JP2022552839A5 - - Google Patents
Info
- Publication number
- JP2022552839A5 JP2022552839A5 JP2022522669A JP2022522669A JP2022552839A5 JP 2022552839 A5 JP2022552839 A5 JP 2022552839A5 JP 2022522669 A JP2022522669 A JP 2022522669A JP 2022522669 A JP2022522669 A JP 2022522669A JP 2022552839 A5 JP2022552839 A5 JP 2022552839A5
- Authority
- JP
- Japan
- Prior art keywords
- drug conjugate
- conjugate according
- peptide
- specific
- peptide ligands
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1914872.5 | 2019-10-15 | ||
| GB201914872A GB201914872D0 (en) | 2019-10-15 | 2019-10-15 | Bicyclic peptide ligand drug conjugates |
| PCT/GB2020/052590 WO2021074622A1 (en) | 2019-10-15 | 2020-10-15 | Bicyclic peptide ligand drug conjugates |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022552839A JP2022552839A (ja) | 2022-12-20 |
| JP2022552839A5 true JP2022552839A5 (https=) | 2023-10-19 |
Family
ID=68619460
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022522669A Pending JP2022552839A (ja) | 2019-10-15 | 2020-10-15 | 二環式ペプチドリガンド薬物コンジュゲート |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20240173422A1 (https=) |
| EP (1) | EP4045089A1 (https=) |
| JP (1) | JP2022552839A (https=) |
| KR (1) | KR20220088416A (https=) |
| CN (1) | CN114901317A (https=) |
| AU (1) | AU2020367325A1 (https=) |
| BR (1) | BR112022007099A2 (https=) |
| CA (1) | CA3154672A1 (https=) |
| GB (1) | GB201914872D0 (https=) |
| IL (1) | IL292113A (https=) |
| MX (1) | MX2022004572A (https=) |
| WO (1) | WO2021074622A1 (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107148425B (zh) | 2014-10-29 | 2021-08-03 | 拜斯科阿迪有限公司 | 对mt1-mmp特异性的双环肽配体 |
| EP3645549A1 (en) | 2017-06-26 | 2020-05-06 | BicycleRD Limited | Bicyclic peptide ligands with detectable moieties and uses thereof |
| JP7670481B2 (ja) | 2017-08-04 | 2025-04-30 | バイスクルテクス・リミテッド | Ｃｄ１３７に対して特異的な二環式ペプチドリガンド |
| CN111902429A (zh) | 2018-02-23 | 2020-11-06 | 拜斯科技术开发有限公司 | 多聚体双环肽配体 |
| IL279489B2 (en) | 2018-06-22 | 2025-10-01 | Bicycletx Ltd | Bicyclic peptide ligands specific for nectin-4, a drug conjugate containing the peptide ligands and a pharmaceutical composition containing the drug conjugate |
| GB201820295D0 (en) | 2018-12-13 | 2019-01-30 | Bicyclerd Ltd | Bicyclic peptide ligands specific for MT1-MMP |
| GB201820325D0 (en) | 2018-12-13 | 2019-01-30 | Bicyclerd Ltd | Bicyclic peptide ligands specific for psma |
| GB201820288D0 (en) | 2018-12-13 | 2019-01-30 | Bicycle Tx Ltd | Bicycle peptide ligaands specific for MT1-MMP |
| US12492224B2 (en) | 2018-12-21 | 2025-12-09 | Bicycletx Limited | Bicyclic peptide ligands specific for PD-L1 |
| WO2020128527A1 (en) | 2018-12-21 | 2020-06-25 | Bicyclerd Limited | Bicyclic peptide ligands specific for pd-l1 |
| GB201900529D0 (en) | 2019-01-15 | 2019-03-06 | Bicycletx Ltd | Bicyclic peptide ligands specific for CD38 |
| TWI860386B (zh) | 2019-07-30 | 2024-11-01 | 英商拜西可泰克斯有限公司 | 異質雙環肽複合物 |
| AU2021322934A1 (en) | 2020-08-03 | 2023-03-30 | Bicycletx Limited | Peptide-based linkers |
| GB202016331D0 (en) * | 2020-10-15 | 2020-12-02 | Bicyclerd Ltd | Bicyclic peptide ligand drug conjugates |
| WO2022253051A1 (zh) * | 2021-06-01 | 2022-12-08 | 南京明德新药研发有限公司 | 多肽偶联药物及其应用 |
| MX2024003876A (es) | 2021-09-29 | 2024-04-19 | Conjustar Zhuhai Biologics Co Ltd | Conjugado farmaco-polipeptido triciclico y sus aplicaciones. |
| GB202114279D0 (en) * | 2021-10-06 | 2021-11-17 | Bicycletx Ltd | Bicyclic peptide ligand drug conjugates |
| WO2023066314A1 (zh) * | 2021-10-19 | 2023-04-27 | 海思科医药集团股份有限公司 | Nectin-4的双环肽配体及其用途 |
| CN116768978A (zh) * | 2022-03-11 | 2023-09-19 | 上海智肽生物科技有限公司 | Nectin-4靶向肽化合物及其药物偶联物 |
| CN117003830A (zh) * | 2023-08-04 | 2023-11-07 | 湖南中晟全肽生化有限公司 | 靶向Nectin-4的多肽及其用途 |
| CN119701000A (zh) * | 2024-12-25 | 2025-03-28 | 中国人民解放军空军军医大学 | 一类多肽偶联药物及其制备方法和应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1452868A2 (en) | 2003-02-27 | 2004-09-01 | Pepscan Systems B.V. | Method for selecting a candidate drug compound |
| WO2006078161A1 (en) | 2005-01-24 | 2006-07-27 | Pepscan Systems B.V. | Binding compounds, immunogenic compounds and peptidomimetics |
| EP2653545A1 (en) | 2008-02-05 | 2013-10-23 | Bicycle Therapeutics Limited | Methods and compositions |
| CN107148425B (zh) | 2014-10-29 | 2021-08-03 | 拜斯科阿迪有限公司 | 对mt1-mmp特异性的双环肽配体 |
| CN111902429A (zh) * | 2018-02-23 | 2020-11-06 | 拜斯科技术开发有限公司 | 多聚体双环肽配体 |
| EP3774851A1 (en) * | 2018-04-04 | 2021-02-17 | BicycleTX Limited | Heterotandem bicyclic peptide complexes |
| IL279489B2 (en) * | 2018-06-22 | 2025-10-01 | Bicycletx Ltd | Bicyclic peptide ligands specific for nectin-4, a drug conjugate containing the peptide ligands and a pharmaceutical composition containing the drug conjugate |
-
2019
- 2019-10-15 GB GB201914872A patent/GB201914872D0/en not_active Ceased
-
2020
- 2020-10-15 US US17/769,668 patent/US20240173422A1/en active Pending
- 2020-10-15 CA CA3154672A patent/CA3154672A1/en active Pending
- 2020-10-15 CN CN202080071881.XA patent/CN114901317A/zh active Pending
- 2020-10-15 BR BR112022007099A patent/BR112022007099A2/pt not_active Application Discontinuation
- 2020-10-15 JP JP2022522669A patent/JP2022552839A/ja active Pending
- 2020-10-15 MX MX2022004572A patent/MX2022004572A/es unknown
- 2020-10-15 WO PCT/GB2020/052590 patent/WO2021074622A1/en not_active Ceased
- 2020-10-15 KR KR1020227011804A patent/KR20220088416A/ko not_active Withdrawn
- 2020-10-15 AU AU2020367325A patent/AU2020367325A1/en not_active Abandoned
- 2020-10-15 EP EP20796896.7A patent/EP4045089A1/en not_active Withdrawn
-
2022
- 2022-04-10 IL IL292113A patent/IL292113A/en unknown
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