JP2023549229A5 - - Google Patents
Info
- Publication number
- JP2023549229A5 JP2023549229A5 JP2023528449A JP2023528449A JP2023549229A5 JP 2023549229 A5 JP2023549229 A5 JP 2023549229A5 JP 2023528449 A JP2023528449 A JP 2023528449A JP 2023528449 A JP2023528449 A JP 2023528449A JP 2023549229 A5 JP2023549229 A5 JP 2023549229A5
- Authority
- JP
- Japan
- Prior art keywords
- referred
- sequence
- sar
- peptide ligand
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB2017927.1A GB202017927D0 (en) | 2020-11-13 | 2020-11-13 | Bicyclic peptide ligands specific for transferrin |
| GB2017927.1 | 2020-11-13 | ||
| GB2106903.4 | 2021-05-14 | ||
| GBGB2106903.4A GB202106903D0 (en) | 2021-05-14 | 2021-05-14 | Bicycle peptide ligands specific for transferrin |
| US202163261820P | 2021-09-29 | 2021-09-29 | |
| US63/261,820 | 2021-09-29 | ||
| PCT/GB2021/052927 WO2022101633A1 (en) | 2020-11-13 | 2021-11-12 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR TRANSFERRIN RECEPTOR 1 (TfR1) |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023549229A JP2023549229A (ja) | 2023-11-22 |
| JP2023549229A5 true JP2023549229A5 (https=) | 2024-11-21 |
| JP7848202B2 JP7848202B2 (ja) | 2026-04-20 |
Family
ID=81600834
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023528449A Active JP7848202B2 (ja) | 2020-11-13 | 2021-11-12 | トランスフェリン受容体１（ＴｆＲ１）に特異的な二環式ペプチドリガンド |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US11970555B2 (https=) |
| EP (1) | EP4244235A1 (https=) |
| JP (1) | JP7848202B2 (https=) |
| KR (1) | KR20230107589A (https=) |
| CN (1) | CN116802190A (https=) |
| AR (1) | AR126029A1 (https=) |
| AU (1) | AU2021376917A1 (https=) |
| CA (1) | CA3201414A1 (https=) |
| IL (1) | IL302713A (https=) |
| MX (1) | MX2023005624A (https=) |
| SA (1) | SA523440745B1 (https=) |
| WO (1) | WO2022101633A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20230107589A (ko) | 2020-11-13 | 2023-07-17 | 바이사이클티엑스 리미티드 | 트랜스페린 수용체 1 (TfR1)에 특이적인 비시클릭 펩티드 리간드 |
| GB202206431D0 (en) * | 2022-05-03 | 2022-06-15 | Bicycletx Ltd | Bicyclic peptide ligands specific for transferrin receptor 1 (TfR1) |
| EP4689119A1 (en) * | 2023-04-05 | 2026-02-11 | Ionis Pharmaceuticals, Inc. | Compounds and methods for reducing pln expression |
| WO2025073871A1 (en) | 2023-10-03 | 2025-04-10 | Bicycletx Limited | Bicyclic peptide ligand complexes specific for tfr1 |
| GB202316970D0 (en) * | 2023-11-06 | 2023-12-20 | Bicycletx Ltd | Bicyclic peptide ligands specific for transferrin receptor 1 (TfR1) |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2653545A1 (en) | 2008-02-05 | 2013-10-23 | Bicycle Therapeutics Limited | Methods and compositions |
| GB0914110D0 (en) | 2009-08-12 | 2009-09-16 | Medical Res Council | Peptide libraries |
| EP3218411B1 (en) * | 2014-11-14 | 2022-01-12 | Ossianix, Inc. | Variable new antigen receptors (vnars) directed against transferrin receptor (tfr) and their use |
| CN104650186A (zh) | 2015-03-09 | 2015-05-27 | 中国药科大学 | 一种能够与TfR1特异性结合的活性肽及其应用 |
| GB201706477D0 (en) * | 2017-04-24 | 2017-06-07 | Bicycle Therapeutics Ltd | Modification of polypeptides |
| US10857196B2 (en) * | 2017-04-27 | 2020-12-08 | Bicycletx Limited | Bicyclic peptide ligands and uses thereof |
| JP7670481B2 (ja) | 2017-08-04 | 2025-04-30 | バイスクルテクス・リミテッド | Ｃｄ１３７に対して特異的な二環式ペプチドリガンド |
| WO2019089395A1 (en) | 2017-11-02 | 2019-05-09 | Ossianix, Inc. | Improved tfr-selective binding peptides capable of crossing the blood brain barrier |
| CN111902429A (zh) | 2018-02-23 | 2020-11-06 | 拜斯科技术开发有限公司 | 多聚体双环肽配体 |
| WO2020084305A1 (en) | 2018-10-23 | 2020-04-30 | Bicycletx Limited | Bicyclic peptide ligands and uses thereof |
| US12492224B2 (en) * | 2018-12-21 | 2025-12-09 | Bicycletx Limited | Bicyclic peptide ligands specific for PD-L1 |
| GB201912320D0 (en) * | 2019-08-28 | 2019-10-09 | Bicycletx Ltd | PBP Binding Bicyclic Peptide Ligands |
| KR20230107589A (ko) | 2020-11-13 | 2023-07-17 | 바이사이클티엑스 리미티드 | 트랜스페린 수용체 1 (TfR1)에 특이적인 비시클릭 펩티드 리간드 |
-
2021
- 2021-11-12 KR KR1020237017137A patent/KR20230107589A/ko active Pending
- 2021-11-12 AU AU2021376917A patent/AU2021376917A1/en active Pending
- 2021-11-12 IL IL302713A patent/IL302713A/en unknown
- 2021-11-12 EP EP21819173.2A patent/EP4244235A1/en active Pending
- 2021-11-12 CA CA3201414A patent/CA3201414A1/en active Pending
- 2021-11-12 AR ARP210103150A patent/AR126029A1/es unknown
- 2021-11-12 JP JP2023528449A patent/JP7848202B2/ja active Active
- 2021-11-12 WO PCT/GB2021/052927 patent/WO2022101633A1/en not_active Ceased
- 2021-11-12 MX MX2023005624A patent/MX2023005624A/es unknown
- 2021-11-12 US US17/454,665 patent/US11970555B2/en active Active
- 2021-11-12 CN CN202180089518.5A patent/CN116802190A/zh active Pending
-
2023
- 2023-05-11 SA SA523440745A patent/SA523440745B1/ar unknown
-
2024
- 2024-03-19 US US18/610,009 patent/US20240391959A1/en not_active Abandoned
-
2025
- 2025-04-23 US US19/187,619 patent/US20250340595A1/en active Pending
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