IL103160A - Pharmaceuticals Containing 1,2,4 [Triazolo] -A] 4,3 Quinoxaline-4-Ones and 1,4Dions for the treatment of indications related to neurotransmitter overactivity - Google Patents

Pharmaceuticals Containing 1,2,4 [Triazolo] -A] 4,3 Quinoxaline-4-Ones and 1,4Dions for the treatment of indications related to neurotransmitter overactivity

Info

Publication number
IL103160A
IL103160A IL10316092A IL10316092A IL103160A IL 103160 A IL103160 A IL 103160A IL 10316092 A IL10316092 A IL 10316092A IL 10316092 A IL10316092 A IL 10316092A IL 103160 A IL103160 A IL 103160A
Authority
IL
Israel
Prior art keywords
compound
quinoxaline
dione
triazolo
formula
Prior art date
Application number
IL10316092A
Other languages
English (en)
Hebrew (he)
Other versions
IL103160A0 (en
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of IL103160A0 publication Critical patent/IL103160A0/xx
Publication of IL103160A publication Critical patent/IL103160A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL10316092A 1991-09-20 1992-09-14 Pharmaceuticals Containing 1,2,4 [Triazolo] -A] 4,3 Quinoxaline-4-Ones and 1,4Dions for the treatment of indications related to neurotransmitter overactivity IL103160A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK911624A DK162491D0 (da) 1991-09-20 1991-09-20 Heterocycliske forbindelser, deres fremstilling og farmaceutiske praeparater indeholdende forbindelserne

Publications (2)

Publication Number Publication Date
IL103160A0 IL103160A0 (en) 1993-02-21
IL103160A true IL103160A (en) 1999-08-17

Family

ID=8106648

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10316092A IL103160A (en) 1991-09-20 1992-09-14 Pharmaceuticals Containing 1,2,4 [Triazolo] -A] 4,3 Quinoxaline-4-Ones and 1,4Dions for the treatment of indications related to neurotransmitter overactivity

Country Status (13)

Country Link
US (1) US5504085A (no)
EP (1) EP0633885A1 (no)
JP (1) JPH07501791A (no)
AU (1) AU663523B2 (no)
CA (1) CA2119579A1 (no)
DK (1) DK162491D0 (no)
FI (1) FI106719B (no)
IL (1) IL103160A (no)
NO (1) NO302368B1 (no)
NZ (1) NZ244398A (no)
TW (1) TW210341B (no)
WO (1) WO1993006103A1 (no)
ZA (1) ZA927172B (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994026746A1 (en) * 1993-05-06 1994-11-24 Novo Nordisk A/S [1,2,4]TRIAZOLO[4,3-a]QUINOXALINE COMPOUNDS, THEIR PREPARATION AND USE
HUT74385A (en) * 1994-02-14 1996-12-30 Merrell Pharma Inc Novel mercaptoacetylamido 1,3,4,5-tetrahydro-benzo[c]azepin-3-one disulfide derivatives useful as inhibitors of enkephalinase and ace
FR2717805B1 (fr) * 1994-03-28 1996-05-10 Rhone Poulenc Rorer Sa Dérivés de 5H-indeno[1,2-b]pyrazine-2,3-dione, leur préparation et les médicaments les contenant .
FR2717813B1 (fr) * 1994-03-28 1996-05-10 Rhone Poulenc Rorer Sa Dérivés d'imidazo[1,2-a]indeno[1,2-e]pyrazine-4-one, leur préparation et les médicaments les contenant .
FR2717814B1 (fr) * 1994-03-28 1996-04-26 Rhone Poulenc Rorer Sa Dérivés de 1,2,4-triazolo(4,3-a)pyrazine-4-one, leur préparation et les médicaments les contenant.
FR2717812B1 (fr) * 1994-03-28 1996-05-10 Rhone Poulenc Rorer Sa Indeno[1,2-e]pyrazine-4-ones, leur préparation et les médicaments les contenant.
FR2722789B1 (fr) * 1994-07-20 1996-08-23 Rhone Poulenc Rorer Sa Derives d'acide imidazo (1,2-a)indeno(1,2-e) pyrazine-2-carboxylique, leur preparation et les medicaments les contenant
DE69515680T2 (de) * 1994-09-16 2000-10-19 Novo Nordisk As [1,2,4]TRIAZOLO[4,3-a]CHINOXYLINONDERIVATE, IHRE DARSTELLUNG UND VERWENDUNG ALS ANTAGONISTEN VON AMPA-REZEPTOREN
WO1996008493A1 (en) * 1994-09-16 1996-03-21 Novo Nordisk A/S [1,2,4]TRIAZOLO[4,3-a]QUINOXALINONE DERIVATIVES, THEIR PREPARATION AND USE
US5679680A (en) * 1995-02-16 1997-10-21 Warner-Lambert Company α-substituted hydrazides having calpain inhibitory activity
US5958926A (en) * 1996-11-01 1999-09-28 Nitromed, Inc. Nitrosated and nitrosylated phosphodiesterase inhibitor compounds, compositions and their uses
USRE37234E1 (en) * 1996-11-01 2001-06-19 Nitromed, Inc. Nitrosated and nitrosylated phosphodiestrase inhibitor compounds, compositions and their uses
IL125950A0 (en) * 1997-09-05 1999-04-11 Pfizer Prod Inc Methods of administering ampa receptor antagonists to treat dyskinesias associated with dopamine agonist therapy
US20040152694A1 (en) * 2003-02-04 2004-08-05 Istvan Kurucz Methods and compositions for treating inflammatory disorders of the airways
KR101563103B1 (ko) * 2006-12-13 2015-10-23 아스카 세이야쿠 가부시키가이샤 퀴녹살린 유도체
EP2338492A1 (en) 2009-12-24 2011-06-29 Universidad del Pais Vasco Methods and compositions for the treatment of alzheimer
ES2747423T3 (es) 2010-09-07 2020-03-10 Astellas Pharma Inc Compuesto de quinoxalina

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4400382A (en) * 1980-05-09 1983-08-23 Usv Pharmaceutical Corporation Thiazoloquinoxalin-1,4-diones for treating allergy
US4354027A (en) * 1980-05-19 1982-10-12 Usv Pharmaceutical Corporation Triazoloquinoxalin-4-ones
US4623725A (en) * 1982-10-18 1986-11-18 Pfizer Inc. [1,2,4]Triazolo[4,3-a]quinoxaline-4-amine derivatives
US4780464A (en) * 1986-12-08 1988-10-25 Warner-Lambert Company (1,2,4)triazolo(4,3-a)quinoxaline-4-amines
DK160941C (da) * 1988-06-28 1991-10-21 Novo Nordisk As Kondenserede 2,3-dihydroxypyraziner, fremgangsmaade til deres fremstilling og farmaceutiske praeparater, hvori forbindelserne indgaar
US4975430A (en) * 1989-06-16 1990-12-04 The State Of Oregon Acting By And Through The State Board Of Education On Behalf Of The Oregon Health Sciences University CNQX and its analogs as therapeutics for degenerative neural diseases
DK0556393T3 (da) * 1990-11-06 2000-10-16 Yamanouchi Pharma Co Ltd Tilkondenseret pyrazinderivat
PT101004B (pt) * 1991-10-26 1999-10-29 Schering Ag Derivados da quinoxalina, processo para a sua preparacao e composicoes farmaceuticas que os contem
FR2690160A1 (fr) * 1992-04-15 1993-10-22 Rhone Poulenc Rorer Sa Application de dérivés d'acide 2H-1,2,4-benzothiadiazine-1,1-dioxyde-3-carboxylique à la préparation de médicaments, les produits nouveaux, leur préparation et les médicaments les contenant.

Also Published As

Publication number Publication date
IL103160A0 (en) 1993-02-21
NO940989D0 (no) 1994-03-18
JPH07501791A (ja) 1995-02-23
AU663523B2 (en) 1995-10-12
CA2119579A1 (en) 1993-04-01
US5504085A (en) 1996-04-02
DK162491D0 (da) 1991-09-20
FI941287A0 (fi) 1994-03-18
AU2660092A (en) 1993-04-27
NO302368B1 (no) 1998-02-23
WO1993006103A1 (en) 1993-04-01
FI941287A (fi) 1994-03-18
EP0633885A1 (en) 1995-01-18
TW210341B (no) 1993-08-01
NZ244398A (en) 1995-02-24
FI106719B (fi) 2001-03-30
NO940989L (no) 1994-03-18
ZA927172B (en) 1993-03-24

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Legal Events

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FF Patent granted
KB Patent renewed
RH1 Patent not in force