FI111639B - Menetelmä uusien, terapeuttisesti käyttökelpoisten piperatsiini- ja piperidiinijohdannaisten valmistamiseksi - Google Patents

Menetelmä uusien, terapeuttisesti käyttökelpoisten piperatsiini- ja piperidiinijohdannaisten valmistamiseksi Download PDF

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FI111639B
FI111639B FI932104A FI932104A FI111639B FI 111639 B FI111639 B FI 111639B FI 932104 A FI932104 A FI 932104A FI 932104 A FI932104 A FI 932104A FI 111639 B FI111639 B FI 111639B
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FI932104A
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FI932104A0 (fi
FI932104A (fi
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Allen B Reitz
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Mcneilab Inc
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    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/66—Nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

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FI932104A 1991-09-11 1993-05-10 Menetelmä uusien, terapeuttisesti käyttökelpoisten piperatsiini- ja piperidiinijohdannaisten valmistamiseksi FI111639B (fi)

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US75788191A 1991-09-11 1991-09-11
US75788191 1991-09-11
PCT/US1992/007754 WO1993004682A1 (en) 1991-09-11 1992-09-11 Novel 4-arylpiperazines and 4-arylpiperidines
US9207754 1992-09-11

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WO1993004684A1 (en) 1993-03-18
HU9301361D0 (en) 1993-09-28
FI932104A0 (fi) 1993-05-10
EP0563345A4 (en) 1994-09-28
JPH06502870A (ja) 1994-03-31
SG70980A1 (en) 2000-03-21
NZ240863A (en) 1995-04-27
ES2179822T3 (es) 2003-02-01
EP0562049A1 (en) 1993-09-29
JP2941945B2 (ja) 1999-08-30
KR100196249B1 (ko) 1999-06-15
NO303780B1 (no) 1998-08-31
FI932103A0 (fi) 1993-05-10
JPH06502183A (ja) 1994-03-10
DK0563345T3 (da) 2002-10-14
TW209867B (no) 1993-07-21
MX9102407A (es) 1994-05-31
EP0563345B1 (en) 2002-07-03
DE69232665T2 (de) 2002-11-28
NO931695D0 (no) 1993-05-10
PT99700A (pt) 1993-03-31
DE69232665D1 (de) 2002-08-08
FI932103A (fi) 1993-05-10
EP0562049A4 (en) 1994-09-28
HU217068B (hu) 1999-11-29
NO931694L (no) 1993-06-30
NO931694D0 (no) 1993-05-10
AU657799B2 (en) 1995-03-23
HU9301362D0 (en) 1993-09-28
ZA919629B (en) 1993-12-06
FI932104A (fi) 1993-05-10
AU1363392A (en) 1993-04-05
CA2095826A1 (en) 1993-03-12
NO931695L (no) 1993-05-27
IE914218A1 (en) 1993-03-24
RU2139867C1 (ru) 1999-10-20
WO1993004682A1 (en) 1993-03-18
HUT68963A (en) 1995-08-28
EP0563345A1 (en) 1993-10-06
AU2659992A (en) 1993-04-05
CA2095847A1 (en) 1993-03-12
HUT64535A (en) 1994-01-28
ATE219938T1 (de) 2002-07-15

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