FI104822B - Menetelmä karbapeneemi- ja peneemiyhdisteiden valmistamiseksi - Google Patents

Menetelmä karbapeneemi- ja peneemiyhdisteiden valmistamiseksi Download PDF

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Publication number
FI104822B
FI104822B FI933926A FI933926A FI104822B FI 104822 B FI104822 B FI 104822B FI 933926 A FI933926 A FI 933926A FI 933926 A FI933926 A FI 933926A FI 104822 B FI104822 B FI 104822B
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FI
Finland
Prior art keywords
group
groups
formula
carbon atoms
pnb
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FI933926A
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English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI933926A0 (fi
FI933926A (fi
Inventor
Akira Yoshida
Kozo Oda
Original Assignee
Sankyo Co
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Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of FI933926A0 publication Critical patent/FI933926A0/fi
Publication of FI933926A publication Critical patent/FI933926A/fi
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Publication of FI104822B publication Critical patent/FI104822B/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/02Preparation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20Sulfur atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Production Of Liquid Hydrocarbon Mixture For Refining Petroleum (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Eye Examination Apparatus (AREA)
FI933926A 1992-09-09 1993-09-08 Menetelmä karbapeneemi- ja peneemiyhdisteiden valmistamiseksi FI104822B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP24082592 1992-09-09
JP24082592 1992-09-09
JP32511492 1992-12-04
JP32511492 1992-12-04

Publications (3)

Publication Number Publication Date
FI933926A0 FI933926A0 (fi) 1993-09-08
FI933926A FI933926A (fi) 1994-03-10
FI104822B true FI104822B (fi) 2000-04-14

Family

ID=26534948

Family Applications (1)

Application Number Title Priority Date Filing Date
FI933926A FI104822B (fi) 1992-09-09 1993-09-08 Menetelmä karbapeneemi- ja peneemiyhdisteiden valmistamiseksi

Country Status (21)

Country Link
EP (1) EP0587436B1 (da)
KR (1) KR100300365B1 (da)
CN (1) CN1048494C (da)
AT (1) ATE192747T1 (da)
AU (1) AU661793B2 (da)
CA (1) CA2105746A1 (da)
CZ (1) CZ287608B6 (da)
DE (1) DE69328600T2 (da)
DK (1) DK0587436T3 (da)
ES (1) ES2147743T3 (da)
FI (1) FI104822B (da)
GR (1) GR3033555T3 (da)
HK (1) HK1011975A1 (da)
HU (1) HUT65301A (da)
IL (1) IL106959A (da)
MX (1) MX9305548A (da)
NO (1) NO304981B1 (da)
NZ (1) NZ248629A (da)
PT (1) PT587436E (da)
RU (1) RU2070555C1 (da)
TW (1) TW368503B (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5496816A (en) * 1994-03-14 1996-03-05 Merck & Co., Inc. Carbapenem antibacterial compounds, compositions containing such compounds and methods of treatment
IN191798B (da) 2000-11-03 2004-01-03 Ranbaxy Lab Ltd

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2862198D1 (en) * 1977-08-06 1983-04-14 Beecham Group Plc Synthetic beta-lactam compounds, a process for their preparation and compositions containing them
EP0046363B1 (en) * 1980-08-16 1984-11-14 Beecham Group Plc Process for the preparation of 2-thio penem derivatives and intermediates therefor
EP0060612A1 (en) * 1981-02-04 1982-09-22 Beecham Group Plc Process for the preparation of azabicyclo(3.2.0)-hept-2-ene derivatives
EP0061231A1 (en) * 1981-02-04 1982-09-29 Beecham Group Plc Process for the preparation of azabicyclo(3.2.0)-hept-2-ene derivatives
US4640915A (en) * 1982-03-29 1987-02-03 Fujisawa Pharmaceutical Co., Ltd. 1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives
JPS5946288A (ja) * 1982-09-10 1984-03-15 Sanraku Inc β−ラクタム誘導体の製造方法
EP0120613A1 (en) * 1983-03-02 1984-10-03 Beecham Group Plc Penem derivatives and precursors
US4614738A (en) * 1983-03-25 1986-09-30 Schering Corporation 2-(N-heterocycloaliphaticthio)penems
US4614737A (en) * 1983-10-14 1986-09-30 Pfizer Inc. 2-dioxacycloalkylthiopenem derivatives
US4820817A (en) * 1984-09-10 1989-04-11 Merck & Co., Inc. Process for preparing 3-substituted-6-substituted-7-oxo-1-azabicycl(3.2.0)-hept-2-ene-2-carboxylic acid

Also Published As

Publication number Publication date
HK1011975A1 (en) 1999-07-23
FI933926A0 (fi) 1993-09-08
MX9305548A (es) 1994-04-29
HU9302547D0 (en) 1993-11-29
KR940007031A (ko) 1994-04-26
NO933195D0 (no) 1993-09-08
AU661793B2 (en) 1995-08-03
CZ287608B6 (en) 2001-01-17
ATE192747T1 (de) 2000-05-15
RU2070555C1 (ru) 1996-12-20
NZ248629A (en) 1995-04-27
IL106959A (en) 2000-06-01
CA2105746A1 (en) 1994-03-10
FI933926A (fi) 1994-03-10
DK0587436T3 (da) 2000-08-07
EP0587436B1 (en) 2000-05-10
ES2147743T3 (es) 2000-10-01
DE69328600T2 (de) 2001-02-08
CZ187493A3 (en) 1994-04-13
NO304981B1 (no) 1999-03-15
DE69328600D1 (de) 2000-06-15
HUT65301A (en) 1994-05-02
CN1048494C (zh) 2000-01-19
GR3033555T3 (en) 2000-09-29
AU4624393A (en) 1994-03-17
PT587436E (pt) 2000-10-31
KR100300365B1 (ko) 2001-11-22
CN1094728A (zh) 1994-11-09
IL106959A0 (en) 1993-12-28
NO933195L (no) 1994-03-10
TW368503B (en) 1999-09-01
EP0587436A1 (en) 1994-03-16

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