FI102462B1 - Menetelmä nimesulidin syklodekstriinikompleksin valmistamiseksi - Google Patents
Menetelmä nimesulidin syklodekstriinikompleksin valmistamiseksiInfo
- Publication number
- FI102462B1 FI102462B1 FI925224A FI925224A FI102462B1 FI 102462 B1 FI102462 B1 FI 102462B1 FI 925224 A FI925224 A FI 925224A FI 925224 A FI925224 A FI 925224A FI 102462 B1 FI102462 B1 FI 102462B1
- Authority
- FI
- Finland
- Prior art keywords
- nimesulide
- preparation
- cyclodextrin complex
- cyclodextrin
- cyclodextrins
- Prior art date
Links
- HYWYRSMBCFDLJT-UHFFFAOYSA-N nimesulide Chemical compound CS(=O)(=O)NC1=CC=C([N+]([O-])=O)C=C1OC1=CC=CC=C1 HYWYRSMBCFDLJT-UHFFFAOYSA-N 0.000 title abstract 4
- 229960000965 nimesulide Drugs 0.000 title abstract 4
- 229920000858 Cyclodextrin Polymers 0.000 title abstract 3
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940097362 cyclodextrins Drugs 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Nanotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Medical Informatics (AREA)
- Pain & Pain Management (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Crystallography & Structural Chemistry (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Slide Fasteners, Snap Fasteners, And Hook Fasteners (AREA)
- Manufacture And Refinement Of Metals (AREA)
- Ceramic Products (AREA)
- Fats And Perfumes (AREA)
- Ink Jet (AREA)
- Ink Jet Recording Methods And Recording Media Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2039390 | 1990-05-22 | ||
| IT02039390A IT1248475B (it) | 1990-05-22 | 1990-05-22 | Composti di inclusione di nimesulide con ciclodestrine |
| IT9100043 | 1991-05-20 | ||
| PCT/IT1991/000043 WO1991017774A1 (en) | 1990-05-22 | 1991-05-20 | Inclusion compounds of nimesulide with cyclodextrins |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| FI925224L FI925224L (fi) | 1992-11-18 |
| FI925224A0 FI925224A0 (fi) | 1992-11-18 |
| FI102462B FI102462B (fi) | 1998-12-15 |
| FI102462B1 true FI102462B1 (fi) | 1998-12-15 |
Family
ID=11166307
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI925224A FI102462B1 (fi) | 1990-05-22 | 1992-11-18 | Menetelmä nimesulidin syklodekstriinikompleksin valmistamiseksi |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0534995B1 (enExample) |
| JP (1) | JP3417942B2 (enExample) |
| KR (1) | KR100198046B1 (enExample) |
| AT (1) | ATE116135T1 (enExample) |
| AU (1) | AU655183B2 (enExample) |
| DE (1) | DE69106361T2 (enExample) |
| DK (1) | DK0534995T3 (enExample) |
| ES (1) | ES2065687T3 (enExample) |
| FI (1) | FI102462B1 (enExample) |
| GR (1) | GR3015468T3 (enExample) |
| HK (1) | HK1006413A1 (enExample) |
| HU (1) | HU214336B (enExample) |
| IT (1) | IT1248475B (enExample) |
| NO (1) | NO304730B1 (enExample) |
| WO (1) | WO1991017774A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1255462B (it) * | 1992-07-28 | 1995-11-02 | Grazia Maffione | Metodo di preparazione di composti di inclusione di nimesulide con ciclodestrine |
| HU210922B (en) * | 1993-05-24 | 1995-09-28 | Europharmaceuticals Sa | Nimesulide alkali salt cyclodextrin inclusion complexes their preparation and pharmaceutical compositions containing them |
| BE1008307A3 (fr) * | 1994-06-16 | 1996-04-02 | Europharmaceuticals Sa | Sel de nimesulide hydrosoluble, solution aqueuse le contenant, sa preparation et son utilisation. |
| WO1997012608A1 (fr) | 1995-10-05 | 1997-04-10 | Helsinn Healthcare S.A. | Agent anti-inflammatoire externe |
| BR9509183A (pt) * | 1994-10-05 | 1997-12-30 | Helsinn Healthcare Sa | Agente antiinflamatório para uso externo |
| HUP9601442A3 (en) * | 1995-07-25 | 1999-03-29 | Panacea Biotec Ltd | Nes antinflammatory and analgetic pharmaceutical compositions, containing nimesulid for transdermal use, and process for producing them |
| HUP9601443A3 (en) * | 1996-05-29 | 1999-03-29 | Panacea Biotec Ltd | Injectable analgetic pharmaceutical compositions for intramuscular use containing nimesulid, and process for producing them |
| RU2157689C2 (ru) * | 1996-07-24 | 2000-10-20 | Панацея Биотек Лтд. | Фармацевтические композиции терапевтического антивоспалительного и болеутоляющего средства для местного нанесения и способ их получения |
| IN186315B (enExample) * | 1996-12-12 | 2001-08-04 | Panacea Biotec Ltd | |
| IT1291895B1 (it) | 1997-04-24 | 1999-01-21 | Errekappa Euroterapici S P A | Preparazione farmaceutica fluida a base di nimesulide per uso orale e rinofaringeo |
| WO1999041233A1 (en) * | 1998-02-17 | 1999-08-19 | Micio Pharma Chemical Aktiengesellschaft | A watersoluble nimesulide adduct also for injectable use |
| IT1298732B1 (it) * | 1998-03-13 | 2000-02-02 | Recordati Chem Pharm | Composizioni farmaceutiche orali assumibili senza liquidi,contenenti complessi di inclusione |
| KR100395247B1 (ko) * | 2000-08-30 | 2003-08-21 | 디디에스텍주식회사 | 비자극성 캡사이신 경피 투여 제형 |
| EP1902705A1 (en) * | 2006-09-22 | 2008-03-26 | Pharmatex Italia Srl | Injectable pharmaceutical nimesulide solutions |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR206496A1 (es) * | 1972-07-03 | 1976-07-30 | Riker Laboratories Inc | Procedimiento para la preparacion de 2-fenoxi-4-nitro-alquil o haloalquilsulfonanilidas |
-
1990
- 1990-05-22 IT IT02039390A patent/IT1248475B/it active IP Right Grant
-
1991
- 1991-05-20 ES ES91909437T patent/ES2065687T3/es not_active Expired - Lifetime
- 1991-05-20 HU HU9203649A patent/HU214336B/hu not_active IP Right Cessation
- 1991-05-20 KR KR1019920702903A patent/KR100198046B1/ko not_active Expired - Fee Related
- 1991-05-20 AU AU78665/91A patent/AU655183B2/en not_active Ceased
- 1991-05-20 WO PCT/IT1991/000043 patent/WO1991017774A1/en not_active Ceased
- 1991-05-20 DE DE69106361T patent/DE69106361T2/de not_active Expired - Fee Related
- 1991-05-20 HK HK98105690A patent/HK1006413A1/en not_active IP Right Cessation
- 1991-05-20 AT AT91909437T patent/ATE116135T1/de not_active IP Right Cessation
- 1991-05-20 EP EP91909437A patent/EP0534995B1/en not_active Expired - Lifetime
- 1991-05-20 JP JP50911991A patent/JP3417942B2/ja not_active Expired - Fee Related
- 1991-05-20 DK DK91909437.5T patent/DK0534995T3/da active
-
1992
- 1992-11-18 FI FI925224A patent/FI102462B1/fi not_active IP Right Cessation
- 1992-11-20 NO NO924492A patent/NO304730B1/no unknown
-
1995
- 1995-03-20 GR GR950400599T patent/GR3015468T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69106361T2 (de) | 1995-05-18 |
| ES2065687T3 (es) | 1995-02-16 |
| WO1991017774A1 (en) | 1991-11-28 |
| NO304730B1 (no) | 1999-02-08 |
| KR937000160A (ko) | 1993-03-13 |
| IT9020393A1 (it) | 1991-11-22 |
| HUT65418A (en) | 1994-06-28 |
| JP3417942B2 (ja) | 2003-06-16 |
| FI102462B (fi) | 1998-12-15 |
| DK0534995T3 (da) | 1995-05-01 |
| FI925224L (fi) | 1992-11-18 |
| AU7866591A (en) | 1991-12-10 |
| DE69106361D1 (de) | 1995-02-09 |
| EP0534995A1 (en) | 1993-04-07 |
| HU214336B (hu) | 1998-03-02 |
| NO924492L (no) | 1993-01-20 |
| KR100198046B1 (ko) | 1999-06-15 |
| ATE116135T1 (de) | 1995-01-15 |
| EP0534995B1 (en) | 1994-12-28 |
| FI925224A0 (fi) | 1992-11-18 |
| JPH06502842A (ja) | 1994-03-31 |
| AU655183B2 (en) | 1994-12-08 |
| GR3015468T3 (en) | 1995-06-30 |
| NO924492D0 (no) | 1992-11-20 |
| HK1006413A1 (en) | 1999-02-26 |
| IT9020393A0 (enExample) | 1990-05-22 |
| IT1248475B (it) | 1995-01-19 |
| HU9203649D0 (en) | 1993-03-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK0569505T3 (da) | 3-Difluormethylpyrazolcarboxamidfungicider | |
| FI935396L (fi) | Uudet nanopartikkelien muodossa olevat, veren röntgenvarjoainekoostumukset, joissa on suuren molekyylipainon pinta-aktiivista ainetta | |
| FI933656A0 (fi) | 2,4-diaminokinazolinderivat, som foerstaerker antitumoeraktivitet | |
| ATE144523T1 (de) | Glykosylierte arzneimittel-vorstufen, verfahren zu ihrer herstellung und ihre verwendungen | |
| ATE109002T1 (de) | Wasserlösliche antineoplastische taxolderivate. | |
| NO910711L (no) | Middel bestaaende av cavitat- eller clathrat- dannende vert/gjest-komplekser som kontrastmiddel. | |
| NO913885D0 (no) | Fibere for spontan transport av fluider. | |
| FI73995B (fi) | Foerfarande foer framstaellning av farmakologiskt vaerdefulla 6,11-dihydro-dibenso-/b,e/-tiepin-11-n-alkyl- norskopinetrar. | |
| FI913917A0 (fi) | 3-amidopyrazolderivat, foerfarande foer framstaellning av dessa och farmaceutiska kompositioner innehaollande dessa. | |
| FI925224A0 (fi) | Inklusionfoereningar av nimesulid med cyklodextriner | |
| PT98481A (pt) | Processo para a preparacao de clatratos de peroxiacidos | |
| DE68906011D1 (de) | Chitosan enthaltendes kosmetisches praeparat. | |
| ATE190659T1 (de) | Rekombinante immuntoxine | |
| ATE140467T1 (de) | Hilfsstoffzusammensetzungen in fester form, dispergieren in wässerigen medien | |
| NO913887L (no) | Inklusjonskomplekser med silybinin, fremstilling av disseog farmasoeytiske preparater inneholdende disse | |
| DE69321585D1 (de) | PArENTERALE LÖSUNGEN ENTHALTEND 3-DIALKYLAMINOETHOXYBENZOYLBENZOFURANE | |
| DE60012404D1 (de) | Zahnpaste | |
| EP0295476A3 (en) | Inclusion complexes of dipyridamole with cyclodextrins | |
| FR2670206B1 (fr) | Procede de preparation de derives de l'acide dihydroxy-3,5 pentanouique. | |
| FI903779A0 (fi) | S-substituerade betatioacrylamider och deras anvaendning som mikrobicider. | |
| GR3002215T3 (en) | Calcium lactate-glycerine additive, process for its preparation and its use | |
| DE3473826D1 (en) | N,n-diethyl-5-methyl-2h-1-benzothiopyrano-(4,3,2-cd)-indazole-2-ethanamine, compositions comprising the same and uses therefor | |
| DE69112642D1 (de) | Glutaminhaltige lyophilisierte aminokarbonsäurenzusammensetzungen. | |
| FI904932A0 (fi) | Optiskt aktiva tiazetokinolin-3 -karboxylsyraderivat, foerfarande foer deras framstaellning och dessa innehaollande farmaceutiska kompositioner. | |
| IT1265430B1 (it) | Derivati del pirrolo e loro impieghi |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GB | Transfer or assigment of application |
Owner name: PATPHARM HOLDING SA |
|
| GB | Transfer or assigment of application |
Owner name: PATPHARM HOLDING SA |
|
| MA | Patent expired |