JP2022515721A5 - - Google Patents
Info
- Publication number
- JP2022515721A5 JP2022515721A5 JP2021534207A JP2021534207A JP2022515721A5 JP 2022515721 A5 JP2022515721 A5 JP 2022515721A5 JP 2021534207 A JP2021534207 A JP 2021534207A JP 2021534207 A JP2021534207 A JP 2021534207A JP 2022515721 A5 JP2022515721 A5 JP 2022515721A5
- Authority
- JP
- Japan
- Prior art keywords
- peptide ligand
- ligand according
- sequence
- fapα
- cysteine residues
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1820320.8 | 2018-12-13 | ||
| GBGB1820320.8A GB201820320D0 (en) | 2018-12-13 | 2018-12-13 | Bicyclic peptide ligands specific for FAPalpha |
| PCT/GB2019/053535 WO2020120979A1 (en) | 2018-12-13 | 2019-12-13 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR FAPα |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022515721A JP2022515721A (ja) | 2022-02-22 |
| JP2022515721A5 true JP2022515721A5 (https=) | 2022-12-19 |
Family
ID=65147028
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021534207A Pending JP2022515721A (ja) | 2018-12-13 | 2019-12-13 | ＦＡＰαに特異的な二環式ペプチドリガンド |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20220008545A1 (https=) |
| EP (1) | EP3894005A1 (https=) |
| JP (1) | JP2022515721A (https=) |
| CN (1) | CN113507961A (https=) |
| GB (1) | GB201820320D0 (https=) |
| WO (1) | WO2020120979A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116474108A (zh) | 2016-12-14 | 2023-07-25 | 普渡研究基金会 | 成纤维细胞活化蛋白(fap)-靶向成像和治疗 |
| CN111118063B (zh) * | 2019-12-05 | 2023-04-18 | 吉林大学 | 以FAPα和survivin为基础的DNA及其在制备肿瘤疫苗中的应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE461212T1 (de) * | 2002-09-18 | 2010-04-15 | Prosidion Ltd | Sekundäre bindungsstelle von dipeptidylpeptidase iv (dp iv) |
| EP1452868A2 (en) | 2003-02-27 | 2004-09-01 | Pepscan Systems B.V. | Method for selecting a candidate drug compound |
| US7374898B2 (en) * | 2004-10-12 | 2008-05-20 | The Research Foundation Of State University Of New York | Peptide inhibitors against seprase |
| WO2006078161A1 (en) | 2005-01-24 | 2006-07-27 | Pepscan Systems B.V. | Binding compounds, immunogenic compounds and peptidomimetics |
| US20100047170A1 (en) * | 2006-01-05 | 2010-02-25 | Denmeade Samuel R | Peptide Prodrugs |
| EP2653545A1 (en) | 2008-02-05 | 2013-10-23 | Bicycle Therapeutics Limited | Methods and compositions |
| PL2753334T3 (pl) * | 2011-08-30 | 2022-12-12 | Trustees Of Tufts College | Aktywowane przez fap inhibitory proteasomu do leczenia guzów litych |
| CN107148425B (zh) * | 2014-10-29 | 2021-08-03 | 拜斯科阿迪有限公司 | 对mt1-mmp特异性的双环肽配体 |
| WO2016146174A1 (en) * | 2015-03-17 | 2016-09-22 | Biontech Ag | Compositions and methods for diagnosis and treatment of cancer |
| US10857196B2 (en) * | 2017-04-27 | 2020-12-08 | Bicycletx Limited | Bicyclic peptide ligands and uses thereof |
-
2018
- 2018-12-13 GB GBGB1820320.8A patent/GB201820320D0/en not_active Ceased
-
2019
- 2019-12-13 CN CN201980089032.4A patent/CN113507961A/zh active Pending
- 2019-12-13 JP JP2021534207A patent/JP2022515721A/ja active Pending
- 2019-12-13 WO PCT/GB2019/053535 patent/WO2020120979A1/en not_active Ceased
- 2019-12-13 US US17/309,628 patent/US20220008545A1/en not_active Abandoned
- 2019-12-13 EP EP19823955.0A patent/EP3894005A1/en not_active Withdrawn
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