FI112229B - Menetelmä uusien, terapeuttisesti käyttökelpoisten 1,2,4-oksadiatsolyyli-fenoksialkyyli-isoksatsolien valmistamiseksi - Google Patents
Menetelmä uusien, terapeuttisesti käyttökelpoisten 1,2,4-oksadiatsolyyli-fenoksialkyyli-isoksatsolien valmistamiseksi Download PDFInfo
- Publication number
- FI112229B FI112229B FI931707A FI931707A FI112229B FI 112229 B FI112229 B FI 112229B FI 931707 A FI931707 A FI 931707A FI 931707 A FI931707 A FI 931707A FI 112229 B FI112229 B FI 112229B
- Authority
- FI
- Finland
- Prior art keywords
- formula
- alkoxy
- compound
- alkyl
- alkoxyalkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/869,287 US5349068A (en) | 1992-04-15 | 1992-04-15 | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents |
US86928792 | 1992-04-15 |
Publications (3)
Publication Number | Publication Date |
---|---|
FI931707A0 FI931707A0 (fi) | 1993-04-15 |
FI931707A FI931707A (fi) | 1993-10-16 |
FI112229B true FI112229B (fi) | 2003-11-14 |
Family
ID=25353269
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI931707A FI112229B (fi) | 1992-04-15 | 1993-04-15 | Menetelmä uusien, terapeuttisesti käyttökelpoisten 1,2,4-oksadiatsolyyli-fenoksialkyyli-isoksatsolien valmistamiseksi |
Country Status (26)
Country | Link |
---|---|
US (3) | US5349068A (zh) |
EP (1) | EP0566199B1 (zh) |
JP (1) | JP3103845B2 (zh) |
KR (1) | KR100314158B1 (zh) |
AT (1) | ATE189958T1 (zh) |
AU (1) | AU666528B2 (zh) |
CA (1) | CA2094012C (zh) |
CZ (1) | CZ285845B6 (zh) |
DE (1) | DE69327913T2 (zh) |
DK (1) | DK0566199T3 (zh) |
ES (1) | ES2143487T3 (zh) |
FI (1) | FI112229B (zh) |
GR (1) | GR3033486T3 (zh) |
HU (2) | HU220606B1 (zh) |
IL (1) | IL105372A (zh) |
MX (1) | MX9302169A (zh) |
MY (1) | MY110191A (zh) |
NO (1) | NO302700B1 (zh) |
NZ (1) | NZ247411A (zh) |
PH (1) | PH30454A (zh) |
PT (1) | PT566199E (zh) |
RU (1) | RU2114112C1 (zh) |
SG (1) | SG50663A1 (zh) |
SK (1) | SK279786B6 (zh) |
TW (1) | TW239140B (zh) |
UA (1) | UA35557C2 (zh) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5349068A (en) * | 1992-04-15 | 1994-09-20 | Sterling Winthrop Inc. | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents |
US5552420A (en) * | 1994-05-13 | 1996-09-03 | Sterling Winthrop Inc. | Therapeutic phenoxyalkylazoles and phenoxyalkylazines |
IL118657A0 (en) * | 1996-06-14 | 1996-10-16 | Arad Dorit | Inhibitors for picornavirus proteases |
IL122591A0 (en) | 1997-12-14 | 1998-06-15 | Arad Dorit | Pharmaceutical compositions comprising cystein protease inhibitors |
US6528652B1 (en) * | 1999-01-21 | 2003-03-04 | Chronimed | Composition and device for detecting leukocytes in urine |
US6348324B1 (en) | 1999-01-21 | 2002-02-19 | Hypoguard America Limited | Composition and device for detecting leukocytes in urine |
AUPQ105499A0 (en) | 1999-06-18 | 1999-07-08 | Biota Scientific Management Pty Ltd | Antiviral agents |
AUPR213700A0 (en) * | 2000-12-18 | 2001-01-25 | Biota Scientific Management Pty Ltd | Antiviral agents |
KR20040004705A (ko) * | 2001-06-08 | 2004-01-13 | 시토비아 인크. | 카스파제의 활성제 및 아폽토시스의 유도제로서의 치환된3-아릴-5-아릴-[1,2,4]-옥사디아졸과 유사체 및 이의 용도 |
US7129359B2 (en) * | 2002-07-09 | 2006-10-31 | National Health Research Institutes | Imidazolidinone compounds |
CA2459375A1 (en) * | 2001-08-29 | 2003-03-13 | Viropharma Incorporated | Oxadiazolyl-phenoxyalkylisoxazoles, compositions thereof and methods for their use as anti-picornaviral agents |
CA2459376A1 (en) * | 2001-08-29 | 2003-03-13 | Viropharma Incorporated | Oxadiazolyl-phenoxyalkylisoxazoles, compositions thereof and methods for their use as anti-picornaviral agents |
ATE522212T1 (de) | 2001-12-07 | 2011-09-15 | Ana Maria Sandino | Neomycin zur steigerung des überlebens von wassertieren, die einem ipnv ausgesetzt sind |
US20060167109A1 (en) * | 2002-02-14 | 2006-07-27 | Pevear Daniel C | Methods of reducing rhinovirus contagion and related compositions |
WO2004058253A1 (en) * | 2002-12-18 | 2004-07-15 | Cytovia, Inc. | 3,5-disubstituted-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof |
US7259174B2 (en) * | 2004-05-25 | 2007-08-21 | National Health Research Institutes | Imidazolidinone compounds |
JP2008509143A (ja) * | 2004-08-04 | 2008-03-27 | シェーリング コーポレイション | 気道疾患の処置のためのプレコナリルを含む薬学的処方物 |
US20070202055A1 (en) * | 2006-02-09 | 2007-08-30 | Julianne Berry | Pharmaceutical Formulations |
MX2008010350A (es) * | 2006-02-09 | 2008-10-31 | Schering Corp | Formulaciones farmaceuticas. |
AR059357A1 (es) * | 2006-02-09 | 2008-03-26 | Schering Corp | Formulaciones farmaceuticas |
RU2469032C2 (ru) | 2006-12-13 | 2012-12-10 | Ф.Хоффманн-Ля Рош Аг | Производные 2-(пиперидин-4-ил)-4-фенокси- или фениламинопиримидина в качестве ненуклеозидных ингибиторов обратной транскриптазы |
KR101031584B1 (ko) * | 2009-04-21 | 2011-04-27 | 파인오토시스템(주) | 전면부가 개폐되는 차량용 적외선 조사장치 |
CN103102348B (zh) * | 2011-11-14 | 2016-06-08 | 上海交通大学 | 噁二唑类化合物及其制备方法、药物组合物及其用途 |
AU2019324089B2 (en) | 2018-08-21 | 2024-06-13 | Kyorin Pharmaceutical Co., Ltd. | Bicyclic heteroaromatic ring derivative |
WO2021209563A1 (en) | 2020-04-16 | 2021-10-21 | Som Innovation Biotech, S.A. | Compounds for use in the treatment of viral infections by respiratory syndrome-related coronavirus |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1299176C (en) * | 1985-07-02 | 1992-04-21 | Guy Dominic Diana | Process for preparing isoxazole and furan derivatives |
ZA846525B (en) * | 1983-08-29 | 1985-04-24 | Sterling Drug Inc | (substituted)phenyl-aliphatic-isoxazoles useful as antiviral agents and preparation thereof |
US4843087A (en) * | 1983-08-29 | 1989-06-27 | Sterling Drug Inc. | Di-heterocyclic compounds and their use as antiviral agents |
US4861791A (en) * | 1983-08-29 | 1989-08-29 | Sterling Drug Inc. | Dihydro-oxazolyl substituted-phenyl-aliphatic lower alkyl and their use as antiviral agents |
NZ234760A (en) * | 1989-08-18 | 1991-09-25 | Sterling Drug Inc | Antiviral oxazole compounds and compositions |
US5175178A (en) * | 1989-08-21 | 1992-12-29 | Sterling Drug Inc. | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents |
US4942241A (en) * | 1989-08-21 | 1990-07-17 | Sterling Drug Inc. | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents |
US4945164A (en) * | 1989-08-18 | 1990-07-31 | Sterling Drug Inc. | 1,3,4-Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents and intermediates thereof |
US5175177A (en) * | 1991-07-17 | 1992-12-29 | Sterling Drug Inc. | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents |
US5349068A (en) * | 1992-04-15 | 1994-09-20 | Sterling Winthrop Inc. | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents |
-
1992
- 1992-04-15 US US07/869,287 patent/US5349068A/en not_active Expired - Lifetime
-
1993
- 1993-03-31 TW TW082102383A patent/TW239140B/zh not_active IP Right Cessation
- 1993-04-07 CZ CZ93597A patent/CZ285845B6/cs not_active IP Right Cessation
- 1993-04-10 MY MYPI93000665A patent/MY110191A/en unknown
- 1993-04-13 EP EP93201058A patent/EP0566199B1/en not_active Expired - Lifetime
- 1993-04-13 SG SG1996008085A patent/SG50663A1/en unknown
- 1993-04-13 PT PT93201058T patent/PT566199E/pt unknown
- 1993-04-13 DK DK93201058T patent/DK0566199T3/da active
- 1993-04-13 DE DE69327913T patent/DE69327913T2/de not_active Expired - Lifetime
- 1993-04-13 AT AT93201058T patent/ATE189958T1/de active
- 1993-04-13 ES ES93201058T patent/ES2143487T3/es not_active Expired - Lifetime
- 1993-04-14 IL IL10537293A patent/IL105372A/en not_active IP Right Cessation
- 1993-04-14 MX MX9302169A patent/MX9302169A/es unknown
- 1993-04-14 NO NO19931366A patent/NO302700B1/no not_active IP Right Cessation
- 1993-04-14 AU AU36881/93A patent/AU666528B2/en not_active Expired
- 1993-04-14 PH PH46044A patent/PH30454A/en unknown
- 1993-04-14 HU HU9301084A patent/HU220606B1/hu unknown
- 1993-04-14 RU RU93004675A patent/RU2114112C1/ru active
- 1993-04-14 KR KR1019930006244A patent/KR100314158B1/ko not_active IP Right Cessation
- 1993-04-14 CA CA002094012A patent/CA2094012C/en not_active Expired - Lifetime
- 1993-04-15 SK SK353-93A patent/SK279786B6/sk not_active IP Right Cessation
- 1993-04-15 JP JP05088647A patent/JP3103845B2/ja not_active Expired - Lifetime
- 1993-04-15 FI FI931707A patent/FI112229B/fi not_active IP Right Cessation
- 1993-04-15 NZ NZ247411A patent/NZ247411A/en not_active IP Right Cessation
- 1993-06-15 UA UA93003099A patent/UA35557C2/uk unknown
- 1993-10-01 US US08/131,050 patent/US5464848A/en not_active Expired - Lifetime
-
1995
- 1995-05-19 US US08/444,795 patent/US5643929A/en not_active Expired - Lifetime
- 1995-06-30 HU HU95P/P00642P patent/HU211320A9/hu unknown
-
2000
- 2000-05-24 GR GR20000401183T patent/GR3033486T3/el unknown
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
GB | Transfer or assigment of application |
Owner name: SANOFI |
|
PC | Transfer of assignment of patent |
Owner name: SANOFI |
|
MA | Patent expired |