DE69328600D1 - Verfahren zur Herstellung von Carbapenem- und Penemverbindungen und beteiligte Verbindungen in diesem Verfahren - Google Patents
Verfahren zur Herstellung von Carbapenem- und Penemverbindungen und beteiligte Verbindungen in diesem VerfahrenInfo
- Publication number
- DE69328600D1 DE69328600D1 DE69328600T DE69328600T DE69328600D1 DE 69328600 D1 DE69328600 D1 DE 69328600D1 DE 69328600 T DE69328600 T DE 69328600T DE 69328600 T DE69328600 T DE 69328600T DE 69328600 D1 DE69328600 D1 DE 69328600D1
- Authority
- DE
- Germany
- Prior art keywords
- compounds
- carbapenem
- penem
- preparation
- involved
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/02—Preparation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
- C07D477/20—Sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Production Of Liquid Hydrocarbon Mixture For Refining Petroleum (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Eye Examination Apparatus (AREA)
- Apparatus For Radiation Diagnosis (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP24082592 | 1992-09-09 | ||
| JP32511492 | 1992-12-04 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69328600D1 true DE69328600D1 (de) | 2000-06-15 |
| DE69328600T2 DE69328600T2 (de) | 2001-02-08 |
Family
ID=26534948
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69328600T Expired - Fee Related DE69328600T2 (de) | 1992-09-09 | 1993-09-09 | Verfahren zur Herstellung von Carbapenem- und Penemverbindungen und beteiligte Verbindungen in diesem Verfahren |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP0587436B1 (de) |
| KR (1) | KR100300365B1 (de) |
| CN (1) | CN1048494C (de) |
| AT (1) | ATE192747T1 (de) |
| AU (1) | AU661793B2 (de) |
| CA (1) | CA2105746A1 (de) |
| CZ (1) | CZ287608B6 (de) |
| DE (1) | DE69328600T2 (de) |
| DK (1) | DK0587436T3 (de) |
| ES (1) | ES2147743T3 (de) |
| FI (1) | FI104822B (de) |
| GR (1) | GR3033555T3 (de) |
| HK (1) | HK1011975A1 (de) |
| HU (1) | HUT65301A (de) |
| IL (1) | IL106959A (de) |
| MX (1) | MX9305548A (de) |
| NO (1) | NO304981B1 (de) |
| NZ (1) | NZ248629A (de) |
| PT (1) | PT587436E (de) |
| RU (1) | RU2070555C1 (de) |
| TW (1) | TW368503B (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5496816A (en) * | 1994-03-14 | 1996-03-05 | Merck & Co., Inc. | Carbapenem antibacterial compounds, compositions containing such compounds and methods of treatment |
| IN191798B (de) | 2000-11-03 | 2004-01-03 | Ranbaxy Lab Ltd |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2862198D1 (en) * | 1977-08-06 | 1983-04-14 | Beecham Group Plc | Synthetic beta-lactam compounds, a process for their preparation and compositions containing them |
| EP0046363B1 (de) * | 1980-08-16 | 1984-11-14 | Beecham Group Plc | Verfahren zur Herstellung von 2-Thio-penemderivaten und die Zwischenprodukte |
| EP0060612A1 (de) * | 1981-02-04 | 1982-09-22 | Beecham Group Plc | Verfahren zur Herstellung von Azabicyclo(3.2.0)-hept-2-en-Derivaten |
| EP0061231A1 (de) * | 1981-02-04 | 1982-09-29 | Beecham Group Plc | Verfahren zur Herstellung von Azabicyclo(3.2.0)-hept-2-en-Derivaten |
| US4640915A (en) * | 1982-03-29 | 1987-02-03 | Fujisawa Pharmaceutical Co., Ltd. | 1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives |
| JPS5946288A (ja) * | 1982-09-10 | 1984-03-15 | Sanraku Inc | β−ラクタム誘導体の製造方法 |
| EP0120613A1 (de) * | 1983-03-02 | 1984-10-03 | Beecham Group Plc | Penem-Derivate und Vorstufenverbindungen |
| US4614738A (en) * | 1983-03-25 | 1986-09-30 | Schering Corporation | 2-(N-heterocycloaliphaticthio)penems |
| US4614737A (en) * | 1983-10-14 | 1986-09-30 | Pfizer Inc. | 2-dioxacycloalkylthiopenem derivatives |
| US4820817A (en) * | 1984-09-10 | 1989-04-11 | Merck & Co., Inc. | Process for preparing 3-substituted-6-substituted-7-oxo-1-azabicycl(3.2.0)-hept-2-ene-2-carboxylic acid |
-
1993
- 1993-09-08 RU RU9393050367A patent/RU2070555C1/ru not_active IP Right Cessation
- 1993-09-08 FI FI933926A patent/FI104822B/fi active
- 1993-09-08 CA CA002105746A patent/CA2105746A1/en not_active Abandoned
- 1993-09-08 HU HU9302547A patent/HUT65301A/hu unknown
- 1993-09-08 NO NO933195A patent/NO304981B1/no unknown
- 1993-09-09 KR KR1019930018124A patent/KR100300365B1/ko not_active IP Right Cessation
- 1993-09-09 AU AU46243/93A patent/AU661793B2/en not_active Ceased
- 1993-09-09 CZ CZ19931874A patent/CZ287608B6/cs not_active IP Right Cessation
- 1993-09-09 MX MX9305548A patent/MX9305548A/es not_active IP Right Cessation
- 1993-09-09 NZ NZ248629A patent/NZ248629A/en unknown
- 1993-09-09 TW TW082107390A patent/TW368503B/zh active
- 1993-09-09 DK DK93307130T patent/DK0587436T3/da active
- 1993-09-09 PT PT93307130T patent/PT587436E/pt unknown
- 1993-09-09 AT AT93307130T patent/ATE192747T1/de not_active IP Right Cessation
- 1993-09-09 CN CN93119285A patent/CN1048494C/zh not_active Expired - Fee Related
- 1993-09-09 DE DE69328600T patent/DE69328600T2/de not_active Expired - Fee Related
- 1993-09-09 ES ES93307130T patent/ES2147743T3/es not_active Expired - Lifetime
- 1993-09-09 EP EP93307130A patent/EP0587436B1/de not_active Expired - Lifetime
- 1993-09-09 IL IL10695993A patent/IL106959A/xx not_active IP Right Cessation
-
1998
- 1998-12-10 HK HK98113078A patent/HK1011975A1/xx not_active IP Right Cessation
-
2000
- 2000-05-31 GR GR20000401247T patent/GR3033555T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| GR3033555T3 (en) | 2000-09-29 |
| IL106959A (en) | 2000-06-01 |
| NO933195D0 (no) | 1993-09-08 |
| DE69328600T2 (de) | 2001-02-08 |
| CA2105746A1 (en) | 1994-03-10 |
| RU2070555C1 (ru) | 1996-12-20 |
| IL106959A0 (en) | 1993-12-28 |
| HUT65301A (en) | 1994-05-02 |
| AU4624393A (en) | 1994-03-17 |
| PT587436E (pt) | 2000-10-31 |
| KR940007031A (ko) | 1994-04-26 |
| HK1011975A1 (en) | 1999-07-23 |
| FI104822B (fi) | 2000-04-14 |
| NO304981B1 (no) | 1999-03-15 |
| NO933195L (no) | 1994-03-10 |
| KR100300365B1 (ko) | 2001-11-22 |
| ATE192747T1 (de) | 2000-05-15 |
| ES2147743T3 (es) | 2000-10-01 |
| NZ248629A (en) | 1995-04-27 |
| CZ187493A3 (en) | 1994-04-13 |
| FI933926A0 (fi) | 1993-09-08 |
| CN1094728A (zh) | 1994-11-09 |
| EP0587436B1 (de) | 2000-05-10 |
| TW368503B (en) | 1999-09-01 |
| MX9305548A (es) | 1994-04-29 |
| FI933926A (fi) | 1994-03-10 |
| HU9302547D0 (en) | 1993-11-29 |
| AU661793B2 (en) | 1995-08-03 |
| EP0587436A1 (de) | 1994-03-16 |
| CZ287608B6 (en) | 2001-01-17 |
| CN1048494C (zh) | 2000-01-19 |
| DK0587436T3 (da) | 2000-08-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |