FI102612B1 - Menetelmä terapeuttisesti käyttökelpoisten trisyklo[18.6.1.0 ]heptakoseenien ja niiden johdannaisten valmistamiseksi - Google Patents

Menetelmä terapeuttisesti käyttökelpoisten trisyklo[18.6.1.0 ]heptakoseenien ja niiden johdannaisten valmistamiseksi

Info

Publication number
FI102612B1
FI102612B1 FI932035A FI932035A FI102612B1 FI 102612 B1 FI102612 B1 FI 102612B1 FI 932035 A FI932035 A FI 932035A FI 932035 A FI932035 A FI 932035A FI 102612 B1 FI102612 B1 FI 102612B1
Authority
FI
Finland
Prior art keywords
heptacocenes
tricyclo
derivatives
preparation
therapeutically useful
Prior art date
Application number
FI932035A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI102612B (fi
FI932035A (fi
FI932035A0 (fi
Inventor
Karl Baumann
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB929209815A external-priority patent/GB9209815D0/en
Priority claimed from GB939304927A external-priority patent/GB9304927D0/en
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of FI932035A0 publication Critical patent/FI932035A0/fi
Publication of FI932035A publication Critical patent/FI932035A/fi
Priority to FI982476A priority Critical patent/FI982476A0/fi
Application granted granted Critical
Publication of FI102612B1 publication Critical patent/FI102612B1/fi
Publication of FI102612B publication Critical patent/FI102612B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/18—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Transplantation (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Saccharide Compounds (AREA)
FI932035A 1992-05-07 1993-05-05 Menetelmä terapeuttisesti käyttökelpoisten trisyklo£18.6.1.0 |heptako seenien ja niiden johdannaisten valmistamiseksi FI102612B (fi)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI982476A FI982476A0 (fi) 1992-05-07 1998-11-16 Heteroatomeja sisältäviä trisyklisiä yhdisteitä

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929209815A GB9209815D0 (en) 1992-05-07 1992-05-07 Organic compounds,processes for their production and their use
GB939304927A GB9304927D0 (en) 1993-03-10 1993-03-10 Organic compounds

Publications (4)

Publication Number Publication Date
FI932035A0 FI932035A0 (fi) 1993-05-05
FI932035A FI932035A (fi) 1993-11-08
FI102612B1 true FI102612B1 (fi) 1999-01-15
FI102612B FI102612B (fi) 1999-01-15

Family

ID=26300836

Family Applications (2)

Application Number Title Priority Date Filing Date
FI932035A FI102612B (fi) 1992-05-07 1993-05-05 Menetelmä terapeuttisesti käyttökelpoisten trisyklo£18.6.1.0 |heptako seenien ja niiden johdannaisten valmistamiseksi
FI982476A FI982476A0 (fi) 1992-05-07 1998-11-16 Heteroatomeja sisältäviä trisyklisiä yhdisteitä

Family Applications After (1)

Application Number Title Priority Date Filing Date
FI982476A FI982476A0 (fi) 1992-05-07 1998-11-16 Heteroatomeja sisältäviä trisyklisiä yhdisteitä

Country Status (25)

Country Link
US (1) US5514685A (de)
EP (1) EP0569337B1 (de)
JP (1) JP2788392B2 (de)
KR (1) KR100292311B1 (de)
CN (1) CN1037773C (de)
AT (1) ATE155787T1 (de)
AU (1) AU668152B2 (de)
CA (1) CA2095659C (de)
CY (1) CY2126B1 (de)
CZ (1) CZ291773B6 (de)
DE (1) DE69312386T2 (de)
DK (1) DK0569337T3 (de)
ES (1) ES2105193T3 (de)
FI (2) FI102612B (de)
GR (1) GR3024754T3 (de)
HU (2) HUT66531A (de)
IL (1) IL105607A (de)
MY (1) MY109602A (de)
NO (1) NO305865B1 (de)
NZ (1) NZ247553A (de)
PH (1) PH30456A (de)
RU (1) RU2126009C1 (de)
SG (1) SG47011A1 (de)
SK (1) SK282061B6 (de)
TW (1) TW330936B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY110603A (en) * 1993-05-27 1998-08-29 Novartis Ag Tetrahydropyran derivatives
JP4155593B2 (ja) 1994-10-26 2008-09-24 ノバルティス・アクチエンゲゼルシャフト 医薬組成物
MY129435A (en) 1994-10-26 2007-04-30 Novartis Ag Pharmaceutical microemulsion preconcentrates
PT2198858E (pt) 1998-03-26 2011-09-01 Astellas Pharma Inc Composição farmacêutica de libertação constante que contém um macrólido como o tacrolimus
GB9826656D0 (en) 1998-12-03 1999-01-27 Novartis Ag Organic compounds
US7063857B1 (en) 1999-04-30 2006-06-20 Sucampo Ag Use of macrolide compounds for the treatment of dry eye
GB0008785D0 (en) 2000-04-10 2000-05-31 Novartis Ag Organic compounds
CA2492989C (en) 2002-07-23 2012-11-20 Novartis Ag Ophthalmic ointment composition comprising a drug, an ointment base and a solubilizing/dispersing agent
KR100469917B1 (ko) * 2002-09-09 2005-02-02 (주)조은식품 구수한 호박씨가 첨가된 호박엿 및 그 제조방법
KR100745493B1 (ko) * 2005-12-16 2007-08-03 주식회사농심 조직감이 향상된 사출 스낵 및 그 제조 방법
US8716293B2 (en) * 2010-04-02 2014-05-06 Janssen R&D Ireland Macrocyclic integrase inhibitors
ES2898849T3 (es) 2014-10-28 2022-03-09 Koushi Yamaguchi Medicamento para mejorar el síndrome de hipertensión inducida por el embarazo
JP7465806B2 (ja) 2018-08-10 2024-04-11 晃史 山口 母体と胎児との関係における液性免疫関連疾患の治療薬
WO2020129348A1 (ja) 2018-12-18 2020-06-25 晃史 山口 不妊・不育症または妊娠状態を改善するための薬剤

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4894366A (en) * 1984-12-03 1990-01-16 Fujisawa Pharmaceutical Company, Ltd. Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
US5254562A (en) * 1984-12-03 1993-10-19 Fujisawa Pharmaceutical Company, Ltd. Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
CA1316916C (en) * 1988-10-12 1993-04-27 David Askin Hydroxide mediated fk-506 rearrangement product
EP0364031B1 (de) * 1988-10-12 1992-12-23 Merck & Co. Inc. Verfahren zur Umlagerung von FK-506 unter Beteiligung von Hydroxid
KR920700212A (ko) * 1989-06-14 1992-02-19 쟝 크라머·한스 루돌프 하우스 헤테로원자-함유 트리사이클릭 화합물
EP0413532A3 (en) * 1989-08-18 1991-05-15 Fisons Plc Macrocyclic compounds
IE904050A1 (en) * 1989-11-13 1991-05-22 Merck & Co Inc Aminomacrolides and derivatives having immunosuppressive¹activity
US5260301A (en) * 1990-03-01 1993-11-09 Fujisawa Pharmaceutical Co., Ltd. Pharmaceutical solution containing FK-506
GB2246350A (en) * 1990-07-23 1992-01-29 Fujisawa Pharmaceutical Co Tricyclo compounds
EP0480623A1 (de) * 1990-10-11 1992-04-15 Merck & Co. Inc. Halomakrolide und Derivate mit immunosuppressiver Wirkung
WO1992013862A1 (en) * 1991-02-05 1992-08-20 Fujisawa Pharmaceutical Co., Ltd. Lactone compounds
JPH06510304A (ja) * 1991-09-05 1994-11-17 アボツト・ラボラトリーズ 大環状イムノモジュレーター

Also Published As

Publication number Publication date
MY109602A (en) 1997-03-31
EP0569337B1 (de) 1997-07-23
CZ291773B6 (cs) 2003-05-14
HUT66531A (en) 1994-12-28
SK282061B6 (sk) 2001-10-08
JPH0641144A (ja) 1994-02-15
KR940005631A (ko) 1994-03-22
DE69312386T2 (de) 1998-01-29
CA2095659C (en) 2005-08-09
CY2126B1 (en) 2002-06-21
KR100292311B1 (ko) 2001-09-17
CN1083486A (zh) 1994-03-09
CZ82993A3 (en) 1994-01-19
PH30456A (en) 1997-05-28
FI102612B (fi) 1999-01-15
FI932035A (fi) 1993-11-08
EP0569337A1 (de) 1993-11-10
AU3839393A (en) 1993-11-11
NO305865B1 (no) 1999-08-09
NZ247553A (en) 1995-07-26
IL105607A0 (en) 1993-09-22
DE69312386D1 (de) 1997-08-28
JP2788392B2 (ja) 1998-08-20
NO931627D0 (no) 1993-05-05
GR3024754T3 (en) 1997-12-31
SG47011A1 (en) 1998-03-20
CA2095659A1 (en) 1993-11-08
NO931627L (no) 1993-11-08
HU211135A9 (en) 1995-10-30
HU9301190D0 (en) 1993-07-28
FI982476A0 (fi) 1998-11-16
US5514685A (en) 1996-05-07
IL105607A (en) 1998-01-04
FI932035A0 (fi) 1993-05-05
RU2126009C1 (ru) 1999-02-10
AU668152B2 (en) 1996-04-26
ATE155787T1 (de) 1997-08-15
TW330936B (en) 1998-05-01
DK0569337T3 (da) 1998-01-19
SK43593A3 (en) 1995-07-11
CN1037773C (zh) 1998-03-18
ES2105193T3 (es) 1997-10-16

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Legal Events

Date Code Title Description
FG Patent granted

Owner name: NOVARTIS AG

GB Transfer or assigment of application

Owner name: NOVARTIS AG

MM Patent lapsed