EE03384B1 - Melatoniini kasutamine ravimi tootmiseks - Google Patents

Melatoniini kasutamine ravimi tootmiseks

Info

Publication number
EE03384B1
EE03384B1 EE9700166A EE9700166A EE03384B1 EE 03384 B1 EE03384 B1 EE 03384B1 EE 9700166 A EE9700166 A EE 9700166A EE 9700166 A EE9700166 A EE 9700166A EE 03384 B1 EE03384 B1 EE 03384B1
Authority
EE
Estonia
Prior art keywords
melatonin
medicament
manufacture
Prior art date
Application number
EE9700166A
Other languages
English (en)
Other versions
EE9700166A (et
Inventor
Zisapel Nava
Original Assignee
Neurim Pharmaceuticals (1991) Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/381,535 external-priority patent/US6469044B1/en
Application filed by Neurim Pharmaceuticals (1991) Ltd. filed Critical Neurim Pharmaceuticals (1991) Ltd.
Publication of EE9700166A publication Critical patent/EE9700166A/et
Publication of EE03384B1 publication Critical patent/EE03384B1/et

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
EE9700166A 1995-02-01 1996-01-29 Melatoniini kasutamine ravimi tootmiseks EE03384B1 (et)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/381,535 US6469044B1 (en) 1995-02-01 1995-02-01 Method for treating patients suffering from drug dependencies which lead to plasma melationin deficiencies
EP95303853A EP0724878B1 (en) 1995-02-01 1995-06-06 Use of melatonin for treating patients suffering from drug dependencies
PCT/IB1996/000082 WO1996023496A1 (en) 1995-02-01 1996-01-29 Use of melatonin for treating patients suffering from drug addiction

Publications (2)

Publication Number Publication Date
EE9700166A EE9700166A (et) 1998-02-16
EE03384B1 true EE03384B1 (et) 2001-04-16

Family

ID=26140195

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9700166A EE03384B1 (et) 1995-02-01 1996-01-29 Melatoniini kasutamine ravimi tootmiseks

Country Status (22)

Country Link
JP (1) JP4516159B2 (et)
CN (1) CN1083263C (et)
AT (1) AT408188B (et)
AU (1) AU695366B2 (et)
BG (1) BG62876B1 (et)
BR (1) BR9607169A (et)
CZ (1) CZ291349B6 (et)
DK (1) DK176081B1 (et)
EE (1) EE03384B1 (et)
FI (1) FI119586B (et)
IS (1) IS1980B (et)
LU (1) LU90118B1 (et)
LV (1) LV11940B (et)
MD (1) MD1716C2 (et)
NO (1) NO312814B1 (et)
NZ (1) NZ298878A (et)
PL (1) PL183148B1 (et)
SI (1) SI9620022A (et)
SK (1) SK284521B6 (et)
TR (1) TR199700723T1 (et)
TW (1) TW483757B (et)
WO (1) WO1996023496A1 (et)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1272177E (pt) 2000-01-05 2007-07-11 Neurim Pharma 1991 Método e formulação para o tratamento da resistência aos antihipertensos e condições associadas.
IL149377A (en) * 2002-04-28 2012-10-31 Neurim Pharma 1991 Pharmaceutical formulation comprising melatonin for the potentiation of the effect of hypnotic compounds
US9119846B2 (en) 2003-04-29 2015-09-01 Neurim Pharmaceuticals (1991) Ltd. Method and composition for enhancing cognition in alzheimer's patients
IL155666A (en) 2003-04-29 2013-12-31 Neurim Pharma 1991 Insomnia treatment
US11918557B2 (en) 2012-01-26 2024-03-05 Vanda Pharmaceuticals Inc. Treatment of circadian rhythm disorders
AU2013211880A1 (en) * 2012-01-26 2014-08-21 Vanda Pharmaceuticals Inc. Treatment of circadian rhythm disorders
EP3767297A1 (en) 2012-12-18 2021-01-20 Vanda Pharmaceuticals Inc. Method of determining tau and thereby determining whether a patient has a free-running circadian rhythm
US11090285B2 (en) 2013-11-12 2021-08-17 Vanda Pharmaceuticals Inc Treatment of circadian rhythm disorders
US10376487B2 (en) 2013-11-12 2019-08-13 Vanda Pharmaceuticals Inc. Method of treatment
EP3777842A1 (en) * 2016-10-31 2021-02-17 Neurim Pharmaceuticals Ltd. Melatonin mini-tablets and method of manufacturing the same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE181670T1 (de) * 1991-05-09 1999-07-15 Neurim Pharma 1991 Melatonin enthaltende arzneimittel
IT1251544B (it) * 1991-05-13 1995-05-17 Gabriele Biella Composizioni farmaceutiche attive nella terapia dei disturbi del sonno comprendenti melatonina o un suo derivato in associazione con un derivato benzodiazepinico

Also Published As

Publication number Publication date
LU90118B1 (fr) 1997-11-13
TW483757B (en) 2002-04-21
ATA901396A (de) 2001-02-15
AU4457496A (en) 1996-08-21
JP4516159B2 (ja) 2010-08-04
FI119586B (fi) 2009-01-15
MD1716B2 (en) 2001-08-31
IS1980B (is) 2005-01-14
PL321630A1 (en) 1997-12-08
LV11940B (en) 1998-05-20
IS4532A (is) 1997-07-25
DK176081B1 (da) 2006-04-18
CZ240597A3 (cs) 1998-01-14
CN1083263C (zh) 2002-04-24
AU695366B2 (en) 1998-08-13
TR199700723T1 (xx) 1998-02-21
MX9705856A (es) 1998-07-31
SK103097A3 (en) 1998-01-14
EE9700166A (et) 1998-02-16
DK89697A (da) 1997-07-30
CN1172431A (zh) 1998-02-04
FI973185A (fi) 1997-09-30
MD970254A (en) 1999-05-31
WO1996023496A1 (en) 1996-08-08
BG62876B1 (bg) 2000-10-31
JPH10513177A (ja) 1998-12-15
FI973185A0 (fi) 1997-07-31
NO312814B1 (no) 2002-07-08
NO973531L (no) 1997-09-30
LV11940A (lv) 1998-01-20
MD1716C2 (ro) 2002-02-28
BR9607169A (pt) 1997-11-11
PL183148B1 (pl) 2002-05-31
AT408188B (de) 2001-09-25
NZ298878A (en) 1999-05-28
SI9620022A (sl) 1998-10-31
NO973531D0 (no) 1997-07-31
BG101803A (en) 1998-04-30
SK284521B6 (sk) 2005-05-05
CZ291349B6 (cs) 2003-02-12

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Legal Events

Date Code Title Description
KB4A Valid patent at the end of a year

Effective date: 20021231

KB4A Valid patent at the end of a year

Effective date: 20031231

KB4A Valid patent at the end of a year

Effective date: 20041231

KB4A Valid patent at the end of a year

Effective date: 20051231

KB4A Valid patent at the end of a year

Effective date: 20061231

MM4A Lapsed by not paying the annual fees

Effective date: 20070129