FI119586B - Melatoniinin käyttö lääkeriippuvuudesta kärsivien potilaiden hoitoon tarkoitetun lääkkeen valmistamiseksi - Google Patents

Melatoniinin käyttö lääkeriippuvuudesta kärsivien potilaiden hoitoon tarkoitetun lääkkeen valmistamiseksi Download PDF

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Publication number
FI119586B
FI119586B FI973185A FI973185A FI119586B FI 119586 B FI119586 B FI 119586B FI 973185 A FI973185 A FI 973185A FI 973185 A FI973185 A FI 973185A FI 119586 B FI119586 B FI 119586B
Authority
FI
Finland
Prior art keywords
melatonin
benzodiazepine
drug
addiction
eller
Prior art date
Application number
FI973185A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI973185A (fi
FI973185A0 (fi
Inventor
Nava Zisapel
Original Assignee
Neurim Pharma 1991
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/381,535 external-priority patent/US6469044B1/en
Application filed by Neurim Pharma 1991 filed Critical Neurim Pharma 1991
Publication of FI973185A0 publication Critical patent/FI973185A0/fi
Publication of FI973185A publication Critical patent/FI973185A/fi
Application granted granted Critical
Publication of FI119586B publication Critical patent/FI119586B/fi

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
FI973185A 1995-02-01 1997-07-31 Melatoniinin käyttö lääkeriippuvuudesta kärsivien potilaiden hoitoon tarkoitetun lääkkeen valmistamiseksi FI119586B (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US38153595 1995-02-01
US08/381,535 US6469044B1 (en) 1995-02-01 1995-02-01 Method for treating patients suffering from drug dependencies which lead to plasma melationin deficiencies
EP95303853 1995-06-06
EP95303853A EP0724878B1 (en) 1995-02-01 1995-06-06 Use of melatonin for treating patients suffering from drug dependencies
PCT/IB1996/000082 WO1996023496A1 (en) 1995-02-01 1996-01-29 Use of melatonin for treating patients suffering from drug addiction
IB9600082 1996-01-29

Publications (3)

Publication Number Publication Date
FI973185A0 FI973185A0 (fi) 1997-07-31
FI973185A FI973185A (fi) 1997-09-30
FI119586B true FI119586B (fi) 2009-01-15

Family

ID=26140195

Family Applications (1)

Application Number Title Priority Date Filing Date
FI973185A FI119586B (fi) 1995-02-01 1997-07-31 Melatoniinin käyttö lääkeriippuvuudesta kärsivien potilaiden hoitoon tarkoitetun lääkkeen valmistamiseksi

Country Status (22)

Country Link
JP (1) JP4516159B2 (et)
CN (1) CN1083263C (et)
AT (1) AT408188B (et)
AU (1) AU695366B2 (et)
BG (1) BG62876B1 (et)
BR (1) BR9607169A (et)
CZ (1) CZ291349B6 (et)
DK (1) DK176081B1 (et)
EE (1) EE03384B1 (et)
FI (1) FI119586B (et)
IS (1) IS1980B (et)
LU (1) LU90118B1 (et)
LV (1) LV11940B (et)
MD (1) MD1716C2 (et)
NO (1) NO312814B1 (et)
NZ (1) NZ298878A (et)
PL (1) PL183148B1 (et)
SI (1) SI9620022A (et)
SK (1) SK284521B6 (et)
TR (1) TR199700723T1 (et)
TW (1) TW483757B (et)
WO (1) WO1996023496A1 (et)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1272177B1 (en) 2000-01-05 2007-04-11 Neurim Pharmaceuticals (1991) Limited Method and formulation for treating resistance to antihypertensives and related conditions
IL149377A (en) * 2002-04-28 2012-10-31 Neurim Pharma 1991 Pharmaceutical formulation comprising melatonin for the potentiation of the effect of hypnotic compounds
IL155666A (en) 2003-04-29 2013-12-31 Neurim Pharma 1991 Insomnia treatment
US9119846B2 (en) 2003-04-29 2015-09-01 Neurim Pharmaceuticals (1991) Ltd. Method and composition for enhancing cognition in alzheimer's patients
US11918557B2 (en) 2012-01-26 2024-03-05 Vanda Pharmaceuticals Inc. Treatment of circadian rhythm disorders
KR102317399B1 (ko) 2012-01-26 2021-10-26 반다 파마슈티칼즈, 인코퍼레이티드. 일주기 리듬 장애의 치료
CN105142630A (zh) 2012-12-18 2015-12-09 万达制药公司 昼夜节律紊乱的治疗
US10376487B2 (en) 2013-11-12 2019-08-13 Vanda Pharmaceuticals Inc. Method of treatment
US11090285B2 (en) 2013-11-12 2021-08-17 Vanda Pharmaceuticals Inc Treatment of circadian rhythm disorders
EP3777842A1 (en) * 2016-10-31 2021-02-17 Neurim Pharmaceuticals Ltd. Melatonin mini-tablets and method of manufacturing the same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2134789T3 (es) * 1991-05-09 1999-10-16 Neurim Pharma 1991 Composiciones que contienen melatonina.
IT1251544B (it) * 1991-05-13 1995-05-17 Gabriele Biella Composizioni farmaceutiche attive nella terapia dei disturbi del sonno comprendenti melatonina o un suo derivato in associazione con un derivato benzodiazepinico

Also Published As

Publication number Publication date
IS1980B (is) 2005-01-14
LU90118B1 (fr) 1997-11-13
CZ240597A3 (cs) 1998-01-14
MD1716C2 (ro) 2002-02-28
AU4457496A (en) 1996-08-21
DK89697A (da) 1997-07-30
BG101803A (en) 1998-04-30
AU695366B2 (en) 1998-08-13
DK176081B1 (da) 2006-04-18
CN1083263C (zh) 2002-04-24
PL183148B1 (pl) 2002-05-31
SI9620022A (sl) 1998-10-31
BR9607169A (pt) 1997-11-11
TR199700723T1 (xx) 1998-02-21
MD1716B2 (en) 2001-08-31
NO973531L (no) 1997-09-30
AT408188B (de) 2001-09-25
BG62876B1 (bg) 2000-10-31
PL321630A1 (en) 1997-12-08
NO973531D0 (no) 1997-07-31
SK103097A3 (en) 1998-01-14
JPH10513177A (ja) 1998-12-15
EE03384B1 (et) 2001-04-16
CN1172431A (zh) 1998-02-04
LV11940A (lv) 1998-01-20
NZ298878A (en) 1999-05-28
CZ291349B6 (cs) 2003-02-12
MD970254A (en) 1999-05-31
JP4516159B2 (ja) 2010-08-04
MX9705856A (es) 1998-07-31
ATA901396A (de) 2001-02-15
LV11940B (en) 1998-05-20
NO312814B1 (no) 2002-07-08
TW483757B (en) 2002-04-21
FI973185A (fi) 1997-09-30
SK284521B6 (sk) 2005-05-05
WO1996023496A1 (en) 1996-08-08
FI973185A0 (fi) 1997-07-31
EE9700166A (et) 1998-02-16
IS4532A (is) 1997-07-25

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