FI106719B - Menetelmä terapeuttisesti käyttökelpoisten [1,2,4]triatsolo[4,3-a]kinoksaliini-1,4-dionien ja -4-onien valmistamiseksi - Google Patents

Menetelmä terapeuttisesti käyttökelpoisten [1,2,4]triatsolo[4,3-a]kinoksaliini-1,4-dionien ja -4-onien valmistamiseksi Download PDF

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Publication number
FI106719B
FI106719B FI941287A FI941287A FI106719B FI 106719 B FI106719 B FI 106719B FI 941287 A FI941287 A FI 941287A FI 941287 A FI941287 A FI 941287A FI 106719 B FI106719 B FI 106719B
Authority
FI
Finland
Prior art keywords
compound
formula
triazolo
quinoxaline
dione
Prior art date
Application number
FI941287A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI941287A (fi
FI941287A0 (fi
Inventor
Poul Jacobsen
Flemming Elmelund Nielsen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of FI941287A publication Critical patent/FI941287A/fi
Publication of FI941287A0 publication Critical patent/FI941287A0/fi
Application granted granted Critical
Publication of FI106719B publication Critical patent/FI106719B/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
FI941287A 1991-09-20 1994-03-18 Menetelmä terapeuttisesti käyttökelpoisten [1,2,4]triatsolo[4,3-a]kinoksaliini-1,4-dionien ja -4-onien valmistamiseksi FI106719B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DK162491 1991-09-20
DK911624A DK162491D0 (da) 1991-09-20 1991-09-20 Heterocycliske forbindelser, deres fremstilling og farmaceutiske praeparater indeholdende forbindelserne
PCT/DK1992/000271 WO1993006103A1 (en) 1991-09-20 1992-09-09 Triazoloquinoxalin-1,4-diones and their preparation and use
DK9200271 1992-09-09

Publications (3)

Publication Number Publication Date
FI941287A FI941287A (fi) 1994-03-18
FI941287A0 FI941287A0 (fi) 1994-03-18
FI106719B true FI106719B (fi) 2001-03-30

Family

ID=8106648

Family Applications (1)

Application Number Title Priority Date Filing Date
FI941287A FI106719B (fi) 1991-09-20 1994-03-18 Menetelmä terapeuttisesti käyttökelpoisten [1,2,4]triatsolo[4,3-a]kinoksaliini-1,4-dionien ja -4-onien valmistamiseksi

Country Status (13)

Country Link
US (1) US5504085A (no)
EP (1) EP0633885A1 (no)
JP (1) JPH07501791A (no)
AU (1) AU663523B2 (no)
CA (1) CA2119579A1 (no)
DK (1) DK162491D0 (no)
FI (1) FI106719B (no)
IL (1) IL103160A (no)
NO (1) NO302368B1 (no)
NZ (1) NZ244398A (no)
TW (1) TW210341B (no)
WO (1) WO1993006103A1 (no)
ZA (1) ZA927172B (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1041931C (zh) * 1993-05-06 1999-02-03 诺沃-诺迪斯克有限公司 [1,2,4]三唑并[4,3－a]喹喔啉化合物,它们的制备及其应用
KR100364947B1 (ko) * 1994-02-14 2003-03-06 메렐 파마슈티칼스 인크. 엔케팔리나제및ace의억제제로서유용한신규의머캅토아세틸아미도1,3,4,5-테트라히드로-벤조[c]아제핀-3-온디술파이드유도체
FR2717814B1 (fr) * 1994-03-28 1996-04-26 Rhone Poulenc Rorer Sa Dérivés de 1,2,4-triazolo(4,3-a)pyrazine-4-one, leur préparation et les médicaments les contenant.
FR2717813B1 (fr) * 1994-03-28 1996-05-10 Rhone Poulenc Rorer Sa Dérivés d'imidazo[1,2-a]indeno[1,2-e]pyrazine-4-one, leur préparation et les médicaments les contenant .
FR2717812B1 (fr) * 1994-03-28 1996-05-10 Rhone Poulenc Rorer Sa Indeno[1,2-e]pyrazine-4-ones, leur préparation et les médicaments les contenant.
FR2717805B1 (fr) * 1994-03-28 1996-05-10 Rhone Poulenc Rorer Sa Dérivés de 5H-indeno[1,2-b]pyrazine-2,3-dione, leur préparation et les médicaments les contenant .
FR2722789B1 (fr) * 1994-07-20 1996-08-23 Rhone Poulenc Rorer Sa Derives d'acide imidazo (1,2-a)indeno(1,2-e) pyrazine-2-carboxylique, leur preparation et les medicaments les contenant
CZ284930B6 (cs) * 1994-09-16 1999-04-14 Novo Nordisk A/S [1,2,4]triazolo[4,3-a]chinoxalinonové deriváty, jejich příprava a použití
DK0783504T3 (da) * 1994-09-16 2000-08-14 Novo Nordisk As (1,2,4)triazolo (4,3-a)guinoxalinon-derivater, deres fremstilling og anvendelse som antagonister af ampa-receptorer
US5679680A (en) * 1995-02-16 1997-10-21 Warner-Lambert Company α-substituted hydrazides having calpain inhibitory activity
USRE37234E1 (en) * 1996-11-01 2001-06-19 Nitromed, Inc. Nitrosated and nitrosylated phosphodiestrase inhibitor compounds, compositions and their uses
US5958926A (en) 1996-11-01 1999-09-28 Nitromed, Inc. Nitrosated and nitrosylated phosphodiesterase inhibitor compounds, compositions and their uses
IL125950A0 (en) * 1997-09-05 1999-04-11 Pfizer Prod Inc Methods of administering ampa receptor antagonists to treat dyskinesias associated with dopamine agonist therapy
US20040152694A1 (en) * 2003-02-04 2004-08-05 Istvan Kurucz Methods and compositions for treating inflammatory disorders of the airways
CA2671980C (en) * 2006-12-13 2015-05-05 Aska Pharmaceutical Co., Ltd. Quinoxaline derivatives
EP2338492A1 (en) 2009-12-24 2011-06-29 Universidad del Pais Vasco Methods and compositions for the treatment of alzheimer
CA2810659A1 (en) 2010-09-07 2012-03-15 Astellas Pharma Inc. Quinoxaline compound

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4400382A (en) * 1980-05-09 1983-08-23 Usv Pharmaceutical Corporation Thiazoloquinoxalin-1,4-diones for treating allergy
US4354027A (en) * 1980-05-19 1982-10-12 Usv Pharmaceutical Corporation Triazoloquinoxalin-4-ones
US4623725A (en) * 1982-10-18 1986-11-18 Pfizer Inc. [1,2,4]Triazolo[4,3-a]quinoxaline-4-amine derivatives
US4780464A (en) * 1986-12-08 1988-10-25 Warner-Lambert Company (1,2,4)triazolo(4,3-a)quinoxaline-4-amines
DK160941C (da) * 1988-06-28 1991-10-21 Novo Nordisk As Kondenserede 2,3-dihydroxypyraziner, fremgangsmaade til deres fremstilling og farmaceutiske praeparater, hvori forbindelserne indgaar
US4975430A (en) * 1989-06-16 1990-12-04 The State Of Oregon Acting By And Through The State Board Of Education On Behalf Of The Oregon Health Sciences University CNQX and its analogs as therapeutics for degenerative neural diseases
DE69132340T2 (de) * 1990-11-06 2001-02-08 Yamanouchi Pharma Co Ltd Kondensiertes pyrazinderivat
PT101004B (pt) * 1991-10-26 1999-10-29 Schering Ag Derivados da quinoxalina, processo para a sua preparacao e composicoes farmaceuticas que os contem
FR2690160A1 (fr) * 1992-04-15 1993-10-22 Rhone Poulenc Rorer Sa Application de dérivés d'acide 2H-1,2,4-benzothiadiazine-1,1-dioxyde-3-carboxylique à la préparation de médicaments, les produits nouveaux, leur préparation et les médicaments les contenant.

Also Published As

Publication number Publication date
US5504085A (en) 1996-04-02
NO940989D0 (no) 1994-03-18
FI941287A (fi) 1994-03-18
EP0633885A1 (en) 1995-01-18
NZ244398A (en) 1995-02-24
CA2119579A1 (en) 1993-04-01
NO302368B1 (no) 1998-02-23
TW210341B (no) 1993-08-01
IL103160A0 (en) 1993-02-21
NO940989L (no) 1994-03-18
WO1993006103A1 (en) 1993-04-01
AU663523B2 (en) 1995-10-12
AU2660092A (en) 1993-04-27
DK162491D0 (da) 1991-09-20
FI941287A0 (fi) 1994-03-18
IL103160A (en) 1999-08-17
ZA927172B (en) 1993-03-24
JPH07501791A (ja) 1995-02-23

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