide ligands specific for MT1-MMP |
| GB201820325D0 (en) | 2018-12-13 | 2019-01-30 | Bicyclerd Ltd | Bicyclic peptide ligands specific for psma |
| US12492224B2 (en) | 2018-12-21 | 2025-12-09 | Bicycletx Limited | Bicyclic peptide ligands specific for PD-L1 |
| WO2020128527A1 (en) | 2018-12-21 | 2020-06-25 | Bicyclerd Limited | Bicyclic peptide ligands specific for pd-l1 |
| GB201900529D0 (en) | 2019-01-15 | 2019-03-06 | Bicycletx Ltd | Bicyclic peptide ligands specific for CD38 |
| TWI860386B (zh) | 2019-07-30 | 2024-11-01 | 英商拜西可泰克斯有限公司 | 異質雙環肽複合物 |
| AU2021322934A1 (en) | 2020-08-03 | 2023-03-30 | Bicycletx Limited | Peptide-based linkers |
| TW202340226A (zh) | 2021-12-17 | 2023-10-16 | 德商３Ｂ製藥有限公司 | 碳酸酐酶ix配位體 |
| CA3243979A1 (en) * | 2022-02-11 | 2025-04-30 | C-Biomex Co., Ltd. | Peptide ligand targeting carbonic anhydrase IX, peptide construction comprising it, and associated uses |
| WO2024041535A1 (zh) * | 2022-08-22 | 2024-02-29 | 赣州和美药业股份有限公司 | 纳米组合物及其制备方法和用途 |
| CN120943901A (zh) * | 2025-05-29 | 2025-11-14 | 北京肿瘤医院(北京大学肿瘤医院) | 经修饰的caix靶向环肽、核素标记物及其在肿瘤诊疗方面的应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1452868A2 (en) | 2003-02-27 | 2004-09-01 | Pepscan Systems B.V. | Method for selecting a candidate drug compound |
| WO2006078161A1 (en) | 2005-01-24 | 2006-07-27 | Pepscan Systems B.V. | Binding compounds, immunogenic compounds and peptidomimetics |
| EP2653545A1 (en) | 2008-02-05 | 2013-10-23 | Bicycle Therapeutics Limited | Methods and compositions |
| CN107148425B (zh) | 2014-10-29 | 2021-08-03 | 拜斯科阿迪有限公司 | 对mt1-mmp特异性的双环肽配体 |
| GB201607827D0 (en) * | 2016-05-04 | 2016-06-15 | Bicycle Therapeutics Ltd | Bicyclic peptide-toxin conjugates specific for MT1-MMP |
| US10857196B2 (en) * | 2017-04-27 | 2020-12-08 | Bicycletx Limited | Bicyclic peptide ligands and uses thereof |
| EP3645549A1 (en) * | 2017-06-26 | 2020-05-06 | BicycleRD Limited | Bicyclic peptide ligands with detectable moieties and uses thereof |
-
2019
- 2019-01-15 GB GBGB1900526.3A patent/GB201900526D0/en not_active Ceased
-
2020
- 2020-01-15 EP EP20701119.8A patent/EP3911743A1/en not_active Withdrawn
- 2020-01-15 US US17/422,933 patent/US20220133732A1/en not_active Abandoned
- 2020-01-15 WO PCT/GB2020/050070 patent/WO2020148526A1/en not_active Ceased
- 2020-01-15 CN CN202080009486.9A patent/CN113383074A/zh active Pending
- 2020-01-15 JP JP2021563433A patent/JP2022517442A/ja active Pending
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