ES8705233A1 - Un procedimiento para la deposicion en un vial de 7-(dimetilaminometileno)amino-9a-metoximitosano - Google Patents

Un procedimiento para la deposicion en un vial de 7-(dimetilaminometileno)amino-9a-metoximitosano

Info

Publication number
ES8705233A1
ES8705233A1 ES552323A ES552323A ES8705233A1 ES 8705233 A1 ES8705233 A1 ES 8705233A1 ES 552323 A ES552323 A ES 552323A ES 552323 A ES552323 A ES 552323A ES 8705233 A1 ES8705233 A1 ES 8705233A1
Authority
ES
Spain
Prior art keywords
vial
methoxymitosane
dimethylaminomethylene
deposition
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES552323A
Other languages
English (en)
Other versions
ES552323A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of ES8705233A1 publication Critical patent/ES8705233A1/es
Publication of ES552323A0 publication Critical patent/ES552323A0/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)

Abstract

METODO DE DEPOSICION DE VIALES DE 7-(DIMETILAMINOMETILEN)AMINO-9A-METOXIMITOSANO EN FORMA DE DOSIS UNIDAD ESTERIL. CONSISTE EN INTRODUCIR EN UN VIAL ESTERIL UNA DISOLUCION DE 7-(DIMETILAMINOMETILEN)AMINO-9A-METOXIMITOSANO EN BUTANOL TERCIARIO; SEGUIDO DE ELIMINACION DEL BUTANOL CITADO, POR CONGELACION A C40JC Y SUBLIMADO A ALTO VACIO O POR EVAPORACION A VACIO A UNA TEMPERATURA COMPRENDIDA ENTRE 25JC Y 30JC. ESTOS VIALES TIENEN APLICACIONES PARA EL TRATAMIENTO DEL ADENOCARCINOMA DISEMINADO DEL ESTOMAGO O DEL PANCREAS.
ES552323A 1985-02-25 1986-02-24 Un procedimiento para la deposicion en un vial de 7-(dimetilaminometileno)amino-9a-metoximitosano Expired ES8705233A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US70524385A 1985-02-25 1985-02-25

Publications (2)

Publication Number Publication Date
ES8705233A1 true ES8705233A1 (es) 1987-05-01
ES552323A0 ES552323A0 (es) 1987-05-01

Family

ID=24832630

Family Applications (1)

Application Number Title Priority Date Filing Date
ES552323A Expired ES8705233A1 (es) 1985-02-25 1986-02-24 Un procedimiento para la deposicion en un vial de 7-(dimetilaminometileno)amino-9a-metoximitosano

Country Status (29)

Country Link
US (1) US4792566A (es)
JP (1) JPS61246125A (es)
KR (1) KR860006267A (es)
CN (1) CN1011289B (es)
AT (1) AT392001B (es)
AU (1) AU593786B2 (es)
BE (1) BE904272A (es)
CA (1) CA1262097A (es)
CH (1) CH670387A5 (es)
DD (1) DD243207A5 (es)
DE (1) DE3605888A1 (es)
DK (1) DK166307C (es)
ES (1) ES8705233A1 (es)
FI (1) FI83038C (es)
FR (1) FR2581870B1 (es)
GB (1) GB2171408B (es)
GR (1) GR860534B (es)
HU (1) HU193850B (es)
IT (1) IT1188708B (es)
LU (1) LU86320A1 (es)
MY (1) MY102923A (es)
NL (1) NL8600455A (es)
NO (1) NO169323C (es)
NZ (1) NZ215122A (es)
OA (1) OA08211A (es)
PT (1) PT82078B (es)
SE (1) SE8600830L (es)
YU (1) YU45304B (es)
ZA (1) ZA86308B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5216011A (en) * 1989-09-01 1993-06-01 Bristol-Myers Squibb Co. Stable solutions of mitomycin c
CN101581054B (zh) * 2009-05-27 2012-02-15 安徽万邦高森造纸有限公司 一种涂胶碱性电池隔膜纸的纸浆料及应用该纸浆料制备隔膜纸的制备工艺
PL2865391T3 (pl) * 2013-10-22 2018-01-31 Medac Ges Fuer Klinische Spezialpraeparate Mbh Sposób wytwarzania liofilizowanej kompozycji farmaceutycznej zawierającej mitomycynę C

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3660578A (en) * 1957-04-06 1972-05-02 Kyowa Hakko Kogyo Kk Mitomycin c
ZA833967B (en) * 1982-06-04 1984-02-29 Bristol Myers Co Amidines
US4487769A (en) * 1982-06-04 1984-12-11 Bristol-Myers Company Amidines
JPS60255789A (ja) * 1984-06-01 1985-12-17 Kyowa Hakko Kogyo Co Ltd マイトマイシン誘導体，その製造法および抗腫瘍剤
US4639528A (en) * 1985-02-21 1987-01-27 Bristol-Myers Company Crystalline form of 7-(dimethylaminomethylene-amino-9a-methoxymitosane
DE3674043D1 (de) * 1985-04-10 1990-10-18 Kyowa Hakko Kogyo Kk Pharmakologisch aktive mitomycinderivate.

Also Published As

Publication number Publication date
IT1188708B (it) 1988-01-28
OA08211A (fr) 1987-10-30
LU86320A1 (fr) 1986-09-02
SE8600830L (sv) 1986-08-26
AT392001B (de) 1991-01-10
IT8619493A0 (it) 1986-02-21
YU45304B (en) 1992-05-28
NO169323C (no) 1992-06-10
DK166307C (da) 1993-08-23
NO169323B (no) 1992-03-02
ZA86308B (en) 1986-11-26
FI860735A (fi) 1986-08-26
NZ215122A (en) 1989-06-28
HUT40327A (en) 1986-12-28
GB2171408A (en) 1986-08-28
DD243207A5 (de) 1987-02-25
FI860735A0 (fi) 1986-02-19
FR2581870B1 (fr) 1989-03-03
DE3605888A1 (de) 1986-08-28
NO860668L (no) 1986-08-26
ATA49686A (de) 1990-07-15
FI83038C (fi) 1991-05-27
GB8604514D0 (en) 1986-04-03
MY102923A (en) 1993-03-31
GB2171408B (en) 1988-07-13
KR860006267A (ko) 1986-09-09
CN86100997A (zh) 1986-10-22
NL8600455A (nl) 1986-09-16
AU5368486A (en) 1986-08-28
FR2581870A1 (fr) 1986-11-21
AU593786B2 (en) 1990-02-22
SE8600830D0 (sv) 1986-02-24
US4792566A (en) 1988-12-20
PT82078A (en) 1986-03-01
FI83038B (fi) 1991-02-15
DK85486D0 (da) 1986-02-24
JPS61246125A (ja) 1986-11-01
CN1011289B (zh) 1991-01-23
BE904272A (fr) 1986-08-25
CH670387A5 (es) 1989-06-15
YU25986A (en) 1987-12-31
CA1262097A (en) 1989-10-03
GR860534B (en) 1986-06-24
DK85486A (da) 1986-08-26
PT82078B (pt) 1988-07-01
HU193850B (en) 1987-12-28
DK166307B (da) 1993-04-05
ES552323A0 (es) 1987-05-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970401